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Name : betB (LPO_0277) Accession : YP_006504343.1 Strain : Legionella pneumophila Lorraine Genome accession: NC_018139 Putative virulence/resistance : Virulence Product : betaine aldehyde dehydrogenase, NAD-dependent Function : - COG functional category : - COG ID : - EC number : 1.2.1.8 Position : 296600 - 298066 bp Length : 1467 bp Strand : + Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1879697, 89124888, 90304165, 92065800; Product type e : enzyme DNA sequence : ATGGAAATTTACGAAATGTACATTGATGGAAAATTTACTTTAGCCAAAAGCGGAACTACTCGCGACATTTTTGATCCGGC TAACGGGGAATTGATTGCAAGAGTGCCAGAAAGTGCCAAAGAAGATGCCATACTTGCTATCAAAGCAGCGAGAAAAGCCT TCGATGAAGGAGAGTGGAGAAAATCACTGGCGCTTGATCGAGGCAAATTGTTATTCAAGCTTGCTGATTTGATTCGAGCC AATGCTAAAATGTTGGCAGAGCTGGAAACTAGAAATTGCGGAAAGCCGTTACCCGAGGCGGAGTTTGATGTCACTGATGC TGCCAATTGCTTTGAATTTTATGGTGGGCTTGCGACTAAAATTCATGGTGAAACGATGTCGGTCCCAGCGAATTCATTTA GTTACGTAGTTCGTGAACCCATAGGCGTGTGTGGGCAAATCATTCCATGGAATTTTCCACTGCTTATGGCGGCCTGGAAG CTTGCACCCGCACTTGCCGCAGGCAATACCGTGGTATTAAAACCATCAGAATTGACCCCGACAACGGCACTTGAGTTATT CAAGTTGATTGATCAATGCGGATTTCCCGCGGGCGTGGTTAACCTCATTACTGGGCCGGGTATAGGAGTTGGAGAGGAGT TGGCAAGTAATTCTATGGTGGATAAGGTTGCTTTCACCGGAGGATCGGCAACAGGCAGAAAAATCATACAGGCAGCTACT GGCAATTTGAAAAAAATCTCGTTAGAGCTTGGCGGAAAAAATCCAAATATTGTCTTTGCAGACTGTGACCTTGAAATGGC AATCGACGGTGCCCTTTTTGGTGCTTTTGCAAATCAAGGGGAAGTCTGTTCTGCGGGTTCCCGCTTGCTAGTGGAGCGCT CTATTCACAAAAAAATAGTAGAGGGAATGTTGAAAAAAATTCCAAATATCAAGCTTGGCCATGGTTTGGACGCTGGGGTA AAAATGGGGCCTTTGGTTTCAAGTGCACATCGAGAAAAAGTGGAAGGCTATGTCAAGCTTGGAATGGAAGAAGGGGCCAA ATTACTTTGCGGCGGTAAACGCCCGACAGGCAGTGAATTTGCAAAGGGACATTTTTTCGAGCCAACCATTTTTGATGAAG TGAAATCCACGATGCGTATTGCTCGTGAAGAAATTTTTGGTCCAGTACTTGTGGTCATCCCTTTTGATACAGAAGAAGAA GCCATTCGCATTGCGAACGATACTGATTATGGTTTATCCGGGGCTGTATGGACGAAGAGTGTTACTCGGGCCCATCGAGT CACATCTCAAATCCGTGCCGGGATTCTTTGGGTGAATCATTACCATCCAACCTATAATGAAATGCCTTGGGGCGGATACA AACAAAGTGGAGCGGGTCGTGAGTTAGGCTTGTATGGCATTGAGAGTTACCTTGAGGTCAAGCAAGTGAATATTAACCTG GATGAAACACCAATTGGTTGGTACTAA Protein sequence : MEIYEMYIDGKFTLAKSGTTRDIFDPANGELIARVPESAKEDAILAIKAARKAFDEGEWRKSLALDRGKLLFKLADLIRA NAKMLAELETRNCGKPLPEAEFDVTDAANCFEFYGGLATKIHGETMSVPANSFSYVVREPIGVCGQIIPWNFPLLMAAWK LAPALAAGNTVVLKPSELTPTTALELFKLIDQCGFPAGVVNLITGPGIGVGEELASNSMVDKVAFTGGSATGRKIIQAAT GNLKKISLELGGKNPNIVFADCDLEMAIDGALFGAFANQGEVCSAGSRLLVERSIHKKIVEGMLKKIPNIKLGHGLDAGV KMGPLVSSAHREKVEGYVKLGMEEGAKLLCGGKRPTGSEFAKGHFFEPTIFDEVKSTMRIAREEIFGPVLVVIPFDTEEE AIRIANDTDYGLSGAVWTKSVTRAHRVTSQIRAGILWVNHYHPTYNEMPWGGYKQSGAGRELGLYGIESYLEVKQVNINL DETPIGWY |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 2e-76 | 44 |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 3e-71 | 42 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-73 | 41 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-73 | 41 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-73 | 41 |
| aldA | ACK75585.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 1e-42 | 41 |
| aldA | ACK75593.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 1e-42 | 41 |
| aldA | ACK75574.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 5e-43 | 41 |
| aldA | ACK75590.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 5e-43 | 41 |
| aldA | ACK75596.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 5e-43 | 41 |
| aldA | ACK75588.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 6e-42 | 41 |
| aldA | ACK75577.1 | aldehyde dehydrogenase | Not tested | VPI | Protein | 1e-42 | 41 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 4e-73 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| betB | YP_006504343.1 | betaine aldehyde dehydrogenase, NAD-dependent | VFG0082 | Protein | 1e-71 | 42 |
