Gene Information

Name : guaA (LPO_1761)
Accession : YP_006505711.1
Strain : Legionella pneumophila Lorraine
Genome accession: NC_018139
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1819460 - 1821037 bp
Length : 1578 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2982857, 3894345, 85261223, 8548458; Product type e : enzyme

DNA sequence :
ATGAATGATTTGAAAAAAAGCCCATTATTAATATTAGATTTTGGTTCTCAATACACCCAATTAATTGCAAGACGCGTTCG
AGAAATGGGGGTTTATTGTGAAATTTATCCTTATCATATTAATCATGAACAATTTAAAAAATTAAATCCTTGTGGTGTGA
TTTTATCAGGAGGTCCTTCCACAGTAACGCATGATGCCAATCCCAGAGCTCCTCAATGGCTGTTTGAGAGCGATTTACCA
TTGCTGGGTATATGCTATGGGATGCAAACCATGGCTGTACAACTCGGTGGCCAAGTGCATTCATCGGCGTTAAGAGAATT
TGGATATGCTGAGTTGCGTTTGCATGGCCATAGTCAATTATTAAGTAATATCGAAGATCGTACCGCGGTGGATGGCAGTG
CTCTACTGGATGTATGGATGAGCCATGGTGATAAAGTCACTGAGTTACCGCCAGGTTTTAAAGTGATATGTGAAACACGT
AATGCACCAATTGCAGGTATGGCTGATGAAAGTCGTCAAATGTATGGTTTGCAATTTCATCCAGAAGTTACTCATACCTT
GCAAGGTTTAAGAATTTTACAACGTTTTGTCGTAGATATTTGTAAAGCACCAACAGAGTGGACTCCAGAGCATATTATTG
ATGAAGCCATTAATAAAATCAGAGAACAGGTAGGAACTGAAAAAGTTTTACTGGGACTATCCGGAGGCGTTGACTCTTCT
GTTGTAGCCGCATTACTTCATAGAGCCATTGGAGAGCAACTGGTTTGTGTTTTTGTTGATACGGGTTTACTCAGACTTAA
TGAGGCGGAGCAAGTGCTGAGCATGTTCGGTCGGCATATGGGAATACGCATTATTGCAGTCAATGCCGAAGATAAATTTT
TAACTGCTTTGAAGGGAGTAACTTGCCCAGAGGAAAAGAGAAAAATTATTGGGCGTACATTTATCGAAGTCTTTGATGAG
GAAGCACAGAAGCTGACTGATATAAAGTGGCTGGCTCAGGGCACAATCTACCCCGATGTCATCGAGTCTGCAGCAACAAG
TACTAATGATGCGGCTGTGGTCATAAAGTCTCATCATAATGTCGGTGGCTTACCAGATACATTAAATCTTAAACTGCTGG
AGCCTATTCGTGAGCTCTTTAAAGATGAAGTACGTCAAGTAGGTCTGGAATTGGGACTCCCGCATGATATGGTCTATCGA
CATCCCTTTCCTGGACCTGGATTGGGTGTAAGAATTTTAGCGGAAGTAAAAAAAGAATATGCGGACATATTACGTAAGGC
CGATGCTATTTTTATTGAAGAACTGCATAACGCGCAGCTTTATCATAAAATCAGCCAGGCATTTGCTGTTTTTTTACCAG
TAAAGAGCGTTGGTGTGATGGGGGATGGGCGCCGATACGATTACGTAATTTGTTTAAGAGCTGTTGAGACAGTTGATTTT
ATGACAGCACATTGGTCTCAATTGCCCTGGGATTTTTTAGGAAAAGTATCCAATCGAATTATTAATGAAGTAGAGGGAGT
ATCACGTGTCACTTACGATATTTCTGGCAAGCCACCTGCTACCATTGAATGGGAATGA

Protein sequence :
MNDLKKSPLLILDFGSQYTQLIARRVREMGVYCEIYPYHINHEQFKKLNPCGVILSGGPSTVTHDANPRAPQWLFESDLP
LLGICYGMQTMAVQLGGQVHSSALREFGYAELRLHGHSQLLSNIEDRTAVDGSALLDVWMSHGDKVTELPPGFKVICETR
NAPIAGMADESRQMYGLQFHPEVTHTLQGLRILQRFVVDICKAPTEWTPEHIIDEAINKIREQVGTEKVLLGLSGGVDSS
VVAALLHRAIGEQLVCVFVDTGLLRLNEAEQVLSMFGRHMGIRIIAVNAEDKFLTALKGVTCPEEKRKIIGRTFIEVFDE
EAQKLTDIKWLAQGTIYPDVIESAATSTNDAAVVIKSHHNVGGLPDTLNLKLLEPIRELFKDEVRQVGLELGLPHDMVYR
HPFPGPGLGVRILAEVKKEYADILRKADAIFIEELHNAQLYHKISQAFAVFLPVKSVGVMGDGRRYDYVICLRAVETVDF
MTAHWSQLPWDFLGKVSNRIINEVEGVSRVTYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-124 49
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-124 49
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-124 49
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-112 48