Gene Information

Name : guaA (SMUGS5_04700)
Accession : YP_006490253.1
Strain : Streptococcus mutans GS-5
Genome accession: NC_018089
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 993908 - 995461 bp
Length : 1554 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGACTGATATTAAAGATATTCAAAAAATTATCGTACTTGACTACGGCAGTCAGTACAATCAGCTAATCGCACGCCGCAT
TCGTGAATTTGGTATTTTTTCTGAATTGAGAAGCCATAAGGTAACAGCCGACGAAGTCCGTGCTATCAATCCAATTGGTA
TTGTCCTTTCAGGAGGACCAAGTTCAGTTTATGCTGAAGATGCCTTTGACATTGATAAGGAAATCCTTGATCTTGGAATC
CCCGTTTTAGGTATTTGTTATGGTATGCAGCTTCTTACAGAAAAACTTGGCGGTAAAGTTGTTCCTGCTGGACAAACTGG
CAATAGTGAATATGGTCAGTCTACCCTTCATTTGATAGAAAATTCAGAGCTTTTTAAGGAAACTCCTGCTGAACAAACTG
TTTTGATGAGCCATGGCGATGCTGTTACTGAAATTCCCGAAGGCTTTCAATTGGTTGGCGAATCAAGCGACTGCCCTTAT
GCTGCCATTGAAAATGTCGAAAAGAAAATCTTTGGCATTCAATTTCACCCAGAAGTTCGTCATACGGAATATGGTAATGC
GATTTTACGCAATTTTGCTTTTAATGTTTGTAAAGCCAAAGGTGATTGGTCAATGGACAGTTTCATTGATATGGAAATTG
AAAAAATCCGTGAACAAGTTGGTAATCGTAAGGTTCTTCTAGGGCTTTCGGGCGGTGTGGACTCTTCTGTTGTTGGCGTG
CTTTTGCAAAAAGCTATAGGTGACCAATTAACCTGTATCTTCGTTGATCATGGCCTTCTTCGTAAGGGTGAAGGCGATCA
GGTTATGGAAATGTTGGGTGGTAGATTTGGACTCAATATTATTCGTGTTGATGCTTCCAAACGCTTTTTGGATCTTCTTG
CTGGTATTGATGATCCTGAGAAAAAGCGTAAAATCATTGGGAATGAATTTGTCTATGTTTTTGATGATGAAGCCAGCAAA
CAAAAAGGCGTTGATTTCTTGGCACAAGGAACGCTTTATACAGATGTCATCGAATCCGGCACAGAAACAGCCCAAACCAT
TAAATCACACCACAATGTCGGTGGTCTTCCAGAAGACATGCAGTTTGAATTAATAGAGCCGTTAAACACACTGTTCAAGG
ATGAAGTTCGTACTCTGGGGACTGCTTTAGGAATGCCAGATGAAATCGTTTGGCGGCAGCCCTTCCCAGGACCTGGACTT
GCTATTCGTGTGATGGGAGAAATTACTGCTGAAAAACTTGAAACGGTTCGTGAATCTGACGCTATTTTACGCGAAGAAAT
TGCTGCAGCAGGCCTGAATCGTGATATTTGGCAATATTTTACTGTCAATACTGGCGTTCGTTCAGTCGGAGTTATGGGAG
ATGGTCGTACCTATGACTATACCATTGCTATTCGCGCCATCACTTCTATTGACGGCATGACAGCAGACTTTGCCCGTATT
CCTTGGGAGGTTCTCCAAAAGATCTCTGTTCGTATTGTCAACGAAGTGGAACACGTCAACCGTATCGTCTACGACATTAC
CAGCAAACCACCAGCAACTGTTGAGTGGGAATAA

Protein sequence :
MTDIKDIQKIIVLDYGSQYNQLIARRIREFGIFSELRSHKVTADEVRAINPIGIVLSGGPSSVYAEDAFDIDKEILDLGI
PVLGICYGMQLLTEKLGGKVVPAGQTGNSEYGQSTLHLIENSELFKETPAEQTVLMSHGDAVTEIPEGFQLVGESSDCPY
AAIENVEKKIFGIQFHPEVRHTEYGNAILRNFAFNVCKAKGDWSMDSFIDMEIEKIREQVGNRKVLLGLSGGVDSSVVGV
LLQKAIGDQLTCIFVDHGLLRKGEGDQVMEMLGGRFGLNIIRVDASKRFLDLLAGIDDPEKKRKIIGNEFVYVFDDEASK
QKGVDFLAQGTLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRTLGTALGMPDEIVWRQPFPGPGL
AIRVMGEITAEKLETVRESDAILREEIAAAGLNRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFARI
PWEVLQKISVRIVNEVEHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-174 70
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-174 70
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-174 70
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-120 51