Gene Information

Name : A225_0566 (A225_0566)
Accession : YP_006496338.1
Strain : Klebsiella oxytoca E718
Genome accession: NC_018106
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 593131 - 594402 bp
Length : 1272 bp
Strand : +
Note : -

DNA sequence :
ATGGCCTTAACGGATACTAAAGTTCGTTCTGCGAAACCTGAGGAGAAAGAGTATTCACTTGTTGACGGCGACGGTATGTC
CTTACTTGTAAAACCTAACGGCTCAAAGTATTGGCGATTTCGTTTCCGTTTTGGCGGTAAACAACATTTGATGGCGTTCG
GTGTCTATCCTGAAATCTCGTTAGCTAATGCCAGAAAAAAGAGAGAAGAGGCTAGAAAGCTGGTTGCTGCTGGCATTGAT
CCTCGTGAGCATAAGCGTGCTTTAAAAGAAGAGCAGGCGAAAGAGATTATTACTTTCGAGAAGGTTGCCAGAGAATGGCT
TGCGACTAACCAAAAATGGTCGGAAGATCATGCTAATCGCGTAAAAAAGAGCCTGGAGGACAATATCTTCCCGGCAATTG
GTACTTGCAACATTGCTGAACTGGGTACTCGTGATTTACTGGCACCAATTAAAGCAGTGGAAGTGTCTGGACGTCTTGAG
GTGGCTTCTCGTCTCCAACAGCGCACCACGGCCATCATGCGTTATGCAGTACAAAGCGGGCTGATTGATTACAACCCAGC
GCAGGAGATGGCTGGAGCCGTCGCCTCTGGCAATCGACAACATCGTCCGGCGCTGGAATTAAAGCGTATCCCTGAGTTAC
TCGAGAAAATAGACGGTTATACCGGCAGGCCGCTAACCCGCTGGGCAACGGAACTTACTCTGCTTATCTTTATTCGCTCC
AGTGAGCTGCGTTTTGCTCGCTGGTCAGAGATCGATTTTGAAACGTCAATGTGGACCATCCCGCCTGAGCGAGAGCCTAT
TCCCGGCGTGAAACATTCTCAGCGAGGATCAAAGATGCGTACACCTCATCTGGTGCCGCTATCAAAGCAGGCGCTGGCGA
TCCTGAAGCAGATAAAACAGTTCTGTGGTGAACATGAGCTGATTTTTATTGGCGATCACGATCCGCGTAAACCCATGAGT
GAGAACACGGTAAATAGTGCGCTACGGGTTATGGGCTATGACACTAAAGTTGAGGTTTGCGGCCACGGCTTCCGCACAAT
GGCCTGTAGTTCGTTAATTGAGTCAGGTCTATGGTCGAAGGATGCGGTGGAGCGCCAGATGAGCCATATGGAACGTAATT
CGGTACGCGCAGCATATATCCATAAAGCGGAACATCTGGATGAACGCAAGTTGATGCTGCAATGGTGGGCAAACTTCCTG
GATGCAAATCGGGAGAAGAGTATTAGTCCTTTCGATTTTGCGAAAATTAATAATCCCATGCTGACCAGATAA

Protein sequence :
MALTDTKVRSAKPEEKEYSLVDGDGMSLLVKPNGSKYWRFRFRFGGKQHLMAFGVYPEISLANARKKREEARKLVAAGID
PREHKRALKEEQAKEIITFEKVAREWLATNQKWSEDHANRVKKSLEDNIFPAIGTCNIAELGTRDLLAPIKAVEVSGRLE
VASRLQQRTTAIMRYAVQSGLIDYNPAQEMAGAVASGNRQHRPALELKRIPELLEKIDGYTGRPLTRWATELTLLIFIRS
SELRFARWSEIDFETSMWTIPPEREPIPGVKHSQRGSKMRTPHLVPLSKQALAILKQIKQFCGEHELIFIGDHDPRKPMS
ENTVNSALRVMGYDTKVEVCGHGFRTMACSSLIESGLWSKDAVERQMSHMERNSVRAAYIHKAEHLDERKLMLQWWANFL
DANREKSISPFDFAKINNPMLTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 1e-160 84
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 8e-145 68
int AAK00456.1 Int Not tested SHI-1 Protein 1e-135 68
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 8e-145 68
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 1e-142 67
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 3e-144 67
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 3e-144 67
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 2e-144 67
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 5e-144 67
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 3e-142 67
int AAK16198.1 Int Not tested PAI-I AL862 Protein 3e-144 67
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 3e-144 67
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 3e-143 66
int AAL51028.1 CP4-like integrase Not tested LEE Protein 5e-143 66
int-phe AAL60261.1 Int-phe Not tested LEE Protein 5e-143 66
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 3e-142 66
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 8e-143 66
int AAL51003.1 CP4-like integrase Not tested LEE Protein 5e-143 66
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 6e-143 66
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 5e-143 66
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 6e-143 66
int CAC81896.1 integrase Not tested LEE II Protein 1e-133 66
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 3e-132 63
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 3e-132 63
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 7e-82 58
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 1e-117 57
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 4e-95 57
int YP_002346908.1 integrase Not tested HPI Protein 7e-110 56
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 7e-110 56
int2 NP_993013.1 integrase Not tested HPI Protein 7e-110 56
int CAA08754.1 integrase Not tested HPI Protein 2e-110 56
int CAA21384.1 - Not tested HPI Protein 7e-110 56
int CAB59974.1 integrase Not tested HPI Protein 6e-111 55
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 1e-113 54
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 1e-113 54
unnamed AAD17660.1 unknown Not tested HPI Protein 2e-106 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 3e-103 52
int ACU09430.1 integrase Not tested LEE Protein 5e-81 43
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 7e-81 43
ECs4534 NP_312561.1 integrase Not tested LEE Protein 7e-81 43
int AAC31482.1 CP4-like integrase Not tested LEE Protein 5e-81 43
int AAD44730.1 Int Not tested SHI-2 Protein 5e-82 43
int CAC39282.1 integrase Not tested LPA Protein 2e-82 43
aec33 AAW51716.1 Int Not tested AGI-3 Protein 1e-82 43
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 1e-74 42
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 3e-80 42
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 2e-80 42
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 3e-80 42
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 6e-71 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_0566 YP_006496338.1 integrase VFG1536 Protein 6e-161 84
A225_0566 YP_006496338.1 integrase VFG0626 Protein 3e-145 68
A225_0566 YP_006496338.1 integrase VFG1693 Protein 1e-143 66
A225_0566 YP_006496338.1 integrase VFG0783 Protein 3e-81 43
A225_0566 YP_006496338.1 integrase VFG0598 Protein 1e-80 42