Gene Information

Name : PADK2_12250 (PADK2_12250)
Accession : YP_006482435.1
Strain : Pseudomonas aeruginosa DK2
Genome accession: NC_018080
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2585707 - 2587737 bp
Length : 2031 bp
Strand : -
Note : COG0550 Topoisomerase IA

DNA sequence :
ATGCGGCTGTTCTTGTGCGAGAAGCCCTCCCAGGGCAAAGACATTGGCCGGATTCTCGGCGCCACGCAGCGCGGTGAAGG
CTGCCTCAACGGTTCCGGCGTCACGGTCACCTGGTGCATCGGCCATCTCGTGGAGGCGGCGCCGCCCGAGGCCTACGACG
AGCAGCTCAAACGATGGTCCGTTGAGCAGTTGCCCATCATTCCCCAGCACTGGCGGGTCGAGGTCAAACCGAAGACCGCC
ACGCAATTCAAGGTCGTCAAGGCGCTCTTGGCGAAGGCGACTCACCTGGTTATCGCCACCGATGCCGACCGCGAGGGCGA
ATTGATCGCCCGCGAGATCGTGGAGCTTTGCGGCTACCGCGGCCCCATCGAACGCCTGTGGCTGTCGGCGCTCAACGATG
CGTCCATTCGGGCGGCACTGGGCAAGCTGCGGCCTTCGGCCGAGACGCTTTCGATGTACCACTCGGCGCTGGCGCGCTCC
CGTGCGGATTGGCTCGTGGGCATGAACCTGAGCCGGCTGTTCACGGTGCTGGGGCGACAGGCGGGTTACGACGGCGTGCT
GTCGGTCGGCCGCGTACAGACCCCGACGCTCAAGCTCGTTGTGGACCGCGACCGCGAGATCGCGCGCTTCGTGTCCGTAC
CATACTGGGCCATCGCCGTGTCCCTGTTCGCAGGCGGTTCGACTTTCGCCGCGCAATGGGTTCCACCCGATGCGTGCACC
GACGACGCAGGCCGCTGCCTGCGGCAGCCGGTCGCACAGCAGACCATGCAGCAGATCCGCGCTGCGGGCAGTGCCCACGT
CGTGTCGGTGGAGACTGAGCGTGTCCGCGAAGGCCCGCCGCTGCCGTTCGACCTGGGCACCTTGCAGGAAGTGTGTTCCA
AGCAGCTTGGGCTGGACGTGCAGGAAACCTTGGAGATTGCCCAAGCCCTGTACGAGACGCACAAGGCCACGACGTACCCC
CGCTCGGACTCCGGCTACCTGCCCGAGAGCATGTTTGCCGAAGTGCCCACCGTTCTCGACAGCCTGCTCAAGACCGATCC
CTCGCTGCGCTCGATCATGGGCCAGCTCGACCGCTCGCAGCGCTCGCGCGCCTGGAACGATGGCAAGGTCACGGCGCACC
ACGGCATCATCCCGACGCTCGAACCGGCGAAGCTCTCCGCCATGAGCGAGAAGGAACTGGCCGTGTACAGGCTCATCCGG
TCGCATTACCTGGCGCAGTTCCTCCCTCACCACGAGTTCGACCGCACTGTGGCCAAGTTTTCGTGCGGGGGGCAGAACCT
GGCGGCCACGGGCAAGCAGGTTGTCATCCCGGGTTGGCGCCAGGTGCTCGCCGAGCCGCAGGCCGAAGACGGTGATGGCG
AGGGCGATACTGCGGTCCGCGCCCAGGTGCTGCCCGCGCTGCCGAAACTGTATGAGGGCCTGGCATGCCAGGTGGCCGAC
GTCGATCTCAAGGCACTCAAGACGCTGCCGCCCAAACCGTACACGCAAGGCGAGTTGGTCAAGTCCATGAAAGGCGTCGC
CAAGCTGGTGTCCGATCCCCGCCTGAAGCAGAAGCTCAAGGATACGGTTGGCATCGGCACCGAAGCGACGCGGGCCAACA
TCATCGGCGGCCTGATCGCTCGCGGCTACCTCGTGAAGAAGGGGCGCGCCATCCGCGCCTCGGATGCGGCTTTCACTTTG
ATCGATGCCGTGCCTGCGGCGATTGCCGACCCTGGCACCACCGCCGTCTGGGAACAGGCGCTCGACATGATCGAGGCCGG
ACAGCTCACCCTGGACGTGTTCATCGGCAAGCAGGCCGCGTGGATTTCGCAGTTGATTGCGCAGTACGGCAGCGCCTCCC
TGTCCATCAAGGTTCCCCAAGGGCCGGCATGCCCGCAGTGCGGCGCACCCACGCGCCAGCGCAGCGGCAAGAGCGGCCCG
TTCTGGTCGTGCAGCCGCTACCCGGACTGCAAAGGCACGCTGCCAGTCGAATCCGGCAGCTCCAAGCGCGGCGCCTCGCG
CCCGCGCCGTAGCGGCCGCAAAGGCTCCTGA

Protein sequence :
MRLFLCEKPSQGKDIGRILGATQRGEGCLNGSGVTVTWCIGHLVEAAPPEAYDEQLKRWSVEQLPIIPQHWRVEVKPKTA
TQFKVVKALLAKATHLVIATDADREGELIAREIVELCGYRGPIERLWLSALNDASIRAALGKLRPSAETLSMYHSALARS
RADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIARFVSVPYWAIAVSLFAGGSTFAAQWVPPDACT
DDAGRCLRQPVAQQTMQQIRAAGSAHVVSVETERVREGPPLPFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYP
RSDSGYLPESMFAEVPTVLDSLLKTDPSLRSIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPAKLSAMSEKELAVYRLIR
SHYLAQFLPHHEFDRTVAKFSCGGQNLAATGKQVVIPGWRQVLAEPQAEDGDGEGDTAVRAQVLPALPKLYEGLACQVAD
VDLKALKTLPPKPYTQGELVKSMKGVAKLVSDPRLKQKLKDTVGIGTEATRANIIGGLIARGYLVKKGRAIRASDAAFTL
IDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIAQYGSASLSIKVPQGPACPQCGAPTRQRSGKSGP
FWSCSRYPDCKGTLPVESGSSKRGASRPRRSGRKGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 100
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 75
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 63
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 9e-172 50
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 9e-172 50
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 7e-172 50
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-167 49
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 3e-171 49
topB AAW83109.1 TopB Not tested GGI Protein 2e-123 41