Gene Information

Name : SMUGS5_04230 (SMUGS5_04230)
Accession : YP_006490163.1
Strain : Streptococcus mutans GS-5
Genome accession: NC_018089
Putative virulence/resistance : Virulence
Product : Clp-like ATP-dependent protease, ATP-binding subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 895201 - 897306 bp
Length : 2106 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGCAAATTTTAATGGACGCGATCCTTTTGGAAATATGGACGATATTTTTAATCAATTAATGGGTAATATGGGGGGATA
CAACTCTGAAAACCGTCGATATTTAATTAACGGTCGTGAAGTAAGTCCCGAAGAATTCGCACAATACAGACAAACAGGTA
AGCTTCCTGGCAATCCAGAAATACAGCAAGCTCAAGCTGCTGCTAGAACTCCAAAAGAAGACAGTATTTTGACTAAGCTT
GGTAACAATTTAACCGAAGAAGCCAGACAAGGTAACCTTGATCCTGTTATTGGACGGAATAAAGAAATTCAAGAAACTGC
TGAGATCTTAGCTCGGCGGACTAAAAACAATCCTGTTCTGGTCGGTGATGCCGGTGTTGGTAAAACAGCTGTCGTTGAAG
GCTTAGCACAGGCTATTGTTAACGGTGATGTCCCTGCCAGTATTAAAAATAAGGAAGTTATTTCTATTGATATTTCAGGA
TTAGAAGCTGGTACACAATACCGTGGTGCTTTCGAAGAAAATATTCAAAACTTGGTTAAAGAAGTCAAAGAAGCTGGCAA
TATCATCCTCTTCTTTGATGAAATTCATCAAATTTTAGGTGCTGGTTCAACTGGTGGTGACAGTGGTTCTAAAGGTTTGG
CAGACATTATCAAACCTGCTTTATCTCGCGGTGAATTGACTGTTATCGGTGCTACTACGCAAGATGAATACCGCAATACC
ATTATGAAAAACGCTGCATTGGCACGTCGTTTCAACGAAGTCAAAGTAAATGCACCTTCTGCTGAGGATACTTACGAAAT
TTTAAAAGGTATTTCAGCTCTCTACGAACAACATCATAATGTTATTTTGCCTAAGGAAGTTTTAAAAGCTGCTGTTGACT
TATCCGTACAATACATCCCGCAACGCAGTCTGCCTGATAAGGCCATTGACCTTGTTGATATGACAGCTGCTCATCTGGCT
GCTCAACATCCAGCAACTGATGTTAAGACACTTGAAAAAGAAATTCAAACTGAAAAAGATAAACAACAAGCTGCTGCTGA
AAAAGAAGATTATGAGGAAGCTCTTAAATCAAAAACTAAAATTGATAAACTGCAAGCACAAATTGACAATCATACTGAAG
GGCAAAAGGTTACTGCTACTATCAACGATGTGGCTGAGGCAGTTGAACGTTTGACAGGTATCCCTGTTTCGCAAATGGGA
AGCAGTGACATTGAACGTCTAAAAGAAATGAATTCTCGTCTCAAAGGCAAAGTTATTGGTCAAGATGAAGCTGTTGAAGC
TGTTTCACGCGCTATTCGCCGTAACCGTGCTGGTTTTGATGAAGGCAACCGTCCAATCGGCAGTTTCCTTTTTGTCGGAC
CTACTGGTGTTGGTAAAACAGAATTGGCTAAGCAGTTAGCCTTGGATATGTTTGGTTCTAAAGACTCTATTATCCGTCTT
GATATGTCAGAGTACAGTGATCGTACAGCTGTTTCCAAATTGATTGGTACTACTGCCGGTTATGTCGGCTATGATGATAA
CAGCAATACATTGACTGAACGTGTTCGCCGCAATCCTTATTCTATCGTTTTACTTGATGAGATTGAAAAGGCTGACTCTC
AAGTCATCACTCTTCTCCTTCAAGTATTGGATGATGGTCGTTTGACAGACGGACAAGGTAATACCATTAACTTTAAGAAT
ACCGTGATTATTGCAACTTCTAATGCTGGTTTTGGTAATGAAGCATTAACTGGTCAGGAAGATAAGGACATGAAGATCAT
GGATCGCATTGCCCCTTACTTCCGTCCCGAGTTTTTAAACCGTTTCAATGCAGTCATTGAATTCTCTCACTTAAGCAAAG
AAGACTTGGATGAAATCGTTAATCTCATGCTATCTGAAGTGAATACCACGCTTGCTAAGAAAGGAATTGATCTTGTTGTC
AGTGACAGCGCCAAGGCACATTTGATTGAAGAAGGTTATGACGAAGCAATGGGTGTTCGTCCATTACGCCGAGTTATCGA
GCAAGAAATTCGTGATAAAGTAACTGACTTCTATCTTGATCATACAGATGTTAAACATCTCAAAGCTGAAATGCAAGATG
ACAAATTGATTATTGAAGAAGCTTAA

Protein sequence :
MANFNGRDPFGNMDDIFNQLMGNMGGYNSENRRYLINGREVSPEEFAQYRQTGKLPGNPEIQQAQAAARTPKEDSILTKL
GNNLTEEARQGNLDPVIGRNKEIQETAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPASIKNKEVISIDISG
LEAGTQYRGAFEENIQNLVKEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADIIKPALSRGELTVIGATTQDEYRNT
IMKNAALARRFNEVKVNAPSAEDTYEILKGISALYEQHHNVILPKEVLKAAVDLSVQYIPQRSLPDKAIDLVDMTAAHLA
AQHPATDVKTLEKEIQTEKDKQQAAAEKEDYEEALKSKTKIDKLQAQIDNHTEGQKVTATINDVAEAVERLTGIPVSQMG
SSDIERLKEMNSRLKGKVIGQDEAVEAVSRAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKDSIIRL
DMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADSQVITLLLQVLDDGRLTDGQGNTINFKN
TVIIATSNAGFGNEALTGQEDKDMKIMDRIAPYFRPEFLNRFNAVIEFSHLSKEDLDEIVNLMLSEVNTTLAKKGIDLVV
SDSAKAHLIEEGYDEAMGVRPLRRVIEQEIRDKVTDFYLDHTDVKHLKAEMQDDKLIIEEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 6e-135 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SMUGS5_04230 YP_006490163.1 Clp-like ATP-dependent protease, ATP-binding subunit VFG0080 Protein 1e-152 48
SMUGS5_04230 YP_006490163.1 Clp-like ATP-dependent protease, ATP-binding subunit VFG0079 Protein 3e-141 45