Gene Information

Name : A225_4608 (A225_4608)
Accession : YP_006500284.1
Strain : Klebsiella oxytoca E718
Genome accession: NC_018106
Putative virulence/resistance : Virulence
Product : manganese ABC transporter
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4842686 - 4843534 bp
Length : 849 bp
Strand : +
Note : inner membrane permease protein SitC

DNA sequence : 
ATGAGCTGGCTACTGGAGCCGTTTGGTTATCACTATATGCTGAACGCGATGTGGGTCTCGGCGCTGGTGGGCGGGGTGTG
CGCGTTTCTCTCCTGCTACCTGATGCTTAAAGGCTGGTCGCTGATTGGCGACGCCCTCTCCCACTCCATCGTGCCCGGCG
TGGCGGGCGCTTATATGCTCGGTCTGCCCTTCGCGCTGGGGGCGTTTCTTTCCGGCGGCCTGGCGGCGGGCAGCATGCTG
TTTCTTAACCAGCGTTCGAAGCTGAAGGAAGACGCGATTATCGGCCTGATCTTCTCCTCTTTTTTCGGTATTGGCCTGTT
TATGGTGTCGCTGAACCCCACTTCGGTGAATATCCAGACCATTATTCTCGGCAATATTCTGGCCATCGCCCCGGAGGATA
TTATCCAGCTGGCGGCGATTGGCTCTATTTCGATGGCGATTCTGCTGCTGAAGTGGAAAGACCTGATGGTGACCTTTTTC
GATGAGAACCACGCTCGTTCCATTGGCCTGAATACCACCGCGCTGAAGCTGCTGTTCTTTACCCTGCTGGCGGCCTGTAC
CGTGGCGGCGCTGCAGACCGTCGGCGCGTTTCTGGTGATTTGCCTGGTGGTGACGCCCGGGGCCACCGCCTGGCTGTTGA
CCGACCGCTTCCCGCGCCTGCTGGCGATTGCCGTCGCGATTGGCAGCCTGACCAGCTTTTTCGGCGCGTGGCTGAGCTAC
TATCTGGACGGGGCGACCGGCGGGATTATCGTCGTCGCCCAGACGCTGCTGTTTTTAGCCGCTTTTGTTTTCGCGCCGAA
GCACGGCCTGCTCGCCAGCCGTCGCCGCGCCAGGGAGGCCTCATGCTGA

Protein sequence : 
MSWLLEPFGYHYMLNAMWVSALVGGVCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFALGAFLSGGLAAGSML
FLNQRSKLKEDAIIGLIFSSFFGIGLFMVSLNPTSVNIQTIILGNILAIAPEDIIQLAAIGSISMAILLLKWKDLMVTFF
DENHARSIGLNTTALKLLFFTLLAACTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLAIAVAIGSLTSFFGAWLSY
YLDGATGGIIVVAQTLLFLAAFVFAPKHGLLASRRRAREASC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 6e-74 88
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 6e-74 88
sitC NP_461784.1 permease Virulence SPI-1 Protein 6e-74 88
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 4e-74 88
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 6e-74 88
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 2e-30 42
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 5e-30 42
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 5e-30 42
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 4e-30 42
sitD NP_461785.1 permease Virulence SPI-1 Protein 2e-30 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_4608 YP_006500284.1 manganese ABC transporter BAC0351 Protein 3e-74 88
A225_4608 YP_006500284.1 manganese ABC transporter BAC0441 Protein 1e-54 70
A225_4608 YP_006500284.1 manganese ABC transporter BAC0352 Protein 1e-30 42
A225_4608 YP_006500284.1 manganese ABC transporter BAC0442 Protein 2e-25 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_4608 YP_006500284.1 manganese ABC transporter VFG0527 Protein 2e-74 88
A225_4608 YP_006500284.1 manganese ABC transporter VFG0528 Protein 1e-30 42