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Name : cadA (LPV_0160) Accession : YP_006507311.1 Strain : Legionella pneumophila HL06041035 Genome accession: NC_018140 Putative virulence/resistance : Resistance Product : putative cadmium-transporting ATPase (Cadmium efflux ATPase) Function : - COG functional category : - COG ID : - EC number : 3.6.3.3 Position : 177675 - 179582 bp Length : 1908 bp Strand : + Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology DNA sequence : ATGGGCTGCTGCACATGCTCTTCACATAAAGAACCAATGCCAAAGCTATGGCATAATCCCAAAGTCATTACAGCAACTAT AGCTGGTTTATTATTAACTGTTGGTTTTGTAGGCTCATATTTGGCATTACCAATGATTATCGCTAATGGGTTTTACATAG GCGCAGTATTAATTGGCGGATATTATTTCGCTCGCGAAGCAATAGACGAATTTATCAAAGAATATGAAATCGGTATTGAA TTCTTGATGTCTCTTGCTGCCATTGTTGCCGGTGTCATGGGACAATGGGCGGAAGCAGCAACATTGGTATTTTTGTATTC TATTTCTGAAGCTGCGGAAGGTTATTCCGGTGAAAGAGCGCGACATGCTATCCGAGCATTGATGGATCTTGCCCCAAAAA CAGCATTGGTCCGGCGAAATAATACTGAATTTCGAATACCCATAGAAGAAATTCATATTGGAGATGAATTCATTGTTCTT CCTGGTGAAAGTCTTGCCACAGATGGAGAAGTCATTTCAGGACATTCTAGTGTTAATCAAGCACCTATTACGGGTGAGTC AATTCCAGTAGAAAAAACTATAGGGAGTAAAGTTTTTTCTGCAACTATAAACGGTGAAGGAACTCTTACTGTTCGTGCAA CCAAAAAATTTGCTGATAATACATTATCTCGTATCATATTTCTTGTCGAAAAAGCACAAGACAAAAAGGGGCGTAGTCAA CGTTTTATAGAACGTTTTGGTAACCTATATAGTCCATTTATCCTTTTGGTGGGAATACTCATAGCTACTTTACCACCTCT ATTTGGGCAACCTTGGCAAGAGTGGGTGATTCGTGCCACAGTATTTATTGTTGCTGCAGCACCATGTGCCCTAGTGATTT CTATACCCATTACACTTGTAGCTGCTCTTGGCACAGCAAGTCGAAATGGAATATTACTAAAAGGTGGCTTATATTTGGAG CAACTAGTGAAGATAAAGGTTATTGCACTAGATAAAACAGGAACATTAACACAAGGTAAACCGAAGGTTACTGATATCAT TCCATTGAATAACCATACTCGGAACCAAATTTTAAATGCAGCAGCAACTCTTGAATCGCGTTCCCAGCATCCCATGGCCC AAGCCATTTTGCAACAAGCCAATGAAGAAAATATTCAATATAATCCTGTTGAACAGTTTAAGTCATTAACTGGTTCAGGT GTACTTGGTTTTATCAATGGGGAAAAATTCTACATAGGCAATCCAAAATTATTTATTGATATGGGCCTATTGATAGAAAC ATTAACACAGGAAATAAATAAATTACAGGCCGCTGGAAAGACAGTCGTATTATTAGGAACTGATAAGGAAATCCTCGGTT TAATTGCAATTGCTGATCCTCTAAGACCAACAGCCAGGCAGATGGTGTCTAACTTAAAATCGATGGGTATTGAACGTGTG GTTATGCTCACAGGAGATAATTTGATAACTGCCTCCTCAATTGGCGAACAAGCGGGTGTTGATGAAGTATTTTCTGATTT ATCACCAGAAGATAAGACACGAAAAATTGAAGAGTTAGAAAGACGTTATGGTAAGGTAATGATGGTTGGTGATGGAGTAA ATGATGCTCCAGCACTCGCAGCAGCTCATGTAGGAGTTGCTATGGGAGCTGTCGGAACCGATGTTGCATTAGAAACTGCG GATGTAGCCTTAATGGGTGATAATTTATTAAAATTACCTTATCTTATCGCATTTAGTCGTCGAACCTGGAATATAATTTT ACAAAACTTGGGACTTTCTATAATTGTAATTAGCTCTCTTGTTGTCGGTGCAATAACAGGTTATTTCACGTTGCCGATAG CAGTTTTAGCTCATGAAATCAGTGAGCTTATTGTTATTGCAAGTGGTCTTCGTATGTTAAAGTCTTAG Protein sequence : MGCCTCSSHKEPMPKLWHNPKVITATIAGLLLTVGFVGSYLALPMIIANGFYIGAVLIGGYYFAREAIDEFIKEYEIGIE FLMSLAAIVAGVMGQWAEAATLVFLYSISEAAEGYSGERARHAIRALMDLAPKTALVRRNNTEFRIPIEEIHIGDEFIVL PGESLATDGEVISGHSSVNQAPITGESIPVEKTIGSKVFSATINGEGTLTVRATKKFADNTLSRIIFLVEKAQDKKGRSQ RFIERFGNLYSPFILLVGILIATLPPLFGQPWQEWVIRATVFIVAAAPCALVISIPITLVAALGTASRNGILLKGGLYLE QLVKIKVIALDKTGTLTQGKPKVTDIIPLNNHTRNQILNAAATLESRSQHPMAQAILQQANEENIQYNPVEQFKSLTGSG VLGFINGEKFYIGNPKLFIDMGLLIETLTQEINKLQAAGKTVVLLGTDKEILGLIAIADPLRPTARQMVSNLKSMGIERV VMLTGDNLITASSIGEQAGVDEVFSDLSPEDKTRKIEELERRYGKVMMVGDGVNDAPALAAAHVGVAMGAVGTDVALETA DVALMGDNLLKLPYLIAFSRRTWNIILQNLGLSIIVISSLVVGAITGYFTLPIAVLAHEISELIVIASGLRMLKS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SE0075 | NP_763630.1 | cadmium resistance protein B | Not tested | SCCpbp4 | Protein | 3e-122 | 46 |
| unnamed | BAB47609.1 | cadmium resistance protein B | Not tested | Type-III SCCmec | Protein | 3e-120 | 45 |
| cadA | BAC57487.1 | Probable cadmium-transporting ATPase (Cadmium efflux ATPase) | Not tested | Type-IIIinv SCCmec | Protein | 3e-120 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| cadA | YP_006507311.1 | putative cadmium-transporting ATPase (Cadmium efflux ATPase) | BAC0298 | Protein | 3e-94 | 44 |
| cadA | YP_006507311.1 | putative cadmium-transporting ATPase (Cadmium efflux ATPase) | BAC0092 | Protein | 3e-101 | 43 |
| cadA | YP_006507311.1 | putative cadmium-transporting ATPase (Cadmium efflux ATPase) | BAC0100 | Protein | 4e-89 | 43 |
| cadA | YP_006507311.1 | putative cadmium-transporting ATPase (Cadmium efflux ATPase) | BAC0124 | Protein | 2e-86 | 41 |
