Gene Information

Name : A225_1953 (A225_1953)
Accession : YP_006497683.1
Strain : Klebsiella oxytoca E718
Genome accession: NC_018106
Putative virulence/resistance : Resistance
Product : mercuric ion reductase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2059910 - 2061532 bp
Length : 1623 bp
Strand : -
Note : -

DNA sequence : 
GTGCCCGGCGTGCAATCAGCGGATGTCTCCTACGCCAAGGGCAGCGCCAAGCTCGCCATTGAGGTCGGCACGTCACCCGA
CGCGCTGACGGCCGCTGTAGCTGGACTCGGTTATCGGGCCACGCTGGCCGATGCCCCCTCAGTTTCGACGCCGGGCGGAT
TGCTCGACAAGATGCGCGATCTGCTGGGCAGAAACGACAAGACGGGTAGCAGCGGCGCATTGCATATCGCCGTCATCGGC
AGCGGCGGGGCCGCGATGGCAGCGGCGCTGAAGGCCGTCGAGCAAGGCGCACGTGTCACGCTGATCGAGCGCGGCACCAT
CGGCGGCACCTGCGTCAATGTCGGTTGTGTGCCGTCCAAGATCATGATCCGCGCCGCCCATATCGCCCATCTGCGCCGGG
AAAGCCCGTTCGATGGCGGCATCGCCGCTACCACGCCGACCATCCAGCGCACGGCGCTGCTGGCCCAGCAGCAGGCCCGC
GTCGATGAACTGCGCCACGCCAAGTACGAAGGCATCTTGGAGGGCAATCCGGCGATCACTGTGCTGCACGGCTCCGCCCG
CTTTAAGGACAATCGCAACCTGATCGTGCAACTCAACGACGGCGGCGAGCGCGTGGTGGCATTCGACCGCTGCCTGATCG
CCACCGGCGCGAGCCCGGCCGTGCCGCCGATTCCCGGCCTGAAAGACACTCCGTACTGGACTTCCACTGAAGCGCTGGTC
AGCGAGACGATTCCTAAGCGCCTGGCCGTGATTGGCTCATCAGTGGTGGCGCTGGAGCTGGCGCAGGCGTTCGCCCGACT
CGGAGCGAAGGTGACGATCCTGGCTCGCAGCACGCTGTTCTTCCGCGAAGACCCAGCTATAGGCGAAGCCGTCACGGCCG
CATTCCGCATGGAGGGCATCGAGGTGAGGGAACACACCCAGGCCAGCCAGGTCGCGTATATCAATGGTGAAGGGGACGGC
GAATTCGTGCTCACCACGGCGCACGGCGAACTGCGCGCCGACAAGCTGCTGGTCGCCACCGGCCGCGCGCCCAACACACG
CAAGCTGGCACTGGATGCGACGGGCGTCACGCTCACCCCGCAAGGCGCTATCGTCATCGACCCCGGCATGCGTACAAGCG
TGGAACACATCTACGCCGCAGGCGACTGCACCGACCAGCCGCAGTTCGTCTATGTGGCGGCAGCGGCCGGCACTCGCGCC
GCGATCAACATGACCGGCGGTGACGCGGCCCTGAACCTGACCGCGATGCCGGCCGTGGTGTTCACCGACCCGCAAGTGGC
GACCGTAGGCTACAGCGAGGCGGAAGCGCACCATGACGGCATCAAAACTGATAGTCGCACGCTAACGCTGGACAACGTGC
CGCGCGCGCTCGCCAACTTCGACACGCGCGGCTTCATCAAACTGGTGGTTGAAGAAGGCAGCGGACGACTGATCGGCGTG
CAGGCAGTGGCCCCGGAAGCGGGCGAACTGATCCAGACGGCCGCACTGGCGATTCGCAACCGGATGACGGTGCAGGAACT
GGCCGACCAGTTGTTCCCCTACCTGACGATGGTCGAAGGGTTGAAGCTCGCGGCGCAGACCTTCAACAAGGATGTGAAGC
AGCTTTCCTGCTGCGCCGGGTGA

Protein sequence : 
MPGVQSADVSYAKGSAKLAIEVGTSPDALTAAVAGLGYRATLADAPSVSTPGGLLDKMRDLLGRNDKTGSSGALHIAVIG
SGGAAMAAALKAVEQGARVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESPFDGGIAATTPTIQRTALLAQQQAR
VDELRHAKYEGILEGNPAITVLHGSARFKDNRNLIVQLNDGGERVVAFDRCLIATGASPAVPPIPGLKDTPYWTSTEALV
SETIPKRLAVIGSSVVALELAQAFARLGAKVTILARSTLFFREDPAIGEAVTAAFRMEGIEVREHTQASQVAYINGEGDG
EFVLTTAHGELRADKLLVATGRAPNTRKLALDATGVTLTPQGAIVIDPGMRTSVEHIYAAGDCTDQPQFVYVAAAAGTRA
AINMTGGDAALNLTAMPAVVFTDPQVATVGYSEAEAHHDGIKTDSRTLTLDNVPRALANFDTRGFIKLVVEEGSGRLIGV
QAVAPEAGELIQTAALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 99
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 99
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 99
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 92
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 92
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 92
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 85
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 85
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 79
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 76
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 7e-78 43
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 6e-78 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A225_1953 YP_006497683.1 mercuric ion reductase BAC0652 Protein 0.0 86
A225_1953 YP_006497683.1 mercuric ion reductase BAC0653 Protein 0.0 81
A225_1953 YP_006497683.1 mercuric ion reductase BAC0650 Protein 4e-163 71
A225_1953 YP_006497683.1 mercuric ion reductase BAC0651 Protein 3e-78 43
A225_1953 YP_006497683.1 mercuric ion reductase BAC0224 Protein 1e-76 43