Gene Information

Name : A225_4163 (A225_4163)
Accession : YP_006499855.1
Strain : Klebsiella oxytoca E718
Genome accession: NC_018106
Putative virulence/resistance : Virulence
Product : type 1 fimbriae anchoring protein FimD
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4398170 - 4400719 bp
Length : 2550 bp
Strand : -
Note : -

DNA sequence :
ATGAAAAATAATCATAATAAATGGCGGCTTAACCGGATAGCCGGCGCTCTGGCCGTTGCGCTGCTACCGCTGTGTGAAGA
TGTCCTGGCGCGGGAGGTTTTTAACCCGGCCCTGTTGGAAATGGACGGCCCTCATACGGGCGTCAGGGATTTATCCGCTT
ACGAGCAGGCTGGCGGACAGCTGCCGGGGACCTACCGGGTAGATATTTATCTTAATAACGTTTTTATGGACACCCGCGAT
GTGGTTTTTCAGCAGAGCAAAGGACCAGGAATAACGGAATTACAGCCTTGCCTGACGGTAGACGATCTGGCCGAATGGGG
CGTGCGCGTCTCCCAATTTCCAGAGCTGGGCCGCAGAACGCCCGGCTGCGCGGATATCAGCGTGATACCGCAGGCAAAAT
CCGATTTTCGCTTCAGCCAGCAGCGCCTGCTATTGAGCTTCCCGCAGGCGGCGGTAGCCAGCGCCGCCCGCGGCTGGGTG
GATCCGAAACAGTGGGATGAGGGGGTGCCGGCGATCCTGCTGAATTACTCCTTTAGCGGGGCAAATAACTGGTCACGTCA
GAACGATGCGCCGGACAGCGATAACCAATACGTTAACCTGCGCCCCGGTATCAACGTCGGGCCGTGGCGTTTACGTAACT
ACACGACCTGGTCGCGCAGCAGCAGCGGGGGAGAGTCCAGTAATAGTTGGGACACGGTTTATACCTATGCGCAGCGCAAC
ATCAAATCGATACAGGGGGTGATGACGCTGGGCGATAGCAGCACGGACGCCGACGTTTTTGAGGGCGTTCCCTTCCGTGG
GGCGATGCTGGCTTCCGATGACGATATGCTGCCGGAAAGCCTGCGCGGCTACGCGCCCGTCGTTCGCGGGATTGCGCGCA
CTAATGCTCAGGTCATTATTCGCCAGAACGGCTATGAGATTTACCAGACCTACGTCGCGCCTGGCGCTTTTGAAATTACC
GATATGTACCCGACCGGCGGCTCGGGTGATTTAGCCGTCACCATCAAAGAGGCGGACGGCAGCGAGCAGAACCTGATCGT
ACCTTACGCTTCTCTCCCTGTCCTGCAGCGCGAAGGGCGTCTGAAATATAGCGTGACCTCCGGCGTGTATCGCGCCTATG
ACAACAGCATTGACGAAACGCCCCTCACGCAGGCGACGGCAATTTACGGCTTGCCCTGGGGGTTAACCCTGTACGGCGGC
GGCCAGTTTAGCAGTAAATATCAGTCGGTGGCGCTGGGAATGGGGAAAAACCTCGGTGAACTGGGCGCCGTATCGACCGA
TATCATCCAGGCCTGGTCGACCCGACAGGATAAAGATAAAGAGAGCGGGCAGTCGGTACGTCTCCGTTACAGCAAAGATC
TCCCGGGTCTGGGAACTAACGTAAGCCTGGCAGGCTATCGCTATGCGACCAGCGGTTACTGGGATATGCAGGAAGTGCTG
GATACCTATCGGGATGACAACTACACGCCTTCTATTGAACGGCGGCGCAACCGCGGGGAGGTAACGATCAGCCAAAGCCT
TGGCGAAGAAATGGGATCGCTGTCGCTGAGCTATATCCGCGAGGACTACTGGAATACCAGCCGCACCATGGAGTCAGTGG
GCGTCGGATACAACAACAGCTGGCGCGGCATCAGCTATAGCATGAACTACAGCTATAACCGCAATACTACCGACCAGAAC
ACCGGTAAGCGTAATGACGAAGATCACCTCTTTGCACTGAGCATCAGCGTGCCTTTGGGGGAATGGCTACCGAAGCCGGT
TTATGCCAACTACTCCCTGAACAGCAGCAAAAATGGCTCCACCAGCAACAATCTGGGCCTCTCCGGCACCTTGCTGGAGC
GTAATAACCTGAGCTGGAGCGTGCAGGAAGGCTACACCAGCCAGGGAAGAGGGGAGAGCGGCAGCGTCAATGCGGACTGG
CGTGCAACCTATGCTGAACTTACCGGCGGCTACAGCCATGATAAATACAGCCATCGGCTGAACTACGCCCTGCGCGGCGG
AGCGCTGGTACATGAAAACGGCCTGACGCTGGGCCAGCCTTTCGGCGAAACCGTCGCTCTCATCAAGGCGCCCGGCGCCG
CCGGCGTCGGCGTGAATAGCCAGACAGGGGTCAGAACCGACTGGCGAGGCTATACCGTAGTGCCTTACGCCTCGCCGTAT
CGTAAGAATATCCTGACGCTCGATACCACGACGATGCCGGACGATGTCGACCTTGAGTTGGCGACGCAGACGGTCGTACC
AACCCGTGGGGCGGTGGTTCGCGCAAATTATGCCACCAGCGTGGGTAACCGGGTACTGATGACGGTACGCCAGGAGAACG
GGCAACCCCTGCCTTTCGGAGCCATGGTCAGCGTCCCCGGGGCGGCATCCTCTGAGCAGGCGTTTATCGTTGGCGATGGC
GGGCAGGTCTACCTGACCGGACTGGAATCTAACGGCGTACTCAACGTGAAGTGGGGCTCCGGGGCGCAAGAACGCTGCCA
GATCCACTATGCGCTGCCGTCAGCAAAAGAACTTACCGGCATTATTGTGGCCCAGGCGCAATGCCGATAA

Protein sequence :
MKNNHNKWRLNRIAGALAVALLPLCEDVLAREVFNPALLEMDGPHTGVRDLSAYEQAGGQLPGTYRVDIYLNNVFMDTRD
VVFQQSKGPGITELQPCLTVDDLAEWGVRVSQFPELGRRTPGCADISVIPQAKSDFRFSQQRLLLSFPQAAVASAARGWV
DPKQWDEGVPAILLNYSFSGANNWSRQNDAPDSDNQYVNLRPGINVGPWRLRNYTTWSRSSSGGESSNSWDTVYTYAQRN
IKSIQGVMTLGDSSTDADVFEGVPFRGAMLASDDDMLPESLRGYAPVVRGIARTNAQVIIRQNGYEIYQTYVAPGAFEIT
DMYPTGGSGDLAVTIKEADGSEQNLIVPYASLPVLQREGRLKYSVTSGVYRAYDNSIDETPLTQATAIYGLPWGLTLYGG
GQFSSKYQSVALGMGKNLGELGAVSTDIIQAWSTRQDKDKESGQSVRLRYSKDLPGLGTNVSLAGYRYATSGYWDMQEVL
DTYRDDNYTPSIERRRNRGEVTISQSLGEEMGSLSLSYIREDYWNTSRTMESVGVGYNNSWRGISYSMNYSYNRNTTDQN
TGKRNDEDHLFALSISVPLGEWLPKPVYANYSLNSSKNGSTSNNLGLSGTLLERNNLSWSVQEGYTSQGRGESGSVNADW
RATYAELTGGYSHDKYSHRLNYALRGGALVHENGLTLGQPFGETVALIKAPGAAGVGVNSQTGVRTDWRGYTVVPYASPY
RKNILTLDTTTMPDDVDLELATQTVVPTRGAVVRANYATSVGNRVLMTVRQENGQPLPFGAMVSVPGAASSEQAFIVGDG
GQVYLTGLESNGVLNVKWGSGAQERCQIHYALPSAKELTGIIVAQAQCR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 4e-147 43
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 2e-147 41
safC NP_454907.1 outer-membrane fimbrial usher protein Not tested SPI-6 Protein 4e-131 41
afaC AAD44022.2 AfaC Virulence PAI-I AL862 Protein 2e-139 41
afaC ADD91743.1 putative AfaC-VIII usher protein Not tested PAI-I AL862 Protein 2e-141 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_4163 YP_006499855.1 type 1 fimbriae anchoring protein FimD VFG0454 Protein 3e-158 43
A225_4163 YP_006499855.1 type 1 fimbriae anchoring protein FimD VFG1645 Protein 2e-147 43
A225_4163 YP_006499855.1 type 1 fimbriae anchoring protein FimD VFG0876 Protein 1e-151 43
A225_4163 YP_006499855.1 type 1 fimbriae anchoring protein FimD VFG0912 Protein 1e-147 43
A225_4163 YP_006499855.1 type 1 fimbriae anchoring protein FimD VFG0944 Protein 6e-142 42
A225_4163 YP_006499855.1 type 1 fimbriae anchoring protein FimD VFG0446 Protein 1e-141 42