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Name : cadA (LPV_1197) Accession : YP_006508265.1 Strain : Legionella pneumophila HL06041035 Genome accession: NC_018140 Putative virulence/resistance : Resistance Product : zinc, cobalt and lead efflux system Function : - COG functional category : - COG ID : - EC number : 3.6.3.3 Position : 1207350 - 1209599 bp Length : 2250 bp Strand : + Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10660539, 12746428, 21305696, 9364914, 9405611, 98070750, 99428388; Product type t : transporter DNA sequence : TTGGGGTCGTTATTCGGTGAGCCATGCTTCGATAGGAATGAATTGTCTGCGATGTCGAACTTCTCTTGCTCCGGGGGCAT ATTTTTACAGTCAATGTGGGAAATCATGATGACAGCTCCGCTCACCTTAACCACTTTTTTTGTTGCAGGACTTGATTGTC AGGCTGAAGAACAATTAATCAGGCGGCAATTGCAAGCTATCCCTGAAGTGGAAAAGATGGATTTTAATTTTATTGCTGAA GAAGTAACGGTTCATCATCGATTACCCACCATTGAACCTATACAACAGCAGATAGAAGCCTTAGGGATGAGCGTGCGCGC CAAACAAAGCACCCCTAGCGACAAGGTTCAGGAAAAACTTAAATTTGATGCCTCTTGGCAGATTCTTGCATTATCAGGTC TATTGGCTCTTTGCTCCGAAATAGCAGCTTATCTTTTGGCAACAGAGCAATCTCTATGGGCCATTATTCCTGCCTTACTG GCCATTATTCTCAGTGGACCTCCTACTTTTAAAAAAGGTTGGCTTGCTTTGCGCACAAAAGCCATGAACATTAACAGTCT AATGCTCATTGCCATAACAGGGGCTATCTTTATCGGTGATTGGCCTGAGGCGGCTATGGTTACTGTTTTGTTTGCATTGG CGGAACGAATAGAGCGTTATTCCTTAGACAAAGCACGTCTGGCTATTCGAAGCTTGATGCAGATTGTTCCTGATGTGGCT CAAGTGAAAACAGCTAATGGTCAATGGCAAACTTTACTGGTCGAGGAAGTGCCACTGGGTGCTGTTTTTAGAGTTAAGCC TGGTGAGCGTATTCCATTGGATGGTGAGGTGGTTTCAGGTCAAAGTACAGTCAACCAAGCTCCTATTACCGGGGAATCCA TGCCAGTGAGTAAGCAGATAGGTGATTCTGTTTTTGCCGGCTCTTTAAATGAGCATGGGGCTTTTGAAGCGAAGGTGAGC AAAGCGTCAGGCGATACGCTGCTCGCTAAAATTGGTAAAGCGATTGAACAGGCGCAAGCTGAGCGGGCCCCAACGCAACG ATTTGTTGACGAATTTGCAAGATACTATACGCCTATTATGGTATTGATTGCTGTTCTTGTCGCTTTAATTCCTCCTTTCG TGTTGGGATATTCTTTTTATGATTGGATCTATAAGGCGTTGACTTTATTAGTTATTGCCTGTCCTTGTGCCCTGGTCATT TCAACACCAGTAACAGTGGTGAGTGGCTTGGCTGCCTCTGCCAAACATGGGCTTCTCATCAAAGGAGGAAGCTATTTAGA GACGGGTTATCGCTTACAGTTAATTGCACTGGATAAAACTGGTACCTTAACAGAGGGCAAACCGGTGGTAACCGATTTTA TTACTTATGATAAAAGTCAAACCAATGAACACTTGTTGTTGCTTGCTGCAAGTCTTGACAGCCACTCCGAGCACCCCGTA GCTCATGCCCTAGTGGCATATTGGCAGCAAGAGCATCCTGATAAATCATTGCTTTCAGTGGAACGGTTTTCAGCGCTTCC TGGGCGAGGCGTGAAAGGTGCCATCCAGGGGGAATTGTATTATGTAGGCAATCATCAATTAGCAGAAGACAACAAAGTCT GTTGTTTAGAGGTTGAGCAAGAATTGAAACGACTGGAAGAAGAAGGAAAAACTACTGTTATATTAAGCAATAGCACTACG GTCTTGGCTATTTTTGCAGTGGCAGATACGCTTCGAGCCAACAGTCGAGAGGCGATTGAATCATTGCATCGACAAAGGAT AAAAACGGCGATGTTAACAGGTGATAATGCTCTAACCGCTCAAGCCATTGCCAAACAAGTCGGCATTGATGAAATCCAAG CTAATATATTACCAACAGAAAAAATGCAGGCTATCAATAAACTCTTAGAACAATATCAGGCTGTGGGCATGGTGGGAGAT GGCATTAATGATGCACCTGCTTTAGCGAAAGCCACTATTAGCTTTGCGATGGGCAAGGGAACAGATACCGCTTTAGAGAC AGCGGATGTGGTATTAATGAATGATAATTTAGCCATGCTTCCTCTGTACATTGACTTAAGCCGGAAGACAGTGCGAATTT TATGGCAAAACATTAGTCTATCCTTGGTTATTAAAACGGTGTTTTTTATTTTAGCACTTGGAGGAATGGCTACCCTTTGG ATGGCGGTTTTTGCTGACATGGGGGCTAGTTTGATTGTGGTTATGAATGGGCTACGATTGTTGAATTCAAATCAAACGAA GAATCATTAA Protein sequence : MGSLFGEPCFDRNELSAMSNFSCSGGIFLQSMWEIMMTAPLTLTTFFVAGLDCQAEEQLIRRQLQAIPEVEKMDFNFIAE EVTVHHRLPTIEPIQQQIEALGMSVRAKQSTPSDKVQEKLKFDASWQILALSGLLALCSEIAAYLLATEQSLWAIIPALL AIILSGPPTFKKGWLALRTKAMNINSLMLIAITGAIFIGDWPEAAMVTVLFALAERIERYSLDKARLAIRSLMQIVPDVA QVKTANGQWQTLLVEEVPLGAVFRVKPGERIPLDGEVVSGQSTVNQAPITGESMPVSKQIGDSVFAGSLNEHGAFEAKVS KASGDTLLAKIGKAIEQAQAERAPTQRFVDEFARYYTPIMVLIAVLVALIPPFVLGYSFYDWIYKALTLLVIACPCALVI STPVTVVSGLAASAKHGLLIKGGSYLETGYRLQLIALDKTGTLTEGKPVVTDFITYDKSQTNEHLLLLAASLDSHSEHPV AHALVAYWQQEHPDKSLLSVERFSALPGRGVKGAIQGELYYVGNHQLAEDNKVCCLEVEQELKRLEEEGKTTVILSNSTT VLAIFAVADTLRANSREAIESLHRQRIKTAMLTGDNALTAQAIAKQVGIDEIQANILPTEKMQAINKLLEQYQAVGMVGD GINDAPALAKATISFAMGKGTDTALETADVVLMNDNLAMLPLYIDLSRKTVRILWQNISLSLVIKTVFFILALGGMATLW MAVFADMGASLIVVMNGLRLLNSNQTKNH |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ORF C97 | AAN62190.1 | putative metal-transporting P-type ATPase | Not tested | PAGI-2(C) | Protein | 1e-153 | 51 |
| SE0075 | NP_763630.1 | cadmium resistance protein B | Not tested | SCCpbp4 | Protein | 8e-119 | 41 |
| cadA | BAC57487.1 | Probable cadmium-transporting ATPase (Cadmium efflux ATPase) | Not tested | Type-IIIinv SCCmec | Protein | 3e-116 | 41 |
| unnamed | BAB47609.1 | cadmium resistance protein B | Not tested | Type-III SCCmec | Protein | 3e-116 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| cadA | YP_006508265.1 | zinc, cobalt and lead efflux system | BAC0298 | Protein | 2e-148 | 52 |
| cadA | YP_006508265.1 | zinc, cobalt and lead efflux system | BAC0461 | Protein | 4e-77 | 41 |
