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Name : A225_2992 (A225_2992) Accession : YP_006498703.1 Strain : Klebsiella oxytoca E718 Genome accession: NC_018106 Putative virulence/resistance : Virulence Product : iron aquisition yersiniabactin synthesis enzyme (Irp2) Function : - COG functional category : - COG ID : - EC number : - Position : 3164832 - 3170930 bp Length : 6099 bp Strand : + Note : - DNA sequence : ATGATTTCTGGCGCCCCCTCTCAGGACCCGCTGTTATCGGACAACGGCGAAGCGGCCGATTATCAACAATTACGCGAACT GTTATTACAGGAACTGAATGTAGCGCCGCAGCAGCTACAGGAAGAGAGCAATCTGATCCAGGCGGGCCTGGACTCCATAA GATTAATGAGATGGTTACACTGGTTTCGTAAAAAGGGCTACCGCCTCACCCTTCGCGAGCTGTATGCCGCCCCCACGTTG GCAGCATGGCGCCAGCTGATGCGCAGCCGTTCGGGTGAAAAACCGGATGATGCAAGCTCCCCGGCGGACGCGGCGTGGCC AGTCATGAGCGAGGGTACCCCCTTCCCGCTGACGCCGGTACAGCATGCCTATCTGACGGGCCGAATGCCCGGACAGACGC TGGGCGGCGTCGGTTGCCATCTGTATCAGGAGTTTGCCGGCCATTATCTGACGGCGCCAAAGCTGGAGCAGGCCATCACG ATCTTACTGCAACGCCACCCGATGCTGCATATCGCCTTTCGCGCCGACGGGCAGCAGGTCTGGCTACCGCAGCCATACTG GAACGGCGTCACCGTTCATGATTTACGCCAGACCGACGAGGCAAGCCGCCAGGCCTATCTGGAAACATTGCGCCAGCGCC TGAGCCACCGTCTTTTACGCGTGGAAATGGGCGAAACCTTTGATTTCCAGTTGACGCTCTTGCCGGACAATCGCCACCGC CTCCATGTCAATATCGACCTGCTGATTATGGATGCTTCCAGCTTTACGCTGTTTTTCGATGAACTTAACGCCCTGCTGGC CGGAGAGTCGCTGCCGCCCGGCGACCCCCGCTATGATTTCCGCGCTTATCTGCTGCACCAGCAGAAGATCAAACAGCCGC TGCTCGACAAAGCGCGCGCGTACTGGCTGGCGAAAGCATCAATGCTGCCACCCGCGCCGGTTTTACCGCTAGCCTGCGAA CCCGCCACGCTGCGTGAAGTCCGTAATACCCGACGCCGCATGATTGTCCCGACAACACGCTGGAACGCCTTTAGCCAACG GGCCGGTGAGAATGGCGTAACGCCGACAATGGCGCTGGCGACCTGTTTTGCTGCCGTTCTGGGGCGCTGGGGCGGCCTGA CGCGGCTGCTGCTCAATATCACGTTATTTGACCGCCAGCCGCTGCACCCGGCGGTTGACGAAATGCTTGCCGACTTCACC AATATTCTTCTGCTGGATACCGCCTGCGATGGCGATACCGTCAGCAACCTGGCGCGTAAAAACCAGCTCACGTTTACTGA GGACTGGGAGCATCGCCACTGGTCCGGCGTCGAGCTCCTTCGTGAACTCAAACGCCAGCAAAGCCATCCCCACGGCGCCC CGGTGGTATTTACCAGCAATCTGGGGCGCTCCCTGTACAGCAGCCGCGCCGAGTCGCCGCTGGGCGAACCGGAATGGGGC ATCTCGCAGACGCCGCAGGTCTGGATAGATCATCTGGCGTTCGAGCATCGGGGCGAGGTCTGGCTACAATGGGATAGCAA TGACGCGTTGTTCCCTCCGGCGCTGGTCGAGACGTTGTTCAACGCCTACTGCCAGCTGATTAACCAACTCTGCGATGATG AAAGCGCCTGGAAGAAGTCGTTCGCGGACAGGATGCCCCAAAGCCAGCGGGAGATACGTCAACGGGTTAACGCAACCGAC GCCCCCGTTCCTCAGGGCTTGCTGCATGAAGGCATTTTCCGCATCGCCCTCCGGCAACCGCAGGCGCTGGCGGTAACGGA CGCGCATTATCGGTGGAATTATCGTGAGCTGACCGAGAACGCGCGCCGCTGCGCTGGCAGGTTAATCGCGTGCGGGGTTC AGCCCGGCGACAATGTCGCTATTACAATGTCGAAAGGCGCGGGGCAGCTGGTTGCGGTCCTCGCCGTGCTGCTGTCCGGG GCGGTGTACGTTCCGGTTTCGCTCGACCAGCCCGCCGCGCGGCGCGGGAAAATCTACGCTGACGCCAACGTCCGGCTGGT GCTCACCTGCCAGCACGACGCCAGCGCCTGGTCAGACGATATTCCCCACCTGACCTGGCAGCAGGCCATTGAGGCGGAGC CGCTAGCCGACCAGGCGGCGCGCGCGCCGACGCAGCCGGCCTACATTATCTATACCTCCGGGTCGACCGGCACGCCGAAA GGCGTGGTCATTTCTCACCGTGCAGCGCTGAATACCTGCTGCGATATCAATAGCCGTTACCAGGTGGGTCCCGGAGACAG AGTGCTGGCCCTCTCCGCCCTGCATTTTGATTTATCGGTTTACGACATTTTTGGCGTTCTGAGCGCCGGCGGCTCGCTGG TTATCGTTATGGAAAATCAACGGCGCGATCCCCGCGCATGGTGCGAATTGATCCAGCGTCATCAGGTTACGCTCTGGAAC AGCGTCCCGGCGCTGTTCGATATGCTGTTGACCTGGTGTGAAGGTTTCGCCGACGCCGCGCCGGAGAAACTGCGGGCGGT CATGCTTTCCGGCGACTGGATCGGCCTCGATCTTCCTGCCCGCTATCACGCCTTCCGCCCCCAGGGACAGTTTATCGCCA TGGGCGGCGCCACCGAGGCGTCTATCTGGTCTAACGCCTGTGAAATTAACCGGGTCCCCGACCACTGGCGCGCCATCCCT TATGGTTTTCCGCTGGCCAACCAACGTTACCGGGTGGTGGATGAACTGGGCCGGGACTGCCCGGACTGGGTTCCGGGCGA ATTGTGGATTGGCGGTATCGGGGTCGCGGAAGGCTACTTTAACGATCCTGTACGCAGCGAGCAGCAGTTTGTAACGCAAT CGAACGCGCGCTGGTATCGCACCGGCGATCTCGGGTGCTACTGGCCAGACGGTACGTTAGAGTTCCTCGGTCGTCGCGAT AAGCAGGTCAAAGTCGGGGGATATCGCATCGAGCTGGGTGAAATCGAAAGCGCGCTCAGCCAGCTGGCGGGAGTGAAACA GTCAACCGTTGTGGCGATCGGCGAAAAAGAAAAGACCCTGGCGGCCTGGGTTGTGCCTCAGGGTTCGGCTTTCTGTGTTA CCCATCATCGGGACCCGGCGCTGCCCCAGGCGTGGCGCGGGCTTGCCGGAACGCTGCCCTGCTGCGTCTGCCCCCCGGAA ATCTCCGCCGGCCAGGTCGCTGATTTTCTTCAGCATCGCCTGTTAAAACTGAAACCGGGTCAAACTCCTGGCGCCGATCC TCTTCCCCTGATGAATGCTCTCGCTATCCAGCCTCGCTGGCGGGCCGTGGTGGAACGCTGGTTAGCCTTTCTCGTGACCC AACAGCGGCTGCAGCCCGCCGCTGAGGGTTATCAGGTTTGTGCGGGGGAAGCGCCGGAGAATGACCCTCCTTCTTTCAGC GGGCATGACCTCACCTTAACGCAGATCCTTCGCGGCGCTCGCCACGAACTGTCATTACTGAACGATGCGCGGTGGTCGCC GGAAAGTCTGGCTTTCGACCATCCGGCCAGCGCCCTGTATATCGAGGAACTGGCGACAATCTGTCAACAGCTTTCCCGGC GTTTACAGCGCCCGGTACGCCTGCTAGAGGTGGGTGTCCGCACCGCCCGCGCCGCAGAGTGCCTGCTAACCCGGCTCAGC GCTGACGAGATTGAGTATGTCGGGCTTGAGCACAGCCAGGAGCTGCTGCTGAGCGCCCGACAGCGGCTTGCACCGTGGTC TGACGCCCGTCTGGCCCTCTGGAGTGCAGACACGCTGGCGGCGCATGCTCATTCGGCGGACATTATCTGGCTGAATAACG CCCTGCATCGTCTGCTGCCGGAAGAGCCCGGGCTCCTCGCGGCATTACAGCAGCTGGCCGTTCCAGGCGCGCTGCTCTAT GTGTTGGAGTTTCGTCAGTTAACGCCCTCCGCCCTGCTCAGCACGCTTCTGTTAACCGATGGTCAGCCCGAAGCCTTACT TCACAATAGCGCTGACTGGGGGGCGATATTTACCGCCGCCGCTTTCAACTGCCAGCACGGCGATGAAGTCGAGGGATTGC AGCGCTTCCTCGTACAATGCCCCGTTAGCCAGGTACGCCGCGATCCTCGTCAGCTGCAGTCCGCTCTCGCCGAACGTCTG CCGGGGTGGATGGTACCGAAACGGATCTTCTTACTTGACGCCTTACCGCTGACGGCGAACGGCAAAATTGACTATCAGAC GCTAAAACGCTGTCATACCCCGGAAGCTGAAAACCGGACTGAAGCGGATTTACCCCTGGGCGATATTGAGAAGCAGGTTG CCGTCATCTGGCAGCCGCTCTTGTCGATGGGCGCCGTCAGCAGAGAAACCGACTTCTTCCAGCATGGCGGTGATAGCCTG CTAGCCACCAGGCTGATCGGACAGCTCCACCAGGCGGGTTATGAAGCACGATTAAGCGACCTGTTTAATCACCCCCGGCT GGCTGATTTTGCCGCCACGCTGCGTAAAACCGACCTCCCTGTTGAACAACCCTTTGTCCACTCCCCTGAAGAACGCTACC GGCCTTTCGCGCTGACTGATGTGCAGCAGGCTTACCTGGTCGGGCGTCAGCCGGGCTTTGCCCTTGGCGGCGTAGGCTCA CACTTCTTTGTTGAATTTGAAATTGCCGATCTGGATATTCACCGGCTGGAGAAGGTCTGGAACCGGTTAATCGCCCGCCA CGATATGCTGCGCGCCGTGGTGCGGGATGGACAACAGCGGGTTCTCGAACAGACTCCCCCATGGGTGATACCCGCGCACA TCCTGCACAGCCCCGAAGAGGCGCTGCAGGTACGCGACAGACTGGCGCATCAGGTTCTCAACCCTGAAGTATGGCCGGTA TTCGATCTTCAGGTCGGGTTCGTCGACGGGATGCCCGCCCGCCTGTGGCTGTGTCTGGATAACCTGTTGCTTGACGGGTT GAGCATGCAGATCCTGTTGTCAGAGCTGGAACACGGCTATCGCTATCCGCAGCAGCTGCCGCCGCCGCTTCCCATTACCT TCAGGGATTATCTGCAGCAACCCGCGCTGCGGACGCCCAATCCCGACTCTCTGGCATGGTGGCAAACGCAGCTTGATGAT ATTCCTCCGGCACCTGCGTTACCGCTACGCTGCTTGCCTCAGGACGTTGAGACGCCGCGCTTCGCACGGCTCTATGGGGC AATGGACAGCGCGCGCTGGCGTCGCCTGAAACAGCGGGCGGCTGATGCTCATCTCACCCCGTCGGCCGTACTGTTATCCG TGTGGTCAACGGTTCTTGCTGCATGGAGCGCACAGCCCGATTTCACGCTTAACCTTACGCTTTTCGACAGACGACCTCTG CACCCGCAAATCAACCAGATCCTGGGCGACTTTACTTCGCTGATGCTGCTGAGTTGGCATCCCGGCGAGAGCTGGCTGCA AAGCGCGCGGTTATTACAGCAGCGACTAAGCGAGAGCCTCAACCACCGCGATGTGTCGGCAATCCGCGTGATGCGGCAAC TGGCGCGGCGGCAAAACGTACCGGCTGTCCCAATGCCCGTCGTCTTTACCAGCGCGCTGGGCTTTGAGCAGGATAACTTC CTTGCCCGGCGCAATCTGCTCAAACCGGTGTGGGGTATATCCCAGACGCCGCAGGTCTGGCTCGATCACCAGGTTTATGA ATCCGAAGGGGAACTGCGCTTTAACTGGGATTTTGTCGCCGCCCTGTTTCCTGACGGGCAGGTGGAGCGCCAGTTTGCAC AGTATTGCGCGTTGCTTAACCGAATGGCGGAGGATGACAGCAGCTGGCAGCTGCCGCTCGCCGACCTGGTTCCCCCGCTT AAGGTCACGGAGCGACGCGCCCGCCGGCTGCGCCCTGAGCGCGCTCAGCCGCGGATCGCGGCGGACAAGAGCAGCGTCAG CCTGATTTGCGACACCTTTCGCGAGGTGGTTGGCGAGCCAGTCGCACCCGCAGAGAACTTTTTTGAGGCGGGCGCCACGT CGCTGAATCTGGTGCAGCTGCACGTCTTGTTACAACGTCACGAATTCGCCACCCTGACGCTGCTTGACCTGTTCACTCAC CCTTCTCCTGTCGCGCTGGCCAATTATCTCGCCGGCGTAGCCCTGGAGGAGAAAACCAAACGCGTGCGGCCGGTTCGCCG TCGTCAGCGGCGCATTTGA Protein sequence : MISGAPSQDPLLSDNGEAADYQQLRELLLQELNVAPQQLQEESNLIQAGLDSIRLMRWLHWFRKKGYRLTLRELYAAPTL AAWRQLMRSRSGEKPDDASSPADAAWPVMSEGTPFPLTPVQHAYLTGRMPGQTLGGVGCHLYQEFAGHYLTAPKLEQAIT ILLQRHPMLHIAFRADGQQVWLPQPYWNGVTVHDLRQTDEASRQAYLETLRQRLSHRLLRVEMGETFDFQLTLLPDNRHR LHVNIDLLIMDASSFTLFFDELNALLAGESLPPGDPRYDFRAYLLHQQKIKQPLLDKARAYWLAKASMLPPAPVLPLACE PATLREVRNTRRRMIVPTTRWNAFSQRAGENGVTPTMALATCFAAVLGRWGGLTRLLLNITLFDRQPLHPAVDEMLADFT NILLLDTACDGDTVSNLARKNQLTFTEDWEHRHWSGVELLRELKRQQSHPHGAPVVFTSNLGRSLYSSRAESPLGEPEWG ISQTPQVWIDHLAFEHRGEVWLQWDSNDALFPPALVETLFNAYCQLINQLCDDESAWKKSFADRMPQSQREIRQRVNATD APVPQGLLHEGIFRIALRQPQALAVTDAHYRWNYRELTENARRCAGRLIACGVQPGDNVAITMSKGAGQLVAVLAVLLSG AVYVPVSLDQPAARRGKIYADANVRLVLTCQHDASAWSDDIPHLTWQQAIEAEPLADQAARAPTQPAYIIYTSGSTGTPK GVVISHRAALNTCCDINSRYQVGPGDRVLALSALHFDLSVYDIFGVLSAGGSLVIVMENQRRDPRAWCELIQRHQVTLWN SVPALFDMLLTWCEGFADAAPEKLRAVMLSGDWIGLDLPARYHAFRPQGQFIAMGGATEASIWSNACEINRVPDHWRAIP YGFPLANQRYRVVDELGRDCPDWVPGELWIGGIGVAEGYFNDPVRSEQQFVTQSNARWYRTGDLGCYWPDGTLEFLGRRD KQVKVGGYRIELGEIESALSQLAGVKQSTVVAIGEKEKTLAAWVVPQGSAFCVTHHRDPALPQAWRGLAGTLPCCVCPPE ISAGQVADFLQHRLLKLKPGQTPGADPLPLMNALAIQPRWRAVVERWLAFLVTQQRLQPAAEGYQVCAGEAPENDPPSFS GHDLTLTQILRGARHELSLLNDARWSPESLAFDHPASALYIEELATICQQLSRRLQRPVRLLEVGVRTARAAECLLTRLS ADEIEYVGLEHSQELLLSARQRLAPWSDARLALWSADTLAAHAHSADIIWLNNALHRLLPEEPGLLAALQQLAVPGALLY VLEFRQLTPSALLSTLLLTDGQPEALLHNSADWGAIFTAAAFNCQHGDEVEGLQRFLVQCPVSQVRRDPRQLQSALAERL PGWMVPKRIFLLDALPLTANGKIDYQTLKRCHTPEAENRTEADLPLGDIEKQVAVIWQPLLSMGAVSRETDFFQHGGDSL LATRLIGQLHQAGYEARLSDLFNHPRLADFAATLRKTDLPVEQPFVHSPEERYRPFALTDVQQAYLVGRQPGFALGGVGS HFFVEFEIADLDIHRLEKVWNRLIARHDMLRAVVRDGQQRVLEQTPPWVIPAHILHSPEEALQVRDRLAHQVLNPEVWPV FDLQVGFVDGMPARLWLCLDNLLLDGLSMQILLSELEHGYRYPQQLPPPLPITFRDYLQQPALRTPNPDSLAWWQTQLDD IPPAPALPLRCLPQDVETPRFARLYGAMDSARWRRLKQRAADAHLTPSAVLLSVWSTVLAAWSAQPDFTLNLTLFDRRPL HPQINQILGDFTSLMLLSWHPGESWLQSARLLQQRLSESLNHRDVSAIRVMRQLARRQNVPAVPMPVVFTSALGFEQDNF LARRNLLKPVWGISQTPQVWLDHQVYESEGELRFNWDFVAALFPDGQVERQFAQYCALLNRMAEDDSSWQLPLADLVPPL KVTERRARRLRPERAQPRIAADKSSVSLICDTFREVVGEPVAPAENFFEAGATSLNLVQLHVLLQRHEFATLTLLDLFTH PSPVALANYLAGVALEEKTKRVRPVRRRQRRI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| irp2 | YP_002346902.1 | yersiniabactin biosynthetic protein | Virulence | HPI | Protein | 0.0 | 88 |
| irp2 | NP_669706.1 | HMWP2 nonribosomal peptide synthetase | Virulence | HPI | Protein | 0.0 | 88 |
| irp2 | YP_070124.1 | yersiniabactin biosynthetic protein | Virulence | HPI | Protein | 0.0 | 88 |
| irp2 | YP_853075.1 | yersiniabactin biosynthetic protein | Virulence | PAI IV APEC-O1 | Protein | 0.0 | 88 |
| irp2 | NP_993007.1 | yersiniabactin biosynthetic protein | Virulence | HPI | Protein | 0.0 | 88 |
| irp2 | CAA21390.1 | - | Virulence | HPI | Protein | 0.0 | 88 |
| irp2 | YP_001006815.1 | yersiniabactin biosynthetic protein | Virulence | HPI | Protein | 0.0 | 87 |
| PMI2599 | YP_002152317.1 | non-ribosomal peptide synthase | Not tested | Not named | Protein | 0.0 | 41 |
