Gene Information

Name : A225_4443 (A225_4443)
Accession : YP_006500124.1
Strain : Klebsiella oxytoca E718
Genome accession: NC_018106
Putative virulence/resistance : Virulence
Product : clpB protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4685172 - 4687643 bp
Length : 2472 bp
Strand : -
Note : -

DNA sequence :
ATGAGCGCCTTGCTGAATCAGGAAGGGGGATCGATACGTCCTTTATTAACTTCGGCGGGCATCAATGCCGGAGAGTTGCG
CACCAATATTGAACAGGCGTTGAGCCGATTGCCGCAGGTGGAAGGTACCGGCGGCGATGTTCAACCGTCCCAGGATTTAG
TGCGTATTCTGAACCTTTGCGACAAGCTGGCGCAAAAGAGAAAGGACAACTTTATTTCGTCAGAGCTGTTCGTTCTGGCA
GCGCTTGAATCACGCGGCACGCTGACCGACCTTTTAAAATCCGCCGGGGCCACAACCGCCAACGTGAGTCAGGCGATCGA
ACAAATGCGCGGAGGTGAAAGCGTGAACGATCAGGGAGCCGAAGACCAACGTCAGGCCTTGAAAAAATTTACCGTCGATC
TGACCGAACGTGCTGAGCAGGGCAAGCTTGACCCGGTGATTGGCCGCGATGAAGAAATTCGTCGTACGATTCAGGTTCTG
CAGCGCCGTACCAAAAACAACCCGGTGCTGATTGGTGAACCCGGTGTAGGTAAAACGGCCATTGTTGAAGGGCTGGCGCA
GCGGATCGTCAACGGTGAAGTGCCGGAAGGGCTGAAGGGGCGCCGGGTGCTGGCGCTCGATATGGGCGCGCTGGTGGCGG
GTGCCAAATACCGCGGTGAGTTTGAAGAGCGCTTAAAAGGCGTTCTGAATGACCTCGCCAAGCAGGAAGGCAACGTCATC
CTGTTTATCGATGAGCTGCACACCATGGTGGGTGCGGGTAAAGCGGATGGCGCAATGGACGCCGGTAACATGCTGAAACC
GGCGCTGGCGCGCGGTGAGCTGCACTGCGTGGGCGCTACGACGCTGGATGAATATCGTCAGTACATTGAGAAAGACGCCG
CGCTGGAACGTCGTTTCCAGAAAGTATTCGTGGCGGAGCCGACCGTTGAAGATACCATTGCGATTTTGCGTGGTCTGAAA
GAACGTTATGAACTGCACCACCACGTGCAGATCACCGACCCGGCGATTGTTGCGGCAGCCACGCTGTCTCATCGCTATAT
CGCCGACCGACAGCTGCCGGATAAAGCTATCGACCTGATCGATGAAGCTGCATCCAGCATTCGGATGCAGATTGACTCAA
AACCGGAAGAGCTGGACAGACTCGACCGTCGCATCATTCAGCTCAAGCTGGAACAGCAGGCGCTGAAGAAAGAGTCTGAT
GAAGCCAGCATTAAGCGGCTGGATATGCTGAATGAGGAACTGGCCGATAAAGAACGTCAATATTCAGTCTTAGAAGAAGA
GTGGAAGGCTGAAAAAGCATCGCTCTCCGGAACCCAGACGATTAAGGCTGAGCTGGAACAGGCGAAAATCGCTATTGAGC
AGGCGCGTCGCGTCGGCGATCTGGCGCGGATGTCCGAGCTGCAGTATGGCAAAATCCCGGAGCTGGAAAAACAGCTGGCG
GCGGCAACGCAATCCGAAGGCAAGACGATGCGTCTGTTGCGTAATAAAGTTACGGATGCGGAAATCGCGGAAGTGCTGGC
TCGCTGGACGGGTATCCCGGTGGCCAGAATGCTGGAAGGCGAGCGTGAGAAGCTGCTGCGTATGGAGCAGGAGCTGCATA
GTCGCGTCATTGGTCAGAACGAAGCGGTCGAAGCGGTATCGAATGCGATCCGCCGTAGCCGTGCCGGATTATCCGATCCT
AATCGTCCAATTGGCTCGTTCCTGTTCCTGGGCCCTACCGGTGTAGGTAAAACAGAACTCTGTAAAGCGCTGGCCAACTT
TATGTTTGATAGCGACGATGCGATGGTACGTATCGACATGTCAGAGTTTATGGAGAAACACTCCGTTTCACGTCTGGTTG
GGGCGCCTCCGGGATACGTCGGTTATGAAGAAGGCGGCTATCTCACTGAAGCGGTCCGCCGTCGTCCTTATTCCGTCATC
CTGCTGGATGAAGTGGAAAAAGCGCATCCGGATGTCTTTAACATTCTGCTGCAGGTACTGGACGATGGACGTTTGACTGA
CGGGCAGGGGAGAACGGTCGACTTCCGCAATACGGTCGTCATCATGACCTCTAACCTCGGTTCGGATCTCATTCAGGAAC
GTTTTGGTGCCCTGGACTATAGCCACATGAAAGAGCTGGTTCTGGGCGTGGTTAGCCAAAGCTTCCGGCCGGAGTTTATC
AACCGTATTGATGAAGTGGTGGTATTCCACCCGTTAGGTGAAAAACACATTGCTTCTATTGCGCAGATTCAGCTGCAGCG
GTTGTATAAACGACTTGAGGAACGCGGCTATGAAGTTCACCTCTCTGATGAGGCACTGAAGCTGCTGAGCGAAAACGGTT
ACGATCCGGTTTATGGCGCACGTCCTCTGAAACGTGCTATCCAGCAGCAGATCGAAAACCCGTTGGCGCAGCAGATTCTC
TCTGGTGAGCTAATACCGGGTAAAGAAGTGCAGCTGGTTGTGAAAAACGACCGGATAGTGGCAGTGCAGTAA

Protein sequence :
MSALLNQEGGSIRPLLTSAGINAGELRTNIEQALSRLPQVEGTGGDVQPSQDLVRILNLCDKLAQKRKDNFISSELFVLA
ALESRGTLTDLLKSAGATTANVSQAIEQMRGGESVNDQGAEDQRQALKKFTVDLTERAEQGKLDPVIGRDEEIRRTIQVL
QRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVI
LFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVAEPTVEDTIAILRGLK
ERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALKKESD
EASIKRLDMLNEELADKERQYSVLEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPELEKQLA
AATQSEGKTMRLLRNKVTDAEIAEVLARWTGIPVARMLEGEREKLLRMEQELHSRVIGQNEAVEAVSNAIRRSRAGLSDP
NRPIGSFLFLGPTGVGKTELCKALANFMFDSDDAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVI
LLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGALDYSHMKELVLGVVSQSFRPEFI
NRIDEVVVFHPLGEKHIASIAQIQLQRLYKRLEERGYEVHLSDEALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQIL
SGELIPGKEVQLVVKNDRIVAVQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-154 46
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-102 43
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-97 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 8e-98 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_4443 YP_006500124.1 clpB protein VFG2076 Protein 5e-111 45