Gene Information

Name : A225_4518 (A225_4518)
Accession : YP_006500199.1
Strain : Klebsiella oxytoca E718
Genome accession: NC_018106
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4757488 - 4759008 bp
Length : 1521 bp
Strand : -
Note : -

DNA sequence :
ATGCGTTATGCTCATCCTGGCACACCGGGCGCTTTGGTTTCACTGAAGTCAGCCTACGGTAACTTTATTGACGGTAAATT
TGTTGAACCCATCGGTGGAGAATTCTTTATGAATACCTCCCCGGTCGACGGTAGCAACATCGGGCAGTTTCCGCGTTCTG
ATGCCAAAGATATCGACTTCGCCCTTGATGCGGCGCACCGGGCCGCCGACGCCTGGGGCAAAACGTCGGCTCAGCACCGC
GCTAATCTGCTGCTGCAGGTTGCCGACCGTATTGAGGCCAATCTGGAATATCTGGCGGTAGCGGAGAGCTGGGATAACGG
TAAGCCGATCCGCGAAACCCTCAACGCCGACCTGCCGCTGGCGGTCGATCACTTCCGCTATTTCGCCGGCTGCCTGCGCG
CGCAGGAGGGAAGCACGGCGGAGATTGATGAAACGACGGTGGCTTATCACTTCCATGAGCCTCTCGGCGTGGTCGGACAA
ATTATTCCGTGGAACTTCCCGCTGCTGATGGCCGCCTGGAAGCTCGCTCCGGCGCTGGCTGCGGGCAACTGCGTGGTGCT
GAAACCGGCAGAGCAGACGCCTCTCAGCATTACATTGCTGCTGGAGATTATTGGCGATCTGTTCCCGGCGGGCGTCCTTA
ACGTGGTTCAGGGATTTGGCAAAGAGGCGGGCGAAGCGCTGGCAACCAGTAAACGCATCGCCAAAATCGCCTTTACCGGC
TCAACGCCGGTAGGCCGCCATATCATGGCCTGCGCGGCGGAAAACATTATCCCCTGCACCGTTGAGCTGGGCGGTAAATC
GCCGAATATCTACTTTGCCGACGTGATGGAAGGCGAAGAAGAGTATATCGAGAAGGCGGTTGAAGGCCTGGTTCTGGGCT
TCTTTAATCAGGGTGAGGTCTGCACCTGCCCGTCCCGCGCGCTGATTCAGGAGTCTATTTACGAGCCCTTTATGGCGCGG
GTCATGGAGAAGGTGGCGCAAATTCGCCGCGGCGACCCCTTTGATACCGATACGATGATCGGCGCGCAGGCGTCGCGTCA
GCAGTTCGATAAGATCCTTTCCTATATTAAGATCGCTCGCGATGAAGGCGGAAAGATCCTGACCGGCGGCGAACGCGCCA
GCATCTCTGCCGAACTGGATAACGGTTTCTATATTCAGCCGACGCTGATTCAGGGCCGCAACGATATGCGCAGCTTCCAG
GAGGAGATCTTTGGCCCGGTTATCGGCGTCACCACCTTTAAAGATGAAGCCGAGGCGCTGGCTATTGCAAACCAAACCCA
GTTTGGCCTTGGGGCCGGGGTGTGGACGCGGGATACCAACCTGGCTTATCGCATGGGGCGCGGCATTAAGGCCGGTCGGG
TGTGGACCAACTGCTATCACATCTACCCTGCGCACGCCGCGTTCGGCGGCTACAAACAGTCCGGCGTAGGGCGCGAAACC
CATAAGATGGCGCTCAATGCCTATCAGCAGACGAAGAACCTGCTGGTGAGCTACGGTACCGCGCCGCTGGGCCTGTTCTG
A

Protein sequence :
MRYAHPGTPGALVSLKSAYGNFIDGKFVEPIGGEFFMNTSPVDGSNIGQFPRSDAKDIDFALDAAHRAADAWGKTSAQHR
ANLLLQVADRIEANLEYLAVAESWDNGKPIRETLNADLPLAVDHFRYFAGCLRAQEGSTAEIDETTVAYHFHEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLSITLLLEIIGDLFPAGVLNVVQGFGKEAGEALATSKRIAKIAFTG
STPVGRHIMACAAENIIPCTVELGGKSPNIYFADVMEGEEEYIEKAVEGLVLGFFNQGEVCTCPSRALIQESIYEPFMAR
VMEKVAQIRRGDPFDTDTMIGAQASRQQFDKILSYIKIARDEGGKILTGGERASISAELDNGFYIQPTLIQGRNDMRSFQ
EEIFGPVIGVTTFKDEAEALAIANQTQFGLGAGVWTRDTNLAYRMGRGIKAGRVWTNCYHIYPAHAAFGGYKQSGVGRET
HKMALNAYQQTKNLLVSYGTAPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-149 65
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-154 64
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-154 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-154 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-153 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_4518 YP_006500199.1 aldehyde dehydrogenase VFG0082 Protein 1e-149 65