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Name : aphE (MYCMA_1289) Accession : YP_006521038.1 Strain : Mycobacterium abscessus GO 06 Genome accession: NC_018150 Putative virulence/resistance : Resistance Product : streptomycin 3''-kinase Function : - COG functional category : - COG ID : - EC number : 2.7.1.87 Position : 2442906 - 2443619 bp Length : 714 bp Strand : + Note : - DNA sequence : GTGTACCGCTCGCCCGACGGTTCTCGCTATGCGAAAGAAGGCGGTGCCGATCTTGCGGGTGAGCGGGACCGCATCGAATG GCTTAGTGCTCAACGTATCCCGGGCCCGTCGGTGCTCGAGTGGGCGACCACGCCGGACGGCCCGCTGCTGATCACCTCGG CGGTACCGGGCGTACCCGCCGACCAGCTCGACTCCGAGGGTTTGGGCAGGGCATGGTCTGCCATCGCCGCAGCGGTGCGG GACCTGCACGCGCTGCCGACAGCGGGCTGTCCGTTTTCGCGGGAACTGGCCGCCATGGCAACGTTGGCCCGCGACGTCGT GGCCCGCGACGCCGTGAACCCGGATTTTCTGACCGACGAAGACCGGGAGAGGCCGGCGACCGAGCTGCTATGCCGTGTTG TGGCCGAACTGCCTCGGCGCCTGGCTCAGGAGCCCGACGACCTGGTGGTGTGCCATGGGGACTTGTGCCTGCCGAATATC GTCATCGCGCCCGGAGACTTCTCGGTGGCAGGTTTCATCGATCTCGGCCGGCTCGGGTTGGCCGACCGGCACGCCGATCT GGCCCTGCTCTTCGCCAATGCCCGGGAGACCTGGCCCGGGGACGGCTGGGTCGCGGCCGCCGCCCACGAGCGGTTCCTGA ACCCGTACGGAGCGCCTGCCGACCCCGAACGGTTGGCGTTCTACCTGCGGTTGGATCCGCTGACCTGGGGATAG Protein sequence : MYRSPDGSRYAKEGGADLAGERDRIEWLSAQRIPGPSVLEWATTPDGPLLITSAVPGVPADQLDSEGLGRAWSAIAAAVR DLHALPTAGCPFSRELAAMATLARDVVARDAVNPDFLTDEDRERPATELLCRVVAELPRRLAQEPDDLVVCHGDLCLPNI VIAPGDFSVAGFIDLGRLGLADRHADLALLFANARETWPGDGWVAAAAHERFLNPYGAPADPERLAFYLRLDPLTWG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| strA | YP_005176180.1 | aminoglycoside 3''-phosphotransferase protein | Not tested | ICEPmu1 | Protein | 8e-50 | 49 |
| strA | AGK07089.1 | StrA streptomycin phosphotransferase | Not tested | SGI1 | Protein | 7e-50 | 49 |
| strA | AFV47972.1 | streptomycin (3') phosphotransferase StrA | Not tested | AbaR25 | Protein | 7e-50 | 49 |
| strA | AFV48000.1 | streptomycin (3') phosphotransferase StrA | Not tested | delta-AbaR25 | Protein | 7e-50 | 49 |
| strA | ACK44539.1 | StrA | Not tested | SGI1 | Protein | 7e-50 | 49 |
| strA | YP_001800932.1 | aminoglycoside-3''-phosphotransferase | Not tested | Not named | Protein | 1e-49 | 49 |
| strA | AEA34675.1 | aminoglycoside phosphotransferase | Not tested | Not named | Protein | 7e-50 | 49 |
| strA | AEQ20909.1 | StrA, APH(3')-Ib streptomycin(3') phosphotransferase | Not tested | Tn6166 | Protein | 1e-49 | 49 |
| strA | AFH57207.1 | streptomycin resistance protein | Not tested | AbaR4a | Protein | 7e-50 | 49 |
| strA | AEZ06049.1 | StrA, APH(3')-Ib, streptomycin(3') phosphotransferase | Not tested | Tn6167 | Protein | 1e-49 | 49 |
| strA | AGK07031.1 | StrA streptomycin phosphotransferase | Not tested | SGI1 | Protein | 7e-50 | 49 |
| strA | CAJ77025.1 | Streptomycin phosphotransferase A | Not tested | AbaR1 | Protein | 4e-50 | 49 |
| ABK1_0266 | YP_005512838.1 | StrA | Not tested | AbaR4d | Protein | 9e-50 | 49 |
| BJAB07104_00282 | YP_008207747.1 | Aminoglycoside phosphotransferase | Not tested | AbaR25 | Protein | 9e-50 | 49 |
| ABZJ_00266 | YP_005524222.1 | hypothetical protein | Not tested | AbaR22 | Protein | 9e-50 | 49 |
| ABK1_0258 | YP_005512830.1 | StrA | Not tested | AbaR4d | Protein | 1e-49 | 49 |
| BJAB0868_00286 | YP_008211612.1 | Aminoglycoside phosphotransferase | Not tested | AbaR26 | Protein | 4e-49 | 48 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| aphE | YP_006521038.1 | streptomycin 3''-kinase | DQ336355.1.orf1.gene | Protein | 1e-51 | 55 |
| aphE | YP_006521038.1 | streptomycin 3''-kinase | AF024602.1.gene5.p01 | Protein | 5e-50 | 49 |
| aphE | YP_006521038.1 | streptomycin 3''-kinase | K00432.1.orf2.gene.p | Protein | 6e-29 | 44 |
