Gene Information

Name : guaA (EHR_04745)
Accession : YP_006486802.1
Strain : Enterococcus hirae ATCC 9790
Genome accession: NC_018081
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 890659 - 892224 bp
Length : 1566 bp
Strand : +
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
GTGACAAACGTTGCCGACATGACAAACGTTGAAAAGATTATCGTATTAGACTACGGTAGCCAGTATAACCAATTGATTAC
ACGACGCATCCGTGATTTAGGAGTTTTTTCTGAATTATTGAGCCATCGGGTTTCTGCTGAAGAAGTAAAAGCAATGAATC
CAAAAGGAATCATTCTTTCCGGTGGTCCTAACAGTGTGTATGATGAAAATGCTTTTGGAATCGATCCAGAAATCTTTAAC
TTAGGGATTCCTGTATTGGGTATTTGCTACGGTATGCAATTGATTACGTATAAGCTAGGTGGGAAAGTTGAACCAGCTAA
AAACCGTGAATACGGAAAAGCTCAGTTAGAAGTAACCAGTGACGATGCAGTATTGTTCAATGACACACCTAAACAACAAA
CCGTTTGGATGAGCCACGGGGACTTAGTAACCCAAGTTCCTGAAGGATTTGAAATCGTTGGTACAAGTAAAGACTGCCCG
ATCGCATCCATCCAAGACACAAAACGTAATTTCTATGGTATCCAATTCCATGCAGAAGTTCGTCATTCTGAATACGGAAT
CGAATTACTCCGTCATTTTGCTTTTGATGTTTGTCATTGTGAAGGAAACTGGACAATGAATAACTTCATCGATATGCAAA
TCGAAAAAATTCGTGAACAAGTTGGCGATAAAAAAGTATTGCTTGGACTTTCTGGCGGCGTGGATTCTAGTGTCGTTGGT
GTTCTTTTACAAAAAGCAATCGGTGATCAGCTAACTTCCATCTTTGTTGACCATGGTTTATTGCGTAAAGGCGAAGCAGA
CCAAGTAATGGAAAGCTTAGGCGGGAAATTTGGTCTAAATATTATCAAAGTGGATGCAAGAAAACGTTTCTTAGACAAGT
TAGCCGGCGTTTCTGATCCTGAGCAAAAACGTAAAATCATTGGTAATGAATTTGTGTATGTTTTTGATGATGAAGCAACA
AAATTAGCGGGAGAAGAAGGAATTGCTTTCTTAGCCCAAGGAACACTTTATACTGATGTGATCGAAAGTGGAACGGAAAC
TGCTCAAACGATCAAATCTCACCATAACGTGGGTGGACTACCAGAAGACATGCAATTCCAATTGATCGAACCTTTGAACA
CATTATTCAAAGATGAAGTCCGTGAATTAGGAACACAACTAGGAATGCCAGATTCAATCGTTTGGCGTCAACCTTTCCCA
GGTCCTGGTCTAGGTATCCGTGTCTTGGGTGAAATCAGTGAAGAAAAACTAGAAATCGTCCGTGAATCAGATGCGATCTT
ACGTGAAGAAATCGCAGCAGCTGGCTTAGATCGTGACATTTGGCAATATTTCACTGTTCTACCAGGAATCCGCTCTGTCG
GTGTAATGGGCGATGGCCGTACTTACGACTATACAGTAGGTATCCGTGCAGTCACTTCTATTGATGGGATGACAGCAGAC
TTTGCCCGTATCCCATGGGATGTTTTACAAAAAATCTCTGTCCGCATCGTAAACGAAGTCGCTCACGTCAACCGTATCGT
GTACGACATCACTTCTAAACCACCTGCAACTGTGGAGTGGGAATAA

Protein sequence :
MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRVSAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFN
LGIPVLGICYGMQLITYKLGGKVEPAKNREYGKAQLEVTSDDAVLFNDTPKQQTVWMSHGDLVTQVPEGFEIVGTSKDCP
IASIQDTKRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMNNFIDMQIEKIREQVGDKKVLLGLSGGVDSSVVG
VLLQKAIGDQLTSIFVDHGLLRKGEADQVMESLGGKFGLNIIKVDARKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEAT
KLAGEEGIAFLAQGTLYTDVIESGTETAQTIKSHHNVGGLPEDMQFQLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFP
GPGLGIRVLGEISEEKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSIDGMTAD
FARIPWDVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-179 74
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-179 74
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-179 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-124 51