Gene Information

Name : fliP (LPV_2059)
Accession : YP_006509053.1
Strain : Legionella pneumophila HL06041035
Genome accession: NC_018140
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2104196 - 2104945 bp
Length : 750 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1482109, 92407478, 94110225; Product type s : structure

DNA sequence :

ATGAAAATTAAAAGTTGGTTACTGATTTTGATATTACTTCTTTTATTACCCGTTGCAGGTCACACAGACCCTTTATCCTT
TCCCGTTGTTACAATGCAACCTGGAACTAATGGTTCGCAATCTTATAGCATCAATCTGCAAATTTTAATTTTTATGACTT
TATTGACCGTATTGCCAGGGTTGCTGATGGCAATGACGTCATTTACAAGGATAATTATTGTTCTGTCAATTTTACGGCAG
GCAATAGGGATGGCTCAGACGCCTACCAATCAAATATTAATAGGCATTGCTCTATTTATGACTTATTTTGTTATGTCGCC
TGTATTCAACAAAATTAATGAAACAGCAATACAGCCCTATATGAATGAAAGGATTGATTTTTCTCTGGCATTATCCAATG
CGCAAAAGCCGCTTCGTCAGTTTATGCTAAACCAAACAAGAAAAAATGATTTATCTTTATTTGAAAAATTTGCTAACAAT
GTACCAAAAACTTTAGATGAGATTCCTATGAGTGTTCTCATTCCGGCTTTCATTACTAGCGAGTTAAAAACTGCATTTCA
AATAGGCTTTATTCTTTTTTTGCCCTTTTTAATTATTGATCTTGTTGTGTCCAGCCTTTTGATGGCTATGGGGATGATGA
TGCTTTCACCCTTGATTATTTCATTACCTTTTAAAATCATGTTGTTTGTGATGGTTGATGGATGGACTTTGGTTTTGGGT
TCACTTGCTTCAAGTTTTGCTCTTGCCTAG

Protein sequence :

MKIKSWLLILILLLLLPVAGHTDPLSFPVVTMQPGTNGSQSYSINLQILIFMTLLTVLPGLLMAMTSFTRIIIVLSILRQ
AIGMAQTPTNQILIGIALFMTYFVMSPVFNKINETAIQPYMNERIDFSLALSNAQKPLRQFMLNQTRKNDLSLFEKFANN
VPKTLDEIPMSVLIPAFITSELKTAFQIGFILFLPFLIIDLVVSSLLMAMGMMMLSPLIISLPFKIMLFVMVDGWTLVLG
SLASSFALA

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
escR	AFO66317.1	putative LEE-encoded type III secretion system factor	Virulence	SESS LEE	Protein	1e-13	44
escR	AFO66400.1	putative LEE-encoded type III secretion system factor	Virulence	SESS LEE	Protein	1e-13	44
hrcR	ABA47279.1	HrcR	Virulence	S-PAI	Protein	7e-13	42
hrcR	AAT96262.1	HrcR	Virulence	S-PAI	Protein	3e-11	42
hrcR	AAT96303.1	HrcR	Virulence	S-PAI	Protein	3e-11	42
hrcR	AAT96343.1	HrcR	Virulence	S-PAI	Protein	3e-11	42
hrcR	AAP34349.1	HrcR	Virulence	Hrp PAI	Protein	6e-18	41
YPO0270	YP_002345352.1	type III secretion system protein	Virulence	Not named	Protein	2e-14	41
hrcR	AAD21321.1	HrcR	Virulence	Hrp PAI	Protein	3e-18	41
hrcR	NP_640757.1	type III secretion system protein	Virulence	Hrp PAI	Protein	4e-18	41
hrcR	YP_362153.1	type III secretion system protein	Virulence	Hrp PAI	Protein	4e-18	41
escR	AAK26700.1	EscR	Virulence	LEE	Protein	1e-13	41
escR	NP_290283.1	type III secretion system protein	Virulence	LEE	Protein	1e-13	41
escR	AAL57527.1	EscR	Virulence	LEE	Protein	1e-13	41
escR	CAC81847.1	EscR protein	Virulence	LEE II	Protein	1e-13	41
escR	CAI43889.1	EscR protein	Virulence	LEE	Protein	1e-13	41
ECs4583	NP_312610.1	type III secretion system protein	Virulence	LEE	Protein	3e-13	41
escR	YP_003223490.1	T3SS structure protein EscR	Virulence	LEE	Protein	1e-13	41
escR	AAC31528.1	L0049	Virulence	LEE	Protein	9e-14	41
escR	YP_003232138.1	type III secretion system protein	Virulence	LEE	Protein	1e-13	41
escR	ACU09473.1	type III secretion system protein EscR	Virulence	LEE	Protein	9e-14	41
escR	YP_003236103.1	T3SS structure protein EscR	Virulence	LEE	Protein	1e-13	41

• Homologs from VFDB (virulence genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
fliP	YP_006509053.1	flagellar biosynthesis protein	VFG2016	Protein	3e-86	98
fliP	YP_006509053.1	flagellar biosynthesis protein	VFG1259	Protein	7e-47	62
fliP	YP_006509053.1	flagellar biosynthesis protein	VFG2338	Protein	2e-42	56
fliP	YP_006509053.1	flagellar biosynthesis protein	VFG2494	Protein	5e-42	54
fliP	YP_006509053.1	flagellar biosynthesis protein	VFG2131	Protein	2e-16	43
fliP	YP_006509053.1	flagellar biosynthesis protein	VFG0044	Protein	7e-14	42
fliP	YP_006509053.1	flagellar biosynthesis protein	VFG0827	Protein	5e-14	41