Gene Information

Name : PADK2_28600 (PADK2_28600)
Accession : YP_006485683.1
Strain : Pseudomonas aeruginosa DK2
Genome accession: NC_018080
Putative virulence/resistance : Virulence
Product : betaine aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.8
Position : 6186161 - 6187633 bp
Length : 1473 bp
Strand : -
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGGCCCGATTCGAAGAACAGAAGCTCTACATTGGCGGTCGCTACGTGGAGGCCAGCAGTGGCGCCACCTTCGAGACCAT
CAATCCGGCCAACGGCGAAGTGCTCGCCAAGGTCCAGCGGGCTTCCAGGGAAGACGTCGAGCGGGCCGTGCAGAGCGCCG
TCGAGGGGCAGAAGGTGTGGGCGGCGATGACCGCCATGCAGCGCTCGCGCATTCTCCGTCGCGCCGTCGACATCCTCCGC
GAGCGCAACGACGAACTGGCTGCCCTGGAAACCCTGGATACCGGCAAGCCGCTGGCGGAAACCCGCTCGGTGGACATCGT
CACCGGCGCCGACGTGCTCGAGTACTACGCCGGCCTGGTCCCGGCCATCGAAGGCGAGCAGATTCCCCTGCGCGAAACCA
GTTTCGTCTACACCCGCCGCGAGCCGCTGGGCGTGGTCGCCGGCATTGGCGCCTGGAACTACCCGGTGCAGATCGCCCTG
TGGAAATCCGCCCCGGCCCTCGCTGCCGGCAACGCGATGATCTTCAAGCCCAGCGAAGTCACCCCGCTGACGGCCCTCAA
GCTGGCCGAGATCTACACCGAGGCCGGCGTGCCGGACGGCGTGTTCAACGTGCTCACCGGCAGCGGACGCGAAGTCGGCC
AGTGGCTGACCGAGCACCCGCTGATCGAGAAGATCTCCTTCACCGGTGGCACCTCCACCGGCAAGAAAGTCATGGCCAGC
GCTTCCAGCTCGTCGCTGAAGGAAGTGACCATGGAGCTGGGCGGCAAGTCCCCGCTGATCATCTTCCCCGACGCAGACCT
CGACCGCGCCGCCGACATCGCCGTCATGGCCAACTTCTTCAGCTCCGGCCAGGTCTGCACCAACGGCACCCGGGTGTTCA
TCCACCGTTCCCAGCAGGCTCGCTTCGAAGCCAAGGTACTGGAGCGCGTGCAGCGCATCCGTCTCGGCGACCCGCAGGAC
GAGAACACCAACTTCGGCCCGCTGGTCAGCTTCCCGCACATGGAAAGCGTGCTCGGCTACATCGAGTCCGGCAAGGCGCA
GAAGGCTCGCCTGCTGTGCGGCGGCGAGCGTGTGACCGATGGAGCGTTCGGCAAAGGCGCCTACGTCGCGCCGACCGTGT
TCACCGATTGCCGCGACGACATGACCATCGTCCGCGAGGAAATCTTCGGCCCGGTGATGAGCATCCTGGTCTATGACGAC
GAAGACGAGGCGATCCGCCGCGCCAACGATACCGAGTACGGCCTCGCCGCCGGCGTCGTGACCCAGGACCTGGCCCGCGC
CCACCGCGCCATCCATCGCCTGGAAGCCGGCATCTGCTGGATCAATACCTGGGGCGAGTCGCCGGCGGAAATGCCGGTCG
GCGGTTACAAGCAATCCGGTGTCGGTCGCGAGAACGGTCTCACCACCCTGGCTCATTACACTCGCATCAAGTCCGTGCAA
GTGGAGCTGGGCGACTACGCCTCGGTGTTCTGA

Protein sequence :
MARFEEQKLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSAVEGQKVWAAMTAMQRSRILRRAVDILR
ERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGLVPAIEGEQIPLRETSFVYTRREPLGVVAGIGAWNYPVQIAL
WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMAS
ASSSSLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFEAKVLERVQRIRLGDPQD
ENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTDGAFGKGAYVAPTVFTDCRDDMTIVREEIFGPVMSILVYDD
EDEAIRRANDTEYGLAAGVVTQDLARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSVQ
VELGDYASVF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-76 42
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-75 41
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-80 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-77 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-77 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-77 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-77 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PADK2_28600 YP_006485683.1 betaine aldehyde dehydrogenase VFG0082 Protein 1e-75 41