Gene Information

Name : clpC (HMPREF9154_0429)
Accession : YP_006510761.1
Strain : Propionibacterium propionicum F0230a
Genome accession: NC_018142
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 450146 - 452641 bp
Length : 2496 bp
Strand : +
Note : -

DNA sequence :
ATGTTCGAACGCTTCACTGATCGCGCCCGCCGTGTCATCGTGCTGGCGCAGGATGAGGCCAAGCTGTTAAACCACAACTA
CATCGGTACGGAACACCTGCTTCTCGGTCTGATTCACGAGGGCGAGGGCGTGGCCGCCAAGGCGCTGGAACAAATGGGAA
TCTCCCTGCAGGCGGCCCGTGAGCAGGTGGTCGAGATCATGGGCCAGGGGCAGCAGGTGCCGTCCGGGCACATCCCCTTC
TCGCCGCGCGCCAAGCGCGTGCTGGAACTCTCGCTGCGTGAGGCCCTGCAGATGAACCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGGCTGGTGCGGGAGGGCGAGGGAGTGGCCGCCCAGGTGCTCCTGAAGCTCGGGGCCGATCTCGGCCGGG
TGCGTTCCACCGTCATCCAGTTGCTGGCCGGGTATCAGGGCAAGGAGGCGTCCATGGCGGGCGCCCCTGAGGCCGGGCCG
GAGAAGTCCAGTTCGCAGGTGCTCGACCAGTTCGGCCGCAACCTCACCCAGGCGGCGCGCGAGAACCGGCTCGACCCGGT
GATCGGCCGTGTCAGCGAGATCGAGCGCGTCATGACGGTGCTCAGCCGCCGCACCAAGAACAACCCGGTGCTGATCGGCG
AACCGGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTCAGCCAGGCCATCGTCCGCGGCGACGTGCCCGAGACCCTGCGC
GACAAGCAGATCTACACCCTGGACCTGGGCGCTCTGGTCGCCGGTTCCCGCTACCGCGGCGATTTCGAGGAACGCCTGAA
GAAGGTGCTCAAGGAAATCAAGACCCGCGGCGACATCATGCTGTTCATCGACGAGATCCACACTCTCGTCGGTGCCGGTG
CCGCTGAGGGGGCCATCGACGCCGCCAGCATCCTCAAACCCATGCTGGCCCGCGGCGAGCTTCAGACCATCGGCGCCACC
ACCCTCGACGAGTACCGCAAACACATCGAGAAGGACGCCGCCCTGGAGCGCCGGTTCCAGCCGATCCAGGTGGCCGAGCC
GTCCGTCGCGCTGACCATCGACATCCTGAAGGGCCTGCGGGACCGCTACGAGGCCCACCACCGCATCACCATCACCGACG
AGGCCCTCACGGCCGCGGCGACGATGGCGGACCGCTACATCCAGGACCGGTTCCTGCCGGACAAGGCCATCGACCTGATC
GACGAGGCCGGTGCGCGGCTGCGCATCCAGCGGATGACCGCCCCGCCGGACCTGCGCGAGTTCGACGAGCAGATCGCGAA
ACTGAAGATGGAGAAGGACGCCGCCATCGACGCGCAGGACTTCGAGACCGCGGCCCGGCTGCGTGACGACGTCACCCGCA
TCCAGGCGCAGCGCGCGGAGAAGGAGGAGGCCTGGAAGCAGGGCGACTCCGACATTCCCGCAGTGGTGGGCGAGGAGGAG
ATCGCGGTCGTGCTGTCCAGCAGCACCGGTATCCCGGTGTTCAAGCTGACGGAGGAGGAGTCGGCGCGCCTGCTGCGCAT
GGAGCAGGAGCTGGGGAAGCGCTACATCGGGCAGGAGGACGCCGTCAAGGCCCTCGCCCGTTCGATCCGCCGCACCCGCG
CCGGCCTGAAGGACCCGAAGCGTCCCTCCGGTTCCTTCATCTTCGCCGGACCCTCGGGCGTCGGGAAGACGGAGCTCACC
AAGGCGCTCACCGAGTTCCTGTTCGGCGACGAGGACGCGCTCATCACCCTCGACATGAGCGAGTACTCCGAGAAGCACAC
CGCGTCCAGGATGTTCGGGTCCCCGCCCGGCTACGTCGGCTACGAGGAGGGCGGCCAGCTCACCGAGAAGGTGCGTCGCA
AGCCGTTCTCGGTGGTGCTGTTCGACGAGATCGAGAAGGCCCACCCCGACATCTTCAACTCGCTGCTGCAGATCCTCGAC
GAGGGGCGTCTCACCGACGCCCAGGGTCGCGTGGTGGACTTCAAGAACACCGTCATCGTGATGACCACCAACCTCGGGTC
CCGCGACATCAGCAAGGGAGTCAACCTCGGCTTCTCGCGGGCCGGGGATGAGGCCTCCAGCTACGAGAAGATGAAGGCGA
AGGTCTCCGACGAGCTGAAGCAGCACTTCCGTCCCGAGTTCCTGAACCGCGTCGACGAGATCGTCGTGTTCCACCAGCTC
ACGCAGTCCGACATCGAACGGATCGTGGACCTGATGGTGGCGCAGATCGAATCCCGCCTGGCGGACCGGGACATGGGCAT
CGAACTGACCCCGGCCGCGAAGACCCTCGTCGCCAAACGCGGCTTCGACCCGGTGCTCGGGGCGCGTCCCCTGCGCCGCG
CCCTGCAGCGCGACATCGAGGACGTGCTCGCCGAGAAGATCCTGTTCGGGGAGCTGGTCGCCGGGCAGATCGTCCAGGTG
GACGTCGCTGAGGAGGGTGCGGAACTGCCGTTCAAGTTCACGGGGATCTCCAAGACCCCGCCGGCTCTCCCCGCGGAGGC
CGGTCCCGTCGAATGA

Protein sequence :
MFERFTDRARRVIVLAQDEAKLLNHNYIGTEHLLLGLIHEGEGVAAKALEQMGISLQAAREQVVEIMGQGQQVPSGHIPF
SPRAKRVLELSLREALQMNHNYIGTEHILLGLVREGEGVAAQVLLKLGADLGRVRSTVIQLLAGYQGKEASMAGAPEAGP
EKSSSQVLDQFGRNLTQAARENRLDPVIGRVSEIERVMTVLSRRTKNNPVLIGEPGVGKTAVVEGLSQAIVRGDVPETLR
DKQIYTLDLGALVAGSRYRGDFEERLKKVLKEIKTRGDIMLFIDEIHTLVGAGAAEGAIDAASILKPMLARGELQTIGAT
TLDEYRKHIEKDAALERRFQPIQVAEPSVALTIDILKGLRDRYEAHHRITITDEALTAAATMADRYIQDRFLPDKAIDLI
DEAGARLRIQRMTAPPDLREFDEQIAKLKMEKDAAIDAQDFETAARLRDDVTRIQAQRAEKEEAWKQGDSDIPAVVGEEE
IAVVLSSSTGIPVFKLTEEESARLLRMEQELGKRYIGQEDAVKALARSIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELT
KALTEFLFGDEDALITLDMSEYSEKHTASRMFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHPDIFNSLLQILD
EGRLTDAQGRVVDFKNTVIVMTTNLGSRDISKGVNLGFSRAGDEASSYEKMKAKVSDELKQHFRPEFLNRVDEIVVFHQL
TQSDIERIVDLMVAQIESRLADRDMGIELTPAAKTLVAKRGFDPVLGARPLRRALQRDIEDVLAEKILFGELVAGQIVQV
DVAEEGAELPFKFTGISKTPPALPAEAGPVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 72

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_006510761.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 58
clpC YP_006510761.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 3e-154 51