Gene Information

Name : gacA/letA (LPV_2988)
Accession : YP_006509857.1
Strain : Legionella pneumophila HL06041035
Genome accession: NC_018140
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator in two-component regulatory system with BarA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3082473 - 3083132 bp
Length : 660 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12193630, 12533459, 20576358, 3295776, 3515318; Product type r : regulator

DNA sequence : 
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTGGTTGCAGATGCTGAAAGTGGGGAGCAGGCTTTAGCTTATGTGAAAACCCACTCCCCTGATGTCGTATTATTAG
ACATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGCTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCC
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAATCAGG
GGCTGAAGAAATGGCTGCTGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATTGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGCCTCAAGATTCCCCCTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACGAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGTTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAACACCCCAATG
ATTTGTCACAAGATGATTAG

Protein sequence : 
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQEPQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00306 YP_008211632.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR26 Protein 6e-55 56
BJAB07104_00302 YP_008207767.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR25 Protein 6e-55 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
gacA/letA YP_006509857.1 DNA-binding response regulator in two-component regulatory system with BarA VFG1889 Protein 1e-100 99