Gene Information

Name : A225_4884 (A225_4884)
Accession : YP_006500557.1
Strain : Klebsiella oxytoca E718
Genome accession: NC_018106
Putative virulence/resistance : Resistance
Product : Arsenic efflux pump protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5124429 - 5125721 bp
Length : 1293 bp
Strand : -
Note : -

DNA sequence :
ATGCTACTGGCAGGTGCTATTTTTGTCCTGACCATTGTTCTGGTTATCTGGCAGCCGAAGGGATTAGGCATCGGCTGGAG
CGCGACGCTGGGCGCGGTACTGGCTTTAATTGCTGGCGTCGTACATGTAGGTGATATTCCGGTGGTGTGGAATATCGTCT
GGAACGCGACGGCGACCTTTATTGCGGTGATTATTATCAGCCTGCTGCTCGATGAGTCCGGCTTTTTTGAATGGGCTGCG
CTGCACGTATCTCGTTGGGGAAACGGTCGTGGCCGTTTGCTGTTTACGTATATCATTCTGCTCGGCGCAGCGGTGGCGGC
GTTGTTTGCCAACGATGGTGCGGCATTAATATTGACGCCCATCGTGATTGCCATGCTGCTGGCACTAGGATTCAGCAAGG
GTACGACGCTGGCCTTTGTGATGGCTGCCGGGTTTATTGCCGATACTGCCAGCCTGCCGCTTATTGTGTCGAATCTGGTG
AACATCGTCTCGGCGGATTTCTTTGGGCTGGGATTCACCGAATATGCGTCGGTAATGGTACCGGTCGATATTGCCGCCAT
TGGCGCCACGCTAGTGATGCTGCACCTGTTCTTTCGCAAAGATATCCCGCCGGCCTACGATCTGGCCCTGCTTAAATCAC
CGGCAAACGCAATTAAAGATCCGGCTACGTTCCGCACCGGCTGGATAGTATTGATTGTGCTGCTGGTAGGTTTTTTCGTC
CTCGAGCCGCCTGGCATTCCGGTCAGCGCGATTGCCGCGGTAGGGGCGGTAATACTGTTTACCGTGGCGAAACGAGGCCA
TGCCATTAACACCGGCAAAGTGTTACGCGGTGCGCCCTGGCAGATCGTGATTTTCTCGCTGGGAATGTATCTGGTGGTAT
ATGGTCTGCGCAACGCCGGGCTAACCGAATACCTTTCAGGGGTGCTGAACGTGCTGGCGGATAAAGGACTCTGGGCCGCG
ACGCTGGGTACTGGCTTCCTGATGGCTTTCCTGTCTTCCATCATGAACAACATGCCTTCCGTGCTGGTTGGTGCGCTCTC
TATTGATGGAAGCACCGCAACCGGCGTTATTAAAGAGGCGATGATCTACGCTAACGTAATTGGCTGCGATCTGGGCCCGA
AAATTACACCAATCGGTAGCCTGGCAACGCTGCTCTGGCTGCACGTACTTTCACAGAAGAATATGACCATCACCTGGGGC
TACTATTTCCGCACCGGGATCGTCATGACTCTGCCTGTGCTGTTTGTAACGCTGGCCGCGCTGGCGCTACGTCTCTCTTT
CACTTTGTCATGA

Protein sequence :
MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALIAGVVHVGDIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAA
LHVSRWGNGRGRLLFTYIILLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFGLGFTEYASVMVPVDIAAIGATLVMLHLFFRKDIPPAYDLALLKSPANAIKDPATFRTGWIVLIVLLVGFFV
LEPPGIPVSAIAAVGAVILFTVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADKGLWAA
TLGTGFLMAFLSSIMNNMPSVLVGALSIDGSTATGVIKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTITWG
YYFRTGIVMTLPVLFVTLAALALRLSFTLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 2e-174 94
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 2e-107 60
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 3e-105 59
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 4e-109 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_4884 YP_006500557.1 Arsenic efflux pump protein BAC0576 Protein 1e-178 97
A225_4884 YP_006500557.1 Arsenic efflux pump protein BAC0578 Protein 7e-179 97
A225_4884 YP_006500557.1 Arsenic efflux pump protein BAC0031 Protein 8e-175 93
A225_4884 YP_006500557.1 Arsenic efflux pump protein BAC0577 Protein 2e-168 90
A225_4884 YP_006500557.1 Arsenic efflux pump protein BAC0574 Protein 9e-108 59
A225_4884 YP_006500557.1 Arsenic efflux pump protein BAC0575 Protein 2e-110 59