Gene Information

Name : SMUGS5_08600 (SMUGS5_08600)
Accession : YP_006490987.1
Strain : Streptococcus mutans GS-5
Genome accession: NC_018089
Putative virulence/resistance : Virulence
Product : response regulator GcrR for glucan-binding protein C
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1784625 - 1785317 bp
Length : 693 bp
Strand : -
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGATACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTTATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAGACTAATGTTGTCGATGTTTATATTTGCTATCTTCGTGGGAAGATTGATGTTCCTGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Protein sequence : 
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYICYLRGKIDVPGKESYIQTVRGMGYIIRENN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 9e-37 42
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 9e-36 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C HE999704.1.gene1528. Protein 7e-56 60
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C NC_002952.2859858.p0 Protein 1e-49 52
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C NC_007622.3794948.p0 Protein 1e-49 52
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C NC_003923.1003417.p0 Protein 1e-49 52
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C NC_013450.8614146.p0 Protein 1e-49 52
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C NC_002951.3238224.p0 Protein 1e-49 52
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C NC_007793.3914065.p0 Protein 1e-49 52
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C NC_002758.1121390.p0 Protein 1e-49 52
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C NC_010079.5776364.p0 Protein 1e-49 52
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C AE015929.1.gene1106. Protein 9e-46 52
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C BAC0197 Protein 2e-35 42
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C AE000516.2.gene3505. Protein 8e-32 42
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C NC_012469.1.7685629. Protein 8e-36 41
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C BAC0125 Protein 4e-35 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C VFG1389 Protein 1e-36 43
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C VFG0596 Protein 4e-37 42
SMUGS5_08600 YP_006490987.1 response regulator GcrR for glucan-binding protein C VFG1390 Protein 6e-38 41