Gene Information

Name : fliI (LPV_2026)
Accession : YP_006509021.1
Strain : Legionella pneumophila HL06041035
Genome accession: NC_018140
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 2069085 - 2070434 bp
Length : 1350 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1482109; Product type e : enzyme

DNA sequence :
ATGGCGATTTACCAAACACAACTCCATAAAATTTTGTCAGGAACAAGGAATAAACATCATTCCGGACTGTTACATTGTGG
TAGAATCAGCAGAGCAATAGGTTTAACCATAGAAGCAAAGGGATTTAATCAGCCTGTAGGAGCACGTTGCCTGGTTAAAA
TCAATGATGAACATTCTGTTCAGGCAGAAGTTGTTGGTTTTAGTAATGAAAGTGTTTATTTAATGTCTATTGGAGATATA
CAAGGTATAGCCCCTGGAATGAAAATTATTCCTACCGGACGCATTGCTCAAGTAAATGTTGGCCATCAATTGTTAGGAAG
AGTATTAAATGGTTCCGGAATGTTTATAGACGATGGACCTCCTAGTGAAATGGTTGAGACTTATCCATTGATAGGGCAAG
TGATCAATCCTTTAAAAAGAGCCCCTATTGAAGTCCCATTGGATGTTGGGATTCGCGCTATTAATGGCTTATTAACTGTT
GGCCGTGGACAACGGATAGGTTTGTTCGCTGGAAGTGGAGTTGGCAAATCAGTTTTGCTTGGGATGATGACGCGTTTTAC
TGAAGCTGATGTTGTTGTGGTTGGATTAATTGGAGAACGTGGGCGCGAGGTAAAAGAATTTATTGAGTGCAATTTGGGTC
TGGAAGGTTTGAGGCGAGCGGTTGTAGTTGCCGCTCCAGCGGATGAAAGCCCTTTGATGCGTTTGCACGGCGCGAAGGTT
GCAACAAGCATTGCTGAGTATTTTCGGGATCAAGGTAAACATGTTCTCTTGCTGATTGATTCTTTAACCCGTTTTGCTCA
GGCACAAAGAGAAATCGCGTTATCGATTGGTGAGGCTCCTGCCACAAAAGGATATCCGCCATCGGTATTTGCCAAATTGC
CTAAATTGGTTGAAAGAGCTGGAAATGGGACTTCAGGGGGTGGTTCAATTACGGCATTTTATACTGTTTTGACTGAGGGA
GATGATTTGCAAGATCCCATAGCAGATGCGGCACGAGCTATTTTGGATGGTCATGTTGTATTAAGCAGAGCGCTTGCAGA
GCAAGGGCAGTATCCTGCAATAGATCTTGAAGCTTCTATTAGCCGAGTTATGCAGGGCATTGTCTCTGAACAACATATGA
AAGATATGTTATTGTTTAAAAAATACTTGTCTGTTTATGAAAAAAACAAGGATTTAATTTTATTAGGAGCCTATGCAAAA
GGAAGCGATCCCCTGGTGGATAAAGCGATATTAGCAGTGAATAAACTCAAAGATTACCTAGCGCAAGGAATGGATGAACA
AGTAAGCTACGATGAGAGTTTATTATCGCTATCCAAACTGATTTCAACTTTGGTAGGGAATGACCAATGA

Protein sequence :
MAIYQTQLHKILSGTRNKHHSGLLHCGRISRAIGLTIEAKGFNQPVGARCLVKINDEHSVQAEVVGFSNESVYLMSIGDI
QGIAPGMKIIPTGRIAQVNVGHQLLGRVLNGSGMFIDDGPPSEMVETYPLIGQVINPLKRAPIEVPLDVGIRAINGLLTV
GRGQRIGLFAGSGVGKSVLLGMMTRFTEADVVVVGLIGERGREVKEFIECNLGLEGLRRAVVVAAPADESPLMRLHGAKV
ATSIAEYFRDQGKHVLLLIDSLTRFAQAQREIALSIGEAPATKGYPPSVFAKLPKLVERAGNGTSGGGSITAFYTVLTEG
DDLQDPIADAARAILDGHVVLSRALAEQGQYPAIDLEASISRVMQGIVSEQHMKDMLLFKKYLSVYEKNKDLILLGAYAK
GSDPLVDKAILAVNKLKDYLAQGMDEQVSYDESLLSLSKLISTLVGNDQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-88 49
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-84 48
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 5e-84 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 48
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-84 48
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-84 48
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-84 48
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-84 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-82 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-82 48
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-76 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-72 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-71 46
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-71 46
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-72 46
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-71 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-70 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-67 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 4e-71 45
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-74 45
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-74 45
escN AAC38383.1 EscN Virulence LEE Protein 7e-75 45
escN AAC31513.1 L0034 Virulence LEE Protein 2e-74 45
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-74 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-79 44
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-73 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-74 44
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-74 44
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-68 44
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-68 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 5e-66 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 5e-73 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-73 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 8e-73 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-71 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-71 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-64 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-64 43
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-74 43
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-74 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-74 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-61 43
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-74 43
escN AAK26715.1 EscN Virulence LEE Protein 2e-74 43
escN AAL57542.1 EscN Virulence LEE Protein 2e-74 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-63 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-64 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 6e-64 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-64 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 6e-64 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_006509021.1 flagellum-specific ATP synthase VFG1254 Protein 3e-121 64
fliI YP_006509021.1 flagellum-specific ATP synthase VFG2331 Protein 8e-116 61
fliI YP_006509021.1 flagellum-specific ATP synthase VFG2499 Protein 6e-118 59
fliI YP_006509021.1 flagellum-specific ATP synthase VFG0390 Protein 3e-89 49
fliI YP_006509021.1 flagellum-specific ATP synthase VFG2144 Protein 6e-92 48
fliI YP_006509021.1 flagellum-specific ATP synthase VFG0192 Protein 9e-92 48
fliI YP_006509021.1 flagellum-specific ATP synthase VFG0048 Protein 6e-88 47
fliI YP_006509021.1 flagellum-specific ATP synthase VFG0515 Protein 2e-72 46
fliI YP_006509021.1 flagellum-specific ATP synthase VFG0812 Protein 1e-74 45
fliI YP_006509021.1 flagellum-specific ATP synthase VFG0730 Protein 4e-75 45
fliI YP_006509021.1 flagellum-specific ATP synthase VFG1008 Protein 2e-63 43
fliI YP_006509021.1 flagellum-specific ATP synthase VFG0555 Protein 2e-64 42
fliI YP_006509021.1 flagellum-specific ATP synthase VFG2459 Protein 3e-65 41
fliI YP_006509021.1 flagellum-specific ATP synthase VFG1778 Protein 2e-62 41