Gene Information

Name : hemC (LPO_3022)
Accession : YP_006506868.1
Strain : Legionella pneumophila Lorraine
Genome accession: NC_018139
Putative virulence/resistance : Unknown
Product : hydroxymethylbilane synthase
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.61
Position : 3144062 - 3144991 bp
Length : 930 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1522882, 1747120, 2025226, 2122889, 2510713, 3052434, 3054815, 3196304, 3529035, 8874804, 90056403, 93170293; Product type e : enzyme

DNA sequence : 
ATGAGCGCAAAAATTATACGAATCGCAACGAGGCAGAGCCCGCTTGCACTATGGCAGGCTAATCATGTACGGGAAATGCT
TGTAAAGCAATGGCCAAATCTAAGCATTGAATTATTACCTATGATAACCTCTGGCGATCGGTTTCTTAAAGATAAATTAT
TATCCGCAGGAGGAAAAGGGTTATTTGTTAAAGAGTTAGAAGAAGCATTATTGGATAAAAGAGCGGACTTGGCTGTTCAT
TCGACCAAAGACATGCCAGCACAACTTCCGGATGGCCTCTCGTTGGCCGCCATTTGCAAAAGAGATAACCCTTTTGACGC
TTTAATAAGTCCCCAATTTAAGAGTCTGGATGCTCTCCCCAAAAACGCAATTATTGGTACATCAAGTCTTAGACGTCAAT
CTCAACTATTGGCTTACAATCCCAATTTGCAAATCAAAACATTAAGAGGAAACATCCATACAAGACTCAGCAAACTGGAG
TCAGGAGAGTATCAAGCCATTATTCTTGCTGCCGCAGGCTTGGAAAGAATGGGCTTGGCACATCACATCACCCAACTCAT
ACCCGATGACATTATGCTGCCTACTTGTGCTCAGGGCGCTTTATGTATTGAGTGCCGAACTGACGATTTGGAAATCCAGG
AGCTGATTCATGGCTTAAATGATCCAATTTCTGCCCTTTGTGTTCATACCGAGCGACGCGTCAACGCAAAACTAGGAGGC
AATTGCCATATACCCTTTGCTGTTTATTGTACCATTACTGCGGAGAACCTCCTCCTTTTGAGAGCAAAAGTACTTAATCT
GGATGGTTCTCAAATGATTGATGATGAGCAACAAGGGAAAATAGAAGAAGCTGAAATTATTGCAGACAGGTGTACCGAGT
CATTAATGACAAAAGGTGCGATGACCTTACTGAGCACGATACCATCATGA

Protein sequence : 
MSAKIIRIATRQSPLALWQANHVREMLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKGLFVKELEEALLDKRADLAVH
STKDMPAQLPDGLSLAAICKRDNPFDALISPQFKSLDALPKNAIIGTSSLRRQSQLLAYNPNLQIKTLRGNIHTRLSKLE
SGEYQAIILAAAGLERMGLAHHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELIHGLNDPISALCVHTERRVNAKLGG
NCHIPFAVYCTITAENLLLLRAKVLNLDGSQMIDDEQQGKIEEAEIIADRCTESLMTKGAMTLLSTIPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-67 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-67 49