Gene Information

Name : SMUGS5_05290 (SMUGS5_05290)
Accession : YP_006490363.1
Strain : Streptococcus mutans GS-5
Genome accession: NC_018089
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1113114 - 1114616 bp
Length : 1503 bp
Strand : -
Note : COG0469 Pyruvate kinase

DNA sequence : 
ATGAATAAACGCGTAAAAATTGTTGCAACTTTAGGTCCAGCGGTAGAAATCCGTGGTGGTAAAAAATTTGGTGAAGATGG
CTATTGGGGTGAAAAGCTTGATGTTGAAGCTTCAGCAGCAAAAATTGCTGAATTGATTACAGAAGGAGCCAATGTTTTTC
GTTTTAACTTTTCACATGGTGACCATGCTGAGCAAGGTGAACGTATGGCGACTGTACGTCGCGCGGAAGAATTGGCACGT
CAAAAGGTTGGATTCCTTCTTGATACTAAAGGACCTGAAATGCGTACAGAATTGTTTGCAGATGGTGTCAAAGAATATGA
ATATAAGACTGGTGATAAACTTCGTATAGCAACTAAACAAGGCATTGAATCAACTAAGGATGTCATTGCTTTAAATGTTG
CAGGCGGTCTTGATATTTATGATGATGTTGCTGTCGGTCAGACTATTCTTATTGATGATGGGAAACTTGGCCTTACAGTA
ACCGCTAAAGATATTACAACTCGCGAGTTTGAAGTAACCGTTGAAAATGATGGTATTATTGCTAAACAAAAAGGTGTCAA
TATTCCTAATACTAAAATTCCTTTCCCAGCACTTGCTGAGCGTGATAATGCAGATATTCGCTTTGGTTTGGAACAAGGTC
TTAACTTTATTGCTATTTCTTTTGTTCGTACTGCTAAGGATGTTAATGAAGTTCGTCAAATTTGTAAAGAAACAGGTAAC
GAACACGTAAAACTTTTTGCTAAAATTGAAAATCAACAAGGTATTGATAACATTGATGAAATCATTGATGCAGCTGATGG
TATCATGATTGCTCGCGGTGACATGGGTATTGAAGTGCCGTTTGAAATGGTTCCAGTATATCAAAAAATGATTATCACGA
AAGTTAATGCAGCAGGGAAGTCAGCTATCACAGCAACAAATATGCTTGAAACAATGACTGACAAACCACGTGCAACACGT
TCCGAAGTCTCTGATGTCTTTAATGCTGTCATTGATGGTACTGATGCAACAATGCTTTCTGGTGAATCAGCTAATGGTAA
GTATCCAGTTGAAGCTGTTCGTACCATGGCAACAATTGATAAGAATGCTCAAACACTTCTTAATGAATATGGCCGTTTGA
ATTCAGATAATTTGCCACGTACCAACAAGACTGAAGTTGTCGCTTCAGCTGTTAAAGATGCGACTAAATCAATGGATATT
AAATTGGTTGTTACAATTACAGAATCTGGTAACACAGCTCGTTTAATTTCAAAATACCGTCCGGATGCAGATATCTTAGC
TTTAACATTTGATGAAAAAGTCCAAAAATCATTGATGATTAACTGGGGAGTTATTCCAATCTTAACAGAAAAACCTGCAT
CTACTGATGATATGTTTGAAATTGCAGAAAAAGCAGCTCTTAAATCAGGTTTGGTAGAGTCTGGTGACAACATCGTTATT
GTTGCTGGTGTACCGGTTGGATCTGGTGGTACCAATACTATGCGTGTTCGTACCGTTCAATAA

Protein sequence : 
MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAAKIAELITEGANVFRFNFSHGDHAEQGERMATVRRAEELAR
QKVGFLLDTKGPEMRTELFADGVKEYEYKTGDKLRIATKQGIESTKDVIALNVAGGLDIYDDVAVGQTILIDDGKLGLTV
TAKDITTREFEVTVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVNEVRQICKETGN
EHVKLFAKIENQQGIDNIDEIIDAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKSAITATNMLETMTDKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLNSDNLPRTNKTEVVASAVKDATKSMDI
KLVVTITESGNTARLISKYRPDADILALTFDEKVQKSLMINWGVIPILTEKPASTDDMFEIAEKAALKSGLVESGDNIVI
VAGVPVGSGGTNTMRVRTVQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-70 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-70 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-70 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-69 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SMUGS5_05290 YP_006490363.1 pyruvate kinase VFG0479 Protein 1e-70 43