Gene Information

Name : mbtI (MYCMA_1202)
Accession : YP_006520953.1
Strain : Mycobacterium abscessus GO 06
Genome accession: NC_018150
Putative virulence/resistance : Virulence
Product : Isochorismate synthase/isochorismate-pyruvate lyase mbtI
Function : -
COG functional category : -
COG ID : -
EC number : 5.4.4.2
Position : 2272782 - 2274143 bp
Length : 1362 bp
Strand : +
Note : -

DNA sequence :
GTGTCGAAGATGAGTGCGGTTGTAGATCCCGATACCGGCGCCCGGACCTGGGTTTCTGTGCAGGAGGGACTGCCGGATGG
CGTTGCCCCGGCCGATCTCGCCGGTGCGCTCGCGCAGGAAATCCCGGAGCGCCACGGCGACGAATACTTGATTTACGAGC
GCGACGGCGAATGGGTGCTCGCCATCGGCGCGCGCGCCTCCGTTGAACTCGACAGTGACGGACTGCGTATCGTCCGGGAC
GGAACCATCGAGAAACGCGATTGGTCCGGACACCCAGGCGCTGCCCTCGAACAGGCCGTGAACGAGATCTCCGACGGCAT
GCATCGAGTTTTCGGATGGGTCGCTTTTGAATTCGGCACCTACCGATTCAACCTTCAGCACCGGCTGGCTCCTGGTACGC
CGTTGGCTCGGGTCTTCGCTCCCCGTGCCGAGGTTGTGATCACCGCAGACGGGGTGTCGGTCTCTGATGAGAGCTATGTG
GAGGACATCAGCCGGCTGATCGAGCAGGGCGTACCGGCGATTCCGGCTCCGGCCTCGATCGATCTGGCCCCGGACCCATC
CGATTATCGGGGGCGTGTCGGCATCGCGACCGCCGAGATCCGGTCGGGCCTGTACCACAAGGTGATCCTGTCGCGTCGGG
TGGAAGTGCCTTTTGCCATGGACTTTCCGTCCACCTACCGTCTTGGGCGGCATAACAACACACCGGTTCGTTCCTTCCTG
TTGCGGCTCGGAGGTATTCGAGCTCTTGGCTACAGCCCAGAGCTCGTCACCGCGGTCGAGGCCGACGGAACTGTTGTCAC
CCAGCCGCTGGCGGGAACCCGTGCCTTCGGGCGCGGTGAGGACGCAGACCGTGTCGCCCGCGATGACCTCGAATCGAATG
CGAAAGAGATTGTCGAGCATGCGATCTCAGTACGAAGCTCGCTTGCCGAGATCGCCGAGGTGGTTGATCCCAGCAGTACC
AAGGTTACCGACTTCATGACCGTGCGTGAGCGTGGCAGTGTTCAGCACCTGGGATCGACAGTCAGTGGTGAGCTGAGTGC
CGGCATGACGCGGATGGATGCGCTGGAGGCGCTGTTTCCCGCCGTGACGGCTTCGGGCATCCCGAAGGCGGAAGGTGTCG
ACGCCATCCTTCGGCTCGATGATCACCCGCGTGGCCTTTACTCCGGTGCGGTTGTCATGCTGTCGCCGAACGGCGGCTTG
GACGCCGCGCTGACGCTGCGCTCGGCCTACGAACAGGACGGCCACACCTGGCTGCGGGCCGGTGCAGGCATCATCGAGGC
ATCCACCCCCGAGCGGGAGTTCGAGGAGACCTGCGAGAAGCTCGGCAGTATYGCCCCGTACGTGATCRAGCGCGAGGCAT
AG

Protein sequence :
MSKMSAVVDPDTGARTWVSVQEGLPDGVAPADLAGALAQEIPERHGDEYLIYERDGEWVLAIGARASVELDSDGLRIVRD
GTIEKRDWSGHPGAALEQAVNEISDGMHRVFGWVAFEFGTYRFNLQHRLAPGTPLARVFAPRAEVVITADGVSVSDESYV
EDISRLIEQGVPAIPAPASIDLAPDPSDYRGRVGIATAEIRSGLYHKVILSRRVEVPFAMDFPSTYRLGRHNNTPVRSFL
LRLGGIRALGYSPELVTAVEADGTVVTQPLAGTRAFGRGEDADRVARDDLESNAKEIVEHAISVRSSLAEIAEVVDPSST
KVTDFMTVRERGSVQHLGSTVSGELSAGMTRMDALEALFPAVTASGIPKAEGVDAILRLDDHPRGLYSGAVVMLSPNGGL
DAALTLRSAYEQDGHTWLRAGAGIIEASTPEREFEETCEKLGSIAPYVIXREA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAD17661.1 unknown Not tested HPI Protein 3e-60 41
ybtS YP_002346907.1 salicylate synthase Irp9 Not tested HPI Protein 3e-64 41
ybtS NP_669701.1 salicylate synthase Irp9 Not tested HPI Protein 3e-64 41
ybtS YP_070129.1 salicylate synthase Irp9 Not tested HPI Protein 3e-64 41
ybtS CAA21385.1 - Virulence HPI Protein 3e-64 41
APECO1_1052 YP_853070.1 salicylate synthase Irp9 Not tested PAI IV APEC-O1 Protein 3e-64 41