Gene Information

Name : dhbE (MYCMA_1203)
Accession : YP_006520954.1
Strain : Mycobacterium abscessus GO 06
Genome accession: NC_018150
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2275185 - 2276837 bp
Length : 1653 bp
Strand : -
Note : -

DNA sequence : 
ATGACTCAGCCCAGATCGACCACCACCGCGTCGTCAACCGCAACCCCCGCACTGGATGGCTTCGTCCCGTTTCCCTCGGT
ACGCGCCGACGAATATCGCCGGGCCGGGTACTGGACGGGCCACACCGTCGAATCGCTGCTTCGCGTGTCCGCGGCCAGGC
GGCCAGGCCACCCGGCTGTGATCGACGAACACCGCGCGCTGAGCTATCGAGAACTGGACGAGGCAGCCGACAATGCCGCA
CACGCCTTCCTCCGGCTGGGGATAGCACCCGGCGATCGGGTGCTGCTCCAACTCCCCAATCGGGCATCGTTTGCCGTCGC
GCTATTCGGCTTGATGCGCGCCGGCGCAATACCCGTGATGTGCCTTCCCGGGCACCGGGCCGCCGAACTGTCCCACTTCA
TCGAGGTGGCCGACGCTGTCGGATTGGTTATCCCCGATTCGGCCGGAGGATTCGATTACCGCGCGCTGGCGGTCGCGCTG
TCCCAGCAGCATCCGCGCCTGCGCACGGTGGTTGTGGAGGGTGATGCGGGCCCCTTCACATCCTGGACGTCGCTGCTGAA
AAGCGTTGAACCGCAAGGTCCGCTACCTCCCGTACAGACGGACACTCCTGCCCTACTGCTGGTATCCGGCGGCACCACCG
CAGCACCCAAGCTGATCCCCCGCACCCACGAGGACTACGTCTACAACGCCACACAGGCAGCACGGGTCTGCGGTCTGACC
CAAGACGACGTTTACCTCGTGGCGCTGCCCGCCGGCCATAATTTCCCGCTGGCTTGCCCGGGCTTGCTTGGTGCGATAAG
CACGGGTGCGACCACGGTTTTCCTCTCGGATCCAAGTCCGGAGTCGGCTTTCGCGACCATCGCTCGCCATCGGGTGTCGG
TGACGGCAGTGGTGCCATCGCTTGCACAGCTGTGGGCTCAAGCCACCGCGTGGGAGCCGGTGCTGCCAGAAACACTGAGG
CTGCTCCAGGTCGGTGGCGCCAAACTCGGCGCCGACGACGCACGCGCGGTACGAGAGTCGCTCACCCAGGGACTGCAACA
GGTTTTCGGCATGGCAGAGGGCCTGTTATGCCTCACCCGGCCAGGCGATCCCACCGATATCCTGGATAACAGCCAGGGCC
GGCCGATGTGCGATGCGGACGAGGTGCGCATTGTCGACGAGGACGGTGCCGACGTCCCCGCCGGAGAAACCGGGGAACTG
CTCGTGCGTGGGCCGTACACCCTCAGCGGGTACTACCGCGCCGACGCCGACAACATGCGCTCGTTCACTGCCGACGGTTT
CTATCGCAGCGGTGACCGGGTACGCGCGCTACCGGGCGGTTATCTGGAAGTCACCGGACGCATCAAGGATGTCATTCTCC
GTGGCGGGGAATCCATCGCCGCGTTGGACCTCGAATCGCACTTGCAGACCCATCCGGCGGTCTACGCCGCAGCGGCGGTG
GGCCTTCCGGACCAGTATCTTGGCGAGATTGTCTGTGCTGCAATTGTTTTCAAAGGAAAGCCGGTCACCGCCGCCGAACT
CAACCAGCATCTGCAGGCCCGTGGCGCCGCGACCCATTCGCGCGTCGACAAACTGGTCGCCGTTTCCGCACTGCCCCTGA
CCGCTGTGGGCAAGATCGACAAGCGAGCGCTGCTGGCCTCCCTGACGAGCTAG

Protein sequence : 
MTQPRSTTTASSTATPALDGFVPFPSVRADEYRRAGYWTGHTVESLLRVSAARRPGHPAVIDEHRALSYRELDEAADNAA
HAFLRLGIAPGDRVLLQLPNRASFAVALFGLMRAGAIPVMCLPGHRAAELSHFIEVADAVGLVIPDSAGGFDYRALAVAL
SQQHPRLRTVVVEGDAGPFTSWTSLLKSVEPQGPLPPVQTDTPALLLVSGGTTAAPKLIPRTHEDYVYNATQAARVCGLT
QDDVYLVALPAGHNFPLACPGLLGAISTGATTVFLSDPSPESAFATIARHRVSVTAVVPSLAQLWAQATAWEPVLPETLR
LLQVGGAKLGADDARAVRESLTQGLQQVFGMAEGLLCLTRPGDPTDILDNSQGRPMCDADEVRIVDEDGADVPAGETGEL
LVRGPYTLSGYYRADADNMRSFTADGFYRSGDRVRALPGGYLEVTGRIKDVILRGGESIAALDLESHLQTHPAVYAAAAV
GLPDQYLGEIVCAAIVFKGKPVTAAELNQHLQARGAATHSRVDKLVAVSALPLTAVGKIDKRALLASLTS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-97 45
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-97 45
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 6e-99 45
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-99 45
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 8e-99 45
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-99 45
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-99 45
ybtE CAA21394.1 - Virulence HPI Protein 8e-99 45
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 8e-99 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_006520954.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-166 64
dhbE YP_006520954.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-91 42
dhbE YP_006520954.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 1e-85 41