Gene Information

Name : A225_2996 (A225_2996)
Accession : YP_006498707.1
Strain : Klebsiella oxytoca E718
Genome accession: NC_018106
Putative virulence/resistance : Virulence
Product : iron aquisition 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3182391 - 3183968 bp
Length : 1578 bp
Strand : +
Note : -

DNA sequence : 
ATGCATTCTTCTTTTGATTCTCTGATAAAACAGTATCCCTTCCCCATTGCTGAACAGCTGCGCCACTGGGCAGCTCGCTA
TCCCTCGCGAACTGCTGTCGTTGATGCCAAAGGCTCGCTGACCTACAGCGCGCTCGATCTTCGGGTCGATGAGCTTGCTG
CAGGGTTATACTCGCTGGGTTTGCGTCCGGGAGAACATGTGCTTATCCAGCTCCCCAACGGCAACGCATTTGTGATCCTG
CTGTTCGCGCTGTTAAGACTGGGCGTTATCCCTGTTCTGGCGATGCCCTCGCAGCGGGCGCTGGATATTGACGCGCTGAT
CGCGCTGGCGCAACCGGCCGCTTATGTGATTCATGGAGAAAGCCACGCGGACCTGGCCCGCCAGATGGCGCGCAAACACG
CCTGCCTGCGGCAAGTTCTGGTCGCAGGTGAGACCGAAGGCGACGATTTTACGCCGCTCTTCTCGCTCCGCGGCGAACGG
CAGGCGTGGCCGCAGCCCGATGCTGCCGGCACCGCGCTGCTGCTGCTCTCAGGCGGCACCACCGGGACGCCAAAGCTTAT
CCCGCGACGGCACGCTGACTATAGCTATAACTTCAGCGCCTCCGCCGAACTGTGCGGCCTTAAGCCACAGAGCGTGTATC
TCGCCGTCCTCCCCGTGGCGCATAACTTTCCGCTGGCCTGCCCCGGTATTCTGGGAACCCTTGCCTGCGGCGGAAAAGTG
GTATTGACCGACAGCGCCAGCTGCGATGAGGTGATGCCTTTAATCGCTGAACAAGGCGTGACCCACGTCGCCCTGGTACC
GGCGCTGGCGCAGCTCTGGGTGCAGGCCAGAGAGTGGGAAGACAGCGATCTCTCTTCGCTACGCGTCATTCAGGTGGGCG
GCGCCCGGCTTGACCCAACGCTTGCTGAGCAGGTTATCTCGACGTTTGATTGTCCCCTGCAACAGGTATTCGGTATGGCG
GAAGGCCTGCTCTGCTTTACCCGGTTGGACGATCCTCTGGCCACCGTTCTCCACAGCCAGGGGCGCCCTATGTCTCCCCT
GGATGAAATTCACGTCGTTGACGAAGAGGAGAACGACGTTGCGCCCGGCGAAACGGGACAGTTATTAACGCGCGGTCCTT
ATACTATTACGGGCTATTATCGCGCTCCCGAGCACAATGCGCGGGCCTTTACCGCGCAGGGATTTTACCGTACGGGCGAC
AATGTCAGGCTCGATGAGGCGGGAAATCTGTACGTTGAGGGGCGTATAAAAGAGCAGATCAACCGCGCCGGAGAGAAAAT
AGCCGCTGCGGAAGTGGAATCGGTGCTGATGCGTCTGGAAGACGTAAAGGATTGCGCCGTGGTCGCCGCGCCGGACACGC
TGCTTGGCGAGCGGATATGCGCGTTTATCATCGCGCAACGCACTCCCTCTGACTATCAACAGCTGCGTCAAAAGCTGGTC
CGAATGGGAATCAGCGCGTGGAAGATTCCCGATCAAATTGAGTTTCTGACCCACTGGCCGCTCACCGCCGTCGGCAAGGT
AGATAAAAAGCGCCTGACGGCGCTCGCCATTGAGCGTTATCGCCATTCAGCCCAATAA

Protein sequence : 
MHSSFDSLIKQYPFPIAEQLRHWAARYPSRTAVVDAKGSLTYSALDLRVDELAAGLYSLGLRPGEHVLIQLPNGNAFVIL
LFALLRLGVIPVLAMPSQRALDIDALIALAQPAAYVIHGESHADLARQMARKHACLRQVLVAGETEGDDFTPLFSLRGER
QAWPQPDAAGTALLLLSGGTTGTPKLIPRRHADYSYNFSASAELCGLKPQSVYLAVLPVAHNFPLACPGILGTLACGGKV
VLTDSASCDEVMPLIAEQGVTHVALVPALAQLWVQAREWEDSDLSSLRVIQVGGARLDPTLAEQVISTFDCPLQQVFGMA
EGLLCFTRLDDPLATVLHSQGRPMSPLDEIHVVDEEENDVAPGETGQLLTRGPYTITGYYRAPEHNARAFTAQGFYRTGD
NVRLDEAGNLYVEGRIKEQINRAGEKIAAAEVESVLMRLEDVKDCAVVAAPDTLLGERICAFIIAQRTPSDYQQLRQKLV
RMGISAWKIPDQIEFLTHWPLTAVGKVDKKRLTALAIERYRHSAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 0.0 89
ybtE CAA21394.1 - Virulence HPI Protein 0.0 89
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 0.0 89
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 0.0 89
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 0.0 89
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 0.0 89
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 0.0 88
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 0.0 88
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 0.0 88
irp2E YP_005134497.1 siderophore biosynthetic protein Virulence Not named Protein 5e-75 42
irp2E YP_005163485.1 siderophore biosynthetic protein Virulence Not named Protein 4e-75 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_2996 YP_006498707.1 iron aquisition 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-104 50
A225_2996 YP_006498707.1 iron aquisition 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 1e-90 44
A225_2996 YP_006498707.1 iron aquisition 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 6e-80 43