Gene Information

Name : ureC (PADK2_25830)
Accession : YP_006485131.1
Strain : Pseudomonas aeruginosa DK2
Genome accession: NC_018080
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 5564910 - 5566610 bp
Length : 1701 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAATCAGCAGACAAGCCTACGCCGACATGTTCGGCCCCACCGTCGGCGACCGCGTGCGCCTGGCCGACACCGACCT
GTGGATCGAGGTGGAACGGGACTTCACCGTCTATGGCGAGGAAGTGAAGTTCGGCGGCGGCAAGGTCATCCGCGACGGCA
TGGGCCAGAGCCAGCTGGGCGCGGCGCAGGTGGTCGACACGGTGATCACCAATGCGCTGATCCTCGACCACTGGGGCGTG
GTCAAGGCCGACGTCGGTCTCAAGGACGGGCGCATCCAGGCCATCGGCAAGGCCGGCAACCCGGACATCCAGCCCGGGGT
GAACATCGCCATCGGCGCCGGCACCGAGGTGATCGCCGGCGAGGGCATGATCCTCACCGCCGGCGGCATCGACACGCACA
TCCACTTCATCTGCCCGCAGCAGATCGAAGAGGCGCTGATGAGCGGGGTCACCACCATGATCGGCGGCGGCACCGGCCCC
GCCGCCGGGACCAACGCCACCACCTGCACCTCCGGTCCCTGGCACATGGCGCGGATGCTCCAGGCCGCCGACGCCTTCCC
GATGAACATCGGCTTCACCGGCAAGGGCAACGCCAGCCTGCCGCTGCCGCTGGAGGAGCAGGTGCTCGCCGGCGCCATCG
GCCTGAAGCTGCACGAGGACTGGGGCAGCACCCCGGCGGCGATCGACAACTGCCTGGAGGTCGCCGAGCGCCACGACATC
CAGGTGGCGATCCACACCGACACCCTCAACGAATCCGGCTTCGTCGAGACCACCCTCGGCGCCTTCAAGGGCCGCACCAT
CCACACCTACCACACCGAGGGCGCCGGCGGCGGCCACGCACCGGACATCATCAAGGCCTGCGGCTTCGCCAACGTGCTGC
CCAGCTCGACCAACCCGACACGGCCGTTCACCCGCAATACCATCGACGAGCACCTGGACATGCTGATGGTCTGCCACCAC
CTCGACCCGGCCATCGCCGAGGACGTGGCCTTCGCCGAGTCGCGCATCCGCCGCGAGACCATCGCCGCCGAGGACATCCT
CCACGACCTCGGCGCGTTCAGCATGATCAGCTCCGACAGCCAGGCCATGGGCCGGGTCGGCGAAGTGATCACGCGCACCT
GGCAGACCGCCGACAAGATGAAGCGCCAGCGCGGCCGCCTCGACGGCGACGGTGCGCGCAACGACAACTTCCGCGCCAGG
CGCTACATCGCCAAGTACACCATCAACCCGGCGATCACCCACGGCATCAGCCATGAAGTGGGCTCCGTCGAAGCCGGCAA
GTGGGCCGACCTGGTGCTCTGGCGCCCGGCCTTCTTCGGCGTCAAGCCGAGCCTGATCCTCAAGGGCGGGGCCATCGCCG
CCAGCCTGATGGGCGACATCAACGGCTCGATCCCCACGCCGCAGCCGGTGCACTACCGACCGATGTTCGCCAGCTACGCC
GGCAGCCGTCACGCGACTAGCCTGACCTTCGTCAGCCAGGCCGCCTTCGCCGCCGGCGTACCGCAGCAGCTCGGCCTGCG
CAAGGCCATCGGCGTGGTCAGCGGCTGTCGCGGTGTGCAGAAGACCGACCTGATCCACAACGGCTACCTGCCGACCATCG
AGGTCGACGCACAGAACTACCAGGTACGCGCCGACGGCCAGTTGCTCTGGTGCGAACCGGCGGACGTGCTGCCGATGGCG
CAGCGCTATTTCCTGTTCTGA

Protein sequence :
MKISRQAYADMFGPTVGDRVRLADTDLWIEVERDFTVYGEEVKFGGGKVIRDGMGQSQLGAAQVVDTVITNALILDHWGV
VKADVGLKDGRIQAIGKAGNPDIQPGVNIAIGAGTEVIAGEGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGP
AAGTNATTCTSGPWHMARMLQAADAFPMNIGFTGKGNASLPLPLEEQVLAGAIGLKLHEDWGSTPAAIDNCLEVAERHDI
QVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPTRPFTRNTIDEHLDMLMVCHH
LDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRTWQTADKMKRQRGRLDGDGARNDNFRAR
RYIAKYTINPAITHGISHEVGSVEAGKWADLVLWRPAFFGVKPSLILKGGAIAASLMGDINGSIPTPQPVHYRPMFASYA
GSRHATSLTFVSQAAFAAGVPQQLGLRKAIGVVSGCRGVQKTDLIHNGYLPTIEVDAQNYQVRADGQLLWCEPADVLPMA
QRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 0.0 73
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 0.0 73
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-159 61
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-159 61
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-159 61
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-159 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_006485131.1 urease subunit alpha VFG0270 Protein 3e-156 62