Gene Information

Name : PADK2_17395 (PADK2_17395)
Accession : YP_006483460.1
Strain : Pseudomonas aeruginosa DK2
Genome accession: NC_018080
Putative virulence/resistance : Virulence
Product : ClpA/B-type protease
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3757099 - 3759726 bp
Length : 2628 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGATCAACGTAGACCTGCAACAACTGATTCAGGCGCTGGATGCCGACACCCGGCGCGACCTCGAAGGCTCGGCCGAGCG
CTGCGTAGCCCGTGGCGGCAGCAAGGTACTGGTGGAGGACCTGTTGCTGGGCCTGCTGGAGCGTCCCCAGGGACTGCTGG
CGCGCGCCCTGCAGGATGCCGCGGTGGACGCCGGCGAACTCAACGCCGCGTTGCAAGCGCGGGGCGAGCATAGTGCCTCG
CGCAATCCGGTGTTCGCGCCCGAGCTGGTGCAGTGGCTGCAGGATGCGCTGTTGCTGGCCAACCTCGAACTGGGCCGTAG
CCAGATCGACCAGGCGGCATTGATCCTGGCCCTGCTACGCAACCCGTTGCGCTATGCCGGCAGCCGCTACCAGCCGCTGC
TGGCGCGGCTCGACATCGAGCGGTTGAAGGATTTCGCGCTCTCGCAGCCGCTGGAGGGCGCGCCCAGCGGCAAGCCGGGC
GGCGGCGAGTCCCTGTTGCAGCGTTTCACCCACAACCTTACCCAGCAGGCGCGCGACGGCAAGCTCGATCCGGTGCTCTG
TCGCGACGGGGCTATTCGCCAGATGGTCGACATCCTGGCCCGTCGGCGGAAAAACAACCCCATCGTGGTCGGCGAGGCCG
GCGTCGGCAAGACCGCCATCGTCGAAGGCCTGGCCTCGCGGATCGCCGCAGGGGAAGTGCCGCCGGCGCTGAGGGACGTC
GAGCTGTTGTCCCTCGACATGGGCCTGTTGCAGGCCGGTGCCAGCGTGAAGGGCGAGTTCGAGCGGCGCCTGAAAGGCGT
CATCGACGAAGTGAAGGCAGCGCTCAGGCCGACCATCCTGTTCATCGACGAGGCCCATACGCTGATCGGCGCGGGCGGTC
AGGCCGGCGGCTCGGATGCCGCCAACCTGCTCAAGCCGGCCCTGGCACGTGGCGAGTTGCGCACCATCGCGGCGACGACC
TGGGCCGAATACAAGAAGTATTTCGAGAAGGACCCGGCGCTGGCCCGGCGCTTCCAGCCCGTGCAGTTGCATGAGCCGAG
CGTTGCCGAGGCGGTGACGATCCTGCGTGGCCTGGCCCGGGTTTACGAGGAAAGCCACGGTATCTACCTGCGCGACGACG
CGGTGGTGGCCGCCGCCGAACTGTCCGCCCGCTACCTGGCGGGTCGCCAGTTGCCGGACAAGGCCGTCGACGTCCTCGAC
ACCGCCTGTGCCCGGGTGCGCATCAGCCTGGCGGCGGCGCCGGAGAGTCTCGAGCGCCTGCGCGGCGAGCTGGCCGAAGG
CGAGCGCCAGCGCCAGGCCCTGCGCCGCGATGCCGAGGCAGGCCTGCCGATCGACCACGATGCCCTGCAGGCGCTGGAGG
AGCGCCTGGCCCAGGTGGAAAGCGAGCGGCACGTACAGGAGGACCAGTGGAGCCGCCAGCGCGAACTCGCCGAGCGCCTG
CTCGCCCTGCGCCAGCAATTGGCCAGGGCCCGCGAGGCGAACCGGGAAGAGCAGGGCGGCGAGGCGGACGCGGAGACTTT
CCCGGCCGACGAGCATGGCGGTGTCGAAGCCCTGGAAAAGGCCCTTCACGAAACCCGCCAGGCGCTCGCCGATGCCCAGG
CCCAGGGGCGGCTGGTCAGCTTCGAGGTCTGCCCGCGCCTGGTTGCCGAGGTGATCGGCGCCTGGACCGGCGTACCGGTG
GAACAACTGGCGCGGGAACACAACGCCAAGGTGATGGGGTTCGCTGACGACCTGCGGGCGCGGATCCGTGGCCAGGAACA
GGCGGTCAGCGCCCTGGACCGCGCGATGCGCGCCACCGCGGCTGGGCTGAACAAGCCCGATGCGCCGGTCGGCGTGTTCC
TGCTGGTGGGCCCGAGCGGGGTGGGCAAGACCGAGACCGCGCTGGCGCTGGCCGACCTGCTGTATGGCGGCGAGCGTTTC
ATCACCACCATCAACATGTCCGAGTTCCAGGAGAAGCACACCGTCTCGCGCCTGATCGGCGCGCCGCCCGGCTATGTCGG
CTATGGCGAGGGTGGCATGCTCACCGAGGCGGTACGCCAGAAGCCCTATTCGGTGATATTGCTGGACGAGGTGGAGAAGG
CCGATCCGGACGTGCTCAACCTGTTCTACCAGATCTTCGACAAGGGCGTGGCCAACGATGGCGAAGGGCGCGAGATCGAT
TTCCGCAATACCTTGATCCTGATGACCTCCAACCTCGCCAGCGAGCACATCGCCGCGCTTTGCCAGGACGGCGCGCGGCC
TTCCGCCGAACTCCTGGAGGAAACCATCCGGCCGGCGCTCAGCCGGCATTTCAAGCCGGCGCTGCTGGCGCGCATGCGCG
TGGTGCCTTACTACCCGGTGGGCGGCCCGGTACTGCGCGAGCTGATCGAGATCAAGCTGCAACGCCTCGGCGAGCGCCTG
GCGCGCCGTCAACTGGCTTTCGACTACAGCCAGGCGCTGGTGGGCCACCTGGCCGAGCGTTGCACCCAGAGCGACAGCGG
CGCACGGTTGATCGACCACCTGCTGGACACGCACCTGCTGCCGCTGGTGGCCGACCGTTTGCTGGAAGCGATGGCGCGCG
ACGAGCGTCTCGAGCGGGTCCATGCGACGCTGGGCGAGCACGGCCGCGTGCTCTGCGAGTTCGCCTGA

Protein sequence :
MINVDLQQLIQALDADTRRDLEGSAERCVARGGSKVLVEDLLLGLLERPQGLLARALQDAAVDAGELNAALQARGEHSAS
RNPVFAPELVQWLQDALLLANLELGRSQIDQAALILALLRNPLRYAGSRYQPLLARLDIERLKDFALSQPLEGAPSGKPG
GGESLLQRFTHNLTQQARDGKLDPVLCRDGAIRQMVDILARRRKNNPIVVGEAGVGKTAIVEGLASRIAAGEVPPALRDV
ELLSLDMGLLQAGASVKGEFERRLKGVIDEVKAALRPTILFIDEAHTLIGAGGQAGGSDAANLLKPALARGELRTIAATT
WAEYKKYFEKDPALARRFQPVQLHEPSVAEAVTILRGLARVYEESHGIYLRDDAVVAAAELSARYLAGRQLPDKAVDVLD
TACARVRISLAAAPESLERLRGELAEGERQRQALRRDAEAGLPIDHDALQALEERLAQVESERHVQEDQWSRQRELAERL
LALRQQLARAREANREEQGGEADAETFPADEHGGVEALEKALHETRQALADAQAQGRLVSFEVCPRLVAEVIGAWTGVPV
EQLAREHNAKVMGFADDLRARIRGQEQAVSALDRAMRATAAGLNKPDAPVGVFLLVGPSGVGKTETALALADLLYGGERF
ITTINMSEFQEKHTVSRLIGAPPGYVGYGEGGMLTEAVRQKPYSVILLDEVEKADPDVLNLFYQIFDKGVANDGEGREID
FRNTLILMTSNLASEHIAALCQDGARPSAELLEETIRPALSRHFKPALLARMRVVPYYPVGGPVLRELIEIKLQRLGERL
ARRQLAFDYSQALVGHLAERCTQSDSGARLIDHLLDTHLLPLVADRLLEAMARDERLERVHATLGEHGRVLCEFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-145 46
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-145 46
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-122 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PADK2_17395 YP_006483460.1 ClpA/B-type protease VFG2076 Protein 3e-148 51
PADK2_17395 YP_006483460.1 ClpA/B-type protease VFG2084 Protein 1e-143 48