Gene Information

Name : mutS (LPV_2076)
Accession : YP_006509070.1
Strain : Legionella pneumophila HL06041035
Genome accession: NC_018140
Putative virulence/resistance : Virulence
Product : methyl-directed mismatch repair protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2119136 - 2121676 bp
Length : 2541 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12887908, 1938937, 88032849, 89112166, 92291095, 99410452; Product type e : enzyme

DNA sequence :
ATGGCTAGCTCTCACACACCAATGATGCAGCAATATTTGCGCATTAAAACAGACTATCCCGACATGCTTTTATTTTATCG
CATGGGTGATTTTTATGAGTTGTTTTTTGATGATGCCAAACGCGCGTCACAACTTTTGGATTTAACTCTGACACATAGAG
GACAATCTGCTGACAAACCTATTCCCATGGCCGGCGTTCCTTATCATGCGGTAGAAAACTATTTGGCACGATTATTAAAA
AAAGGGGAATCCGTAGCCATCTGTGAACAAATCGGAGATCCAGCTACCAGCAAAGGACCAGTAGAAAGACAAGTAACGCG
AATCATTACTCCTGGTACAGTAACAGATGAAGCATTATTAGATGCCAGAAAAGATAATATTTTGTTGGCCATACACACCC
AAAAACAAAAAATTGGTATTGCATGGGTTGATTTAGGTGGCGGTCGTTTTCATTTGCAGGAATTAACAGAAGAACATCAG
TTAAATGCAGAGTTAGTGCGCCTGCAACCAGCAGAACTCCTCTGCAAAGAATCCACGCCGCTTCCTTCATTTTGTTCTAA
CTTTGCTGTTAAATTCAGACCAGGATGGGAGTTTGATGCAAGCAACGCACATAAATTATTGTGTGAACAATTCTCCGTGA
CTGATCTTTCGGCCTTTGGCGAACAAAATTACCCCACTGCCTTGATTGCAGCAGGCGCTTTATTAGCTTATTTAAAAACC
ACTCAAAAACAGTCATTACCACATCTTACAACACTTACTCTTGAGCAATCCGAGGATTACCTGCAACTGGACGCATCGAC
TCAAAAGCACTTGGAGCTTTTTGAAAATATACATGGTGGTGGTGAGCACTGTTTGCTTTCCATATTAGATAAAACAGCTT
GTGCGATGGGAAGCCGTTTACTCAAACGTTGGCTGGGAAAACCATTAAAACAACATGCAATCATTCAAACAAGACAACAA
GCCATTAAGGAAATTATTTTTCTTCAACAAGACGTTTCACTTCATCAGCTGATTAAACAATGCGCCGATGTGGAGCGCAT
AGTATCACGTATTGCTTTAAAATCAGCGCGCCCACGTGATTTGGTTTCCTTATTGCAAACTCTGACACTGCTTCCAGCAA
TCCATGACGAATTACAAGAAAACAAGAGCTTGTTAATCAATGAAATCAAGAAAGAAATAAGCCCTCTCCCACTGCTGCAG
CAACTGCTTGAAACAGCCATTATAGACAACCCGCCAATGCTAATTAGGGATGGTGGAGTCATTGCTCCAGGATTTGATGA
AGAACTGGATGAGTTGCGTAATTTAAGTAGCAATGCTCATGAAACATTAGTAAAACTTGAACAGGAAGAAAAAAATCGCA
CAGGATTATCCACTCTAAAACTAGGTTACAATAGCGTTCAGGGATTTTATATTGAACTGTCAAAGGCACAAGCTCAAAAT
GCGCCGCCCCATTTTCACAGAAAGCAAACTTTAAAAAATGTGGAACGTTATATTACTCCCGAACTAAAGCTGTTCGAAGA
CAAGGTGCTTTCAGCTCAATCCAAAGCATTGGCTCGCGAAAAATGGCTATATGACAATTTGCTTGAAGAAATTCAGCAAT
ACATACCTGAGTTATCGGATCTTGCAAAATCTCTGGCGCAATTGGACGTATTGGTCACTCTTGCTGAAAGAGCACAAAGT
TTAAATTGGAATTGCCCGAATCTCGTTCCTGAATCAGGCATTATGATACAAGCCGGACGACATCCTGTCATTGAGCCATT
ATTACAAGAACGGTTTATCGCTAATGATTTGGAACTTAAACCAAATCAAAATATGTTACTAATCACTGGGCCCAACATGG
GCGGCAAATCGACCTACATGAGGCAAACCGCCTTAATCGTTCTGTTGGCACATATTGGAAGTTTTGTACCTGCTGATAAA
GTGACATTAGGTCCATTAGACCGAATCTTTACTCGCATTGGGGCCAGTGATGATTTATCCTCTGGACGTTCCACTTTTAT
GGTGGAAATGACTGAAACAGCTCAAATATTAAGGCAGGCAACCAGCCAAAGCCTCGTATTAATCGATGAAATTGGTCGTG
GTACCAGTACCTATGATGGAATGGCATTAGCTTATGCAAGCTGTGCCTTTCTTGCGTCAACAATAAAAGCCTATACTTTG
TTTTCTACTCATTACCTGGAGTTGACTGAATTACCCAAAGAATTCTCTTGTATTCGCAACGTGCATTTGCAAGCATCCAT
CAAGACAGGACAAATTGTTTTCTTGTACCGTGTCGAAGAAGGTTGCGCAAATCGTAGTTACGGATTAGAAGTCGCAGAAT
TAGCTGGCATACCTAAAGAAGTGCTAAAGCTGGCTCATGAACATCTGAATCAGATACAAGATACTCAATCTATCCTGGTC
CAGACTCAAATTATAAAGCCTCCCACATCTCCAGTTTTAACTGAACTAAAAAAAATTGATCCAGATAGATTAACTGCCAA
AGAAGCGTTGGATTTAATTTATAAGTTAAAACACCTGGAGTGTGCCGAGAGCATCAATTGA

Protein sequence :
MASSHTPMMQQYLRIKTDYPDMLLFYRMGDFYELFFDDAKRASQLLDLTLTHRGQSADKPIPMAGVPYHAVENYLARLLK
KGESVAICEQIGDPATSKGPVERQVTRIITPGTVTDEALLDARKDNILLAIHTQKQKIGIAWVDLGGGRFHLQELTEEHQ
LNAELVRLQPAELLCKESTPLPSFCSNFAVKFRPGWEFDASNAHKLLCEQFSVTDLSAFGEQNYPTALIAAGALLAYLKT
TQKQSLPHLTTLTLEQSEDYLQLDASTQKHLELFENIHGGGEHCLLSILDKTACAMGSRLLKRWLGKPLKQHAIIQTRQQ
AIKEIIFLQQDVSLHQLIKQCADVERIVSRIALKSARPRDLVSLLQTLTLLPAIHDELQENKSLLINEIKKEISPLPLLQ
QLLETAIIDNPPMLIRDGGVIAPGFDEELDELRNLSSNAHETLVKLEQEEKNRTGLSTLKLGYNSVQGFYIELSKAQAQN
APPHFHRKQTLKNVERYITPELKLFEDKVLSAQSKALAREKWLYDNLLEEIQQYIPELSDLAKSLAQLDVLVTLAERAQS
LNWNCPNLVPESGIMIQAGRHPVIEPLLQERFIANDLELKPNQNMLLITGPNMGGKSTYMRQTALIVLLAHIGSFVPADK
VTLGPLDRIFTRIGASDDLSSGRSTFMVEMTETAQILRQATSQSLVLIDEIGRGTSTYDGMALAYASCAFLASTIKAYTL
FSTHYLELTELPKEFSCIRNVHLQASIKTGQIVFLYRVEEGCANRSYGLEVAELAGIPKEVLKLAHEHLNQIQDTQSILV
QTQIIKPPTSPVLTELKKIDPDRLTAKEALDLIYKLKHLECAESIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 0.0 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mutS YP_006509070.1 methyl-directed mismatch repair protein VFG0562 Protein 0.0 54