Gene Information

Name : EHR_02300 (EHR_02300)
Accession : YP_006486333.1
Strain : Enterococcus hirae ATCC 9790
Genome accession: NC_018081
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator VicR
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 430730 - 431434 bp
Length : 705 bp
Strand : -
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
ATGAAAAAGATTTTAGTTGTCGATGACGAAAAGCCGATTTCGGATATCGTCAAATTCAATTTAGCCAAGGAAGGCTATGA
TGTTTATACTGCATATGACGGGGAAGAAGCCTTAGAAAAAGTCACTGAGGTGGAACCTGATTTGATCTTGCTAGATTTGA
TGTTACCAAAAATGGATGGCTTAGAAGTCGCGCGTGAAGTACGGAAAACCTACGACATGCCGATCATTATGGTGACTGCA
AAAGATTCTGAAATCGATAAGGTATTAGGACTGGAATTAGGTGCTGATGATTACGTGACGAAGCCTTTTTCTAATCGTGA
ACTAGTGGCTCGAGTGAAAGCCAATCTTCGTCGTGGCGCAACTGCTACCAAAGAAGTAGAAGAAATTGCCCCTTCTGAAC
TCGTGATTGGTGACCTGACGATTCATCCGGATGCTTATATGGTAACGAAACGAGGCGAAACAATTGAATTAACGCATCGT
GAATTTGAATTGCTTTTTTACTTAGCAAAACACATCGGACAAGTGATGACACGAGAGCATTTGCTGCAAACCGTGTGGGG
CTATGATTACTTTGGTGATGTGCGAACTGTAGATGTAACCGTGAGACGTCTACGCGAAAAAATTGAAGATAATCCAAGTC
ATCCTAATTATTTAGTGACACGGCGAGGTGTTGGTTACTATTTACGTAACCAGGAACAGGAGTAA

Protein sequence : 
MKKILVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVTEVEPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTA
KDSEIDKVLGLELGADDYVTKPFSNRELVARVKANLRRGATATKEVEEIAPSELVIGDLTIHPDAYMVTKRGETIELTHR
EFELLFYLAKHIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYLVTRRGVGYYLRNQEQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 2e-33 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_012469.1.7685629. Protein 2e-69 70
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_002952.2859905.p0 Protein 7e-53 57
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_013450.8614421.p0 Protein 7e-53 55
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_007793.3914279.p0 Protein 7e-53 55
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_002745.1124361.p0 Protein 7e-53 55
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_009782.5559369.p0 Protein 7e-53 55
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_002951.3237708.p0 Protein 7e-53 55
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_003923.1003749.p0 Protein 8e-53 55
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_007622.3794472.p0 Protein 5e-53 55
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_002758.1121668.p0 Protein 7e-53 55
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_009641.5332272.p0 Protein 7e-53 55
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR HE999704.1.gene2815. Protein 9e-49 53
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_012469.1.7686381. Protein 7e-43 50
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR AE016830.1.gene1681. Protein 6e-47 50
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR AE000516.2.gene3505. Protein 2e-36 48
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR FJ349556.1.orf0.gene Protein 3e-40 47
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR AF155139.2.orf0.gene Protein 1e-37 46
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR CP001138.1.gene4273. Protein 4e-34 46
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR BAC0533 Protein 1e-34 46
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR CP004022.1.gene3215. Protein 2e-38 46
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR CP000647.1.gene4257. Protein 1e-34 46
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR CP000034.1.gene3834. Protein 8e-34 45
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_002695.1.915041.p Protein 8e-34 45
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR HE999704.1.gene1528. Protein 5e-32 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_010079.5776364.p0 Protein 4e-36 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_002952.2859858.p0 Protein 4e-36 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_007622.3794948.p0 Protein 4e-36 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_003923.1003417.p0 Protein 4e-36 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_013450.8614146.p0 Protein 4e-36 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_002951.3238224.p0 Protein 4e-36 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_007793.3914065.p0 Protein 4e-36 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_002758.1121390.p0 Protein 4e-36 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR BAC0039 Protein 2e-30 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR CP000034.1.gene2186. Protein 2e-30 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_002695.1.916589.p Protein 2e-30 44
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR AF162694.1.orf4.gene Protein 1e-33 43
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR AM180355.1.gene1830. Protein 3e-39 43
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR AE015929.1.gene1106. Protein 9e-31 43
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR BAC0596 Protein 3e-29 43
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR CP001138.1.gene2239. Protein 3e-29 43
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_005054.2598277.p0 Protein 3e-36 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_014475.1.orf0.gen Protein 3e-36 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR AF130997.1.orf0.gene Protein 9e-37 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR DQ212986.1.gene4.p01 Protein 6e-39 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_010410.6002989.p0 Protein 2e-28 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_010400.5986590.p0 Protein 1e-27 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR NC_011595.7057856.p0 Protein 2e-28 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR CP004022.1.gene1676. Protein 5e-26 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR CP001918.1.gene3444. Protein 1e-29 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR EU250284.1.orf4.gene Protein 2e-37 41
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR CP000647.1.gene2531. Protein 1e-29 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR VFG1389 Protein 7e-30 46
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR VFG1390 Protein 4e-33 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR VFG1386 Protein 3e-34 42
EHR_02300 YP_006486333.1 DNA-binding response regulator VicR VFG1702 Protein 8e-34 41