Gene Information

Name : fliI (LPO_1802)
Accession : YP_006505749.1
Strain : Legionella pneumophila Lorraine
Genome accession: NC_018139
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 1864369 - 1865718 bp
Length : 1350 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1482109; Product type e : enzyme

DNA sequence :
ATGGCTATTTACCAAACACAACTCCATAAAATTTTGTCAGGAACAAGGAATAAACATCATTCCGGGTTGTTACATTGTGG
TAGAATCAGCAGAGCAATAGGTTTAACCATAGAAGCAAAAGGATTTAATCAGCCCATAGGAGCGCGTTGTCTGGTTAAAA
TCAATGATGAACATTCTGTTCAGGCAGAAGTTGTTGGTTTTAGTAATGAAAGTGTCTATTTAATGTCTATTGGAGATATA
CAAGGTATAGCCCCAGGAATGAAAATTATTCCTACCGGACGCATTGCTCAAGTAAATGTCGGCCATCAACTGTTAGGAAG
AATATTAAATGGTTCCGGAATGTTTATAGACGATGGACCCCCTGGTGAAATGGTTGAGACTTATCCATTGATAGGACAAG
TAATCAATCCTTTAAAAAGAGCCCCTATTGAAGTCCCATTGGATGTTGGGATTCGTGCTATTAATGGCTTATTAACTGTT
GGCCGTGGACAAAGGATAGGTTTGTTCGCTGGAAGTGGAGTTGGCAAATCAGTTTTGCTTGGGATGATGACGCGTTTTAC
TGAAGCTGATGTTGTTGTGGTTGGATTAATTGGAGAACGTGGGCGCGAGGTAAAAGAATTTATTGAGTGCAACTTGGGTC
TGGAAGGTTTGAAGCGAGCGGTTGTAGTTGCCGCTCCAGCCGATGAAAGCCCGTTGATGCGTTTGCACGGAGCGAAGGTT
GCAACAAGCATTGCTGAGTATTTTCGGGACCAAGGCAAACATGTTCTCTTGCTGATTGATTCTTTAACCCGTTTTGCCCA
GGCACAAAGGGAAATCGCGTTATCGATTGGTGAAGCCCCTGCTACAAAAGGATATCCGCCATCGGTATTTGCCAAATTGC
CTAAATTGGTTGAAAGAGCTGGAAATGGGACTTCGGGGGGTGGTTCAATTACAGCATTTTATACTGTCTTGACTGAGGGA
GACGATTTGCAGGATCCCATAGCAGATGCGGCACGAGCTATTTTGGATGGTCATGTTGTATTAAGCAGAGCGCTTGCAGA
GCAAGGACAGTATCCTGCAATAGATCTTGAAGCTTCTATTAGCCGAGTTATGCAGGGTGTTGTCTCTGAACAACATATGA
AAGATATGTTATTGTTTAAAAAATACTTGTCTGTTTATGAAAAAAACAAGGATTTAATTTTATTAGGGGCCTATGCAAAA
GGAAGCGATCCTCTGGTGGATAAAGCGATATTAGCAGTGAATAAACTCAAAGATTACCTGGCGCAAGGAATGGATGAACA
AGTAAGCTACAGTGAGAGTTTATTATCGTTATCCAAACTGATTTCAACTTTGGTAGGGAATGACCAATGA

Protein sequence :
MAIYQTQLHKILSGTRNKHHSGLLHCGRISRAIGLTIEAKGFNQPIGARCLVKINDEHSVQAEVVGFSNESVYLMSIGDI
QGIAPGMKIIPTGRIAQVNVGHQLLGRILNGSGMFIDDGPPGEMVETYPLIGQVINPLKRAPIEVPLDVGIRAINGLLTV
GRGQRIGLFAGSGVGKSVLLGMMTRFTEADVVVVGLIGERGREVKEFIECNLGLEGLKRAVVVAAPADESPLMRLHGAKV
ATSIAEYFRDQGKHVLLLIDSLTRFAQAQREIALSIGEAPATKGYPPSVFAKLPKLVERAGNGTSGGGSITAFYTVLTEG
DDLQDPIADAARAILDGHVVLSRALAEQGQYPAIDLEASISRVMQGVVSEQHMKDMLLFKKYLSVYEKNKDLILLGAYAK
GSDPLVDKAILAVNKLKDYLAQGMDEQVSYSESLLSLSKLISTLVGNDQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-88 49
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-83 48
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-83 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-82 48
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 48
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 9e-83 48
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-83 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-83 48
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-76 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-81 47
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-81 47
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 9e-72 46
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-72 46
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-72 46
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-72 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-71 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-67 45
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-72 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-73 45
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-73 45
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-73 45
escN AAC38383.1 EscN Virulence LEE Protein 8e-74 45
escN AAC31513.1 L0034 Virulence LEE Protein 2e-73 45
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-73 45
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 8e-68 45
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 8e-68 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 4e-69 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 7e-78 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 4e-70 44
escN AAK26715.1 EscN Virulence LEE Protein 2e-73 44
escN AAL57542.1 EscN Virulence LEE Protein 2e-73 44
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-73 44
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-73 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-73 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-65 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 9e-72 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 5e-72 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-72 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-70 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-70 43
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-73 43
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-73 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-63 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 8e-61 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-63 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-63 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-63 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-63 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-63 42
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-63 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_006505749.1 flagellum-specific ATP synthase VFG1254 Protein 2e-121 65
fliI YP_006505749.1 flagellum-specific ATP synthase VFG2331 Protein 5e-114 62
fliI YP_006505749.1 flagellum-specific ATP synthase VFG2499 Protein 2e-117 59
fliI YP_006505749.1 flagellum-specific ATP synthase VFG0390 Protein 5e-88 49
fliI YP_006505749.1 flagellum-specific ATP synthase VFG0048 Protein 6e-87 48
fliI YP_006505749.1 flagellum-specific ATP synthase VFG0192 Protein 3e-90 48
fliI YP_006505749.1 flagellum-specific ATP synthase VFG2144 Protein 6e-90 47
fliI YP_006505749.1 flagellum-specific ATP synthase VFG0515 Protein 1e-72 46
fliI YP_006505749.1 flagellum-specific ATP synthase VFG0812 Protein 1e-73 45
fliI YP_006505749.1 flagellum-specific ATP synthase VFG0730 Protein 5e-74 45
fliI YP_006505749.1 flagellum-specific ATP synthase VFG1008 Protein 5e-63 44
fliI YP_006505749.1 flagellum-specific ATP synthase VFG0555 Protein 1e-63 43
fliI YP_006505749.1 flagellum-specific ATP synthase VFG1778 Protein 4e-62 42
fliI YP_006505749.1 flagellum-specific ATP synthase VFG2459 Protein 7e-64 42