Gene Information

Name : A225_4890 (A225_4890)
Accession : YP_006500563.1
Strain : Klebsiella oxytoca E718
Genome accession: NC_018106
Putative virulence/resistance : Virulence
Product : DNA-binding heavy metal response regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5131414 - 5132094 bp
Length : 681 bp
Strand : +
Note : -

DNA sequence :

ATGCGCCTGTTGTTAGTCGAAGATGAAGAAAAAACGTCAACCTATCTCAACCGTGCGCTGGGTGAGTCCGGATTTACGGT
AGATGTCTCTGCAGACGGAGCTGAAGGTCTTCATTACGCGCTGGAGTTCGACTACGACGCGATAATACTGGATGTGATGC
TGCCGGGGATGGATGGCTACGGGGTGCTCGAGGGTGTGCGAGCAGCCAAACAGACGCCGGTGCTGATGCTCTCGGCACGG
GGTTCGGTCGATGAACGCGTTAAAGGGCTTCGCCTTGGCGCGGATGATTATCTCCCTAAGCCCTTTTCCCTTATTGAGCT
GGTGGCGCGTATTCAGGCACTGGTGCGCCGCCGCGCTACGGATGGCGCAGACATCACCCAGCTGCAAATTCACGATCTGC
ATCTCGACCTGCTGGCTCGTCGCGTATTTCGCGCCGGAACACGGCTGGAGCTGACCGCGAAAGAGTTTTCCCTGTTGAGC
CTTTTGGCCCGGCATCAGGGAGAGATTCTGTCAAAAATGATGATTGCGGAGCAGATATGGGACATGAATTTCGACAGCGA
TGCCAACGTGGTTGAAGTGGCCATTAAACGACTTCGGGCCAAAGTGGATGCGCCGTTCGATATCAAGCTGTTACATACCG
TTCGTGGCATGGGGTATGTCCTCGAAGTCCGGTCCGAATAA

Protein sequence :

MRLLLVEDEEKTSTYLNRALGESGFTVDVSADGAEGLHYALEFDYDAIILDVMLPGMDGYGVLEGVRAAKQTPVLMLSAR
GSVDERVKGLRLGADDYLPKPFSLIELVARIQALVRRRATDGADITQLQIHDLHLDLLARRVFRAGTRLELTAKEFSLLS
LLARHQGEILSKMMIAEQIWDMNFDSDANVVEVAIKRLRAKVDAPFDIKLLHTVRGMGYVLEVRSE

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
copR	NP_460069.2	transcriptional regulatory protein YedW	Not tested	SPI-5	Protein	3e-50	52
copR	AAC33719.1	regulatory protein CopR	Not tested	SPI-5	Protein	6e-49	51

• Homologs from CARD and BacMet (resistance genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	BAC0083	Protein	7e-57	60
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	BAC0125	Protein	1e-59	59
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	BAC0197	Protein	1e-55	58
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	BAC0638	Protein	3e-52	57
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	BAC0111	Protein	2e-55	54
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	BAC0347	Protein	1e-47	49
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	BAC0308	Protein	2e-51	48

• Homologs from VFDB (virulence genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	VFG0596	Protein	1e-50	52
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	VFG1389	Protein	2e-36	47
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	VFG1390	Protein	1e-35	43
A225_4890	YP_006500563.1	DNA-binding heavy metal response regulator	VFG1386	Protein	8e-35	43