Gene Information

Name : A225_2651 (A225_2651)
Accession : YP_006498366.1
Strain : Klebsiella oxytoca E718
Genome accession: NC_018106
Putative virulence/resistance : Resistance
Product : Tetracycline efflux protein TetA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2801520 - 2802725 bp
Length : 1206 bp
Strand : -
Note : -

DNA sequence : 
ATGAATAGTTCGACAAAGATCGCATTGGTAATTACGTTACTCGATGCCATGGGGATTGGCCTTATCATGCCAGTCTTGCC
AACGTTATTACGTGAATTTATTGCTTCGGAAGATATCGCTAACCACTTTGGCGTATTGCTTGCACTTTATGCGTTAATGC
AGGTTATCTTTGCTCCTTGGCTTGGAAAAATGTCTGACCGATTTGGTCGGCGCCCAGTGCTGTTGTTGTCATTAATAGGC
GCATCGCTGGATTACTTATTGCTGGCTTTTTCAAGTGCGCTTTGGATGCTGTATTTAGGCCGTTTGCTTTCAGGGATCAC
AGGAGCTACTGGGGCTGTCGCGGCATCGGTCATTGCCGATACCACCTCAGCTTCTCAACGCGTGAAGTGGTTCGGTTGGT
TAGGGGCAAGTTTTGGGCTTGGTTTAATAGCGGGGCCTATTATTGGTGGTTTTGCAGGAGAGATTTCACCGCATAGTCCC
TTTTTTATCGCTGCGTTGCTAAATATTGTCGCTTTCCTTGTGGTTATGTTTTGGTTCCGTGAAACCAAAAATACACGTGA
TAATACAGATACCGAAGTAGGGGTTGAGACGCAATCGAATTCGGTATACATCACTTTATTTAAAACGATGCCCATTTTGT
TGATTATTTATTTTTCAGCGCAATTGATAGGCCAAATTCCCGCAACGGTGTGGGTGCTATTTACCGAAAATCGTTTTGGA
TGGAATAGCATGATGGTTGGCTTTTCATTAGCGGGTCTTGGTCTTTTACACTCAGTATTCCAAGCCTTTGTGGCAGGAAG
AATAGCCACTAAATGGGGCGAAAAAACGGCAGTACTGCTCGGATTTATTGCAGATAGTAGTGCATTTGCCTTTTTAGCGT
TTATATCTGAAGGTTGGTTAGTTTTCCCTGTTTTAATTTTATTGGCTGGTGGTGGGATCGCTTTACCTGCATTACAGGGA
GTGATGTCTATCCAAACAAAGAGTCATCAGCAAGGTGCTTTACAGGGATTATTGGTGAGCCTTACCAATGCAACCGGTGT
TATTGGCCCATTACTGTTTGCTGTTATTTATAATCATTCACTACCAATTTGGGATGGCTGGATTTGGATTATTGGTTTAG
CGTTTTACTGTATTATTATCCTGCTATCGATGACCTTCATGTTAACCCCTCAAGCTCAGGGGAGTAAACAGGAGACAAGT
GCTTAG

Protein sequence : 
MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFGVLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIG
ASLDYLLLAFSSALWMLYLGRLLSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
FFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYFSAQLIGQIPATVWVLFTENRFG
WNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKTAVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQG
VMSIQTKSHQQGALQGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQAQGSKQETS
A

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA(B) AAL08445.1 tetracycline resistance protein TetA(B) Not tested SRL Protein 3e-163 100
tetB AEA34667.1 tetracycline resistance determinant Not tested Not named Protein 3e-163 99
tetA(B) AEZ06045.1 tetracycline efflux protein Not tested Tn6167 Protein 4e-163 99
BJAB07104_00277 YP_008207742.1 Permeases of the major facilitator superfamily Not tested AbaR25 Protein 2e-162 99
BJAB0868_00281 YP_008211607.1 Permeases of the major facilitator superfamily Not tested AbaR26 Protein 2e-162 99
tetA(B) AEQ20905.1 tetracycline resistance protein Not tested Tn6166 Protein 2e-162 99
tetA YP_005797160.1 tetracycline resistance protein, class G (TETA(G)) Not tested AbaR4e Protein 3e-159 99
ABZJ_00260 YP_005524216.1 Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) Not tested AbaR22 Protein 6e-163 99
tetA(B) AFH57202.1 tetracycline resistance protein Not tested AbaR4a Protein 4e-163 99
tet(H) YP_005176248.1 tetracycline efflux protein, class H Not tested ICEPmu1 Protein 3e-77 54
tetA CAJ77034.1 Tetracycline resistance protein Not tested AbaR1 Protein 7e-85 52
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 1e-81 51
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 1e-81 51
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 1e-81 51
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 1e-81 51
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 7e-70 48
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 7e-70 48
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 9e-70 48
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 7e-70 48
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 3e-70 48
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 4e-70 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA NC_010558.1.6275971. Protein 2e-163 100
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA V00611.gene.p01 Protein 4e-162 99
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AB084246.gene.p01 Protein 1e-163 99
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA L06798.gene.p01 Protein 2e-91 63
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AJ250203.gene.p01 Protein 3e-82 59
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA Y19116.gene.p01 Protein 1e-78 55
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA L06940.gene.p01 Protein 1e-79 55
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA Y15510.gene.p01 Protein 4e-78 54
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA CP004022.1.gene2534. Protein 1e-78 54
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AF038993.gene.p01 Protein 9e-79 54
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA NC_010410.6002612.p0 Protein 4e-85 52
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AF133140.gene.p01 Protein 4e-85 52
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AF133139.gene.p01 Protein 2e-83 51
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA NC_011586.7045189.p0 Protein 3e-66 48
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AF534183.gene.p01 Protein 2e-70 48
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA NC_010410.6002597.p0 Protein 2e-70 48
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA CP001485.1.gene2821. Protein 2e-70 48
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA Y19114.gene.p01 Protein 7e-69 47
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA X75761.gene.p01 Protein 6e-70 47
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AF070999.gene.p01 Protein 1e-67 46
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AF121000.gene.p01 Protein 2e-62 45
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AY264780.2.gene3.p01 Protein 2e-62 44
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AJ420072.gene.p01 Protein 5e-59 44
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA AY743590.gene.p01 Protein 1e-59 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_2651 YP_006498366.1 Tetracycline efflux protein TetA VFG1036 Protein 1e-163 100