Gene Information

Name : ureC (A3UG_19475)
Accession : YP_006479307.1
Strain : Enterobacter cloacae SDM
Genome accession: NC_018079
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 4199517 - 4201220 bp
Length : 1704 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGGCTGAAATTTCGCGCCAGGCTTATGCCGATATGTTCGGCCCCACCACCGGCGATAAAGTACGATTAGCCGACAGTGA
GCTGTGGATCGAAGTGGAAGACGATCTCACCGTCTACGGCGAAGAGGTTAAATTTGGCGGCGGGAAAGTGATCCGTGACG
GCATGGGCCAGGGGCAGATGACCGCGCAAGACTGCGTGGATCTGGTGCTGACTAACGCGTTGATTGTCGATCACTGGGGG
ATCGTGAAAGCGGATATCGGCGTGAAGAACGGGCGGATCTTCGCCGTCGGCAAAGCCGGTAACCCTGACATTCAGCCTGG
CGTAACGATCCCGATCGGTGCCGCCACAGAAGTGATCGCCGCTGAAGGGAAGATCGTCACCGCTGGCGGGATCGACACCC
ACATCCACTGGATCTGCCCGCAACAGGCCGAAGAGGCGCTGGTTTCCGGCGTCACAACGATGATCGGCGGCGGTACGGGA
CCTGCGGCAGGGACCAACGCCACCACCTGCACGCCGGGACCGTGGTATATCGCCCGTATGCTGCAGGCTGCCGATACCCT
GCCGGTGAATATCGGCCTGCTCGGCAAAGGTAACGGTTCAAACCCGGATGCCCTGCGCGAGCAGATAGTCGCCGGTGCCA
TCGGACTTAAGATCCACGAAGACTGGGGCGCGACGCCCGCGGCCATCAACTGCTCGCTGGAGGTGGCGGAAGAGATGGAC
ATTCAGGTGGCGCTGCACAGCGACACGCTGAACGAATCCGGTTTCGTCGAAGACACGCTGGCCGCCATTGGCGGGCGCAC
CATCCATACTTTCCACACTGAAGGAGCAGGCGGTGGCCACGCGCCGGATATTATTACCGCCTGCGCACACCCCAATATTC
TGCCCTCCTCCACCAACCCGACGCTGCCCTATACGGTCAATACCATCGATGAACATCTCGACATGCTGATGGTCTGCCAC
CACCTCGACCCGGATATCGCCGAGGACGTAGCCTTTGCCGAATCGCGTATTCGCCGGGAAACCATCGCCGCGGAGGATGT
GCTGCACGATATCGGCGCATTCTCGCTGACCTCTTCTGATTCCCAGGCGATGGGCCGCGTGGGCGAAGTGATTATCCGCA
CCTGGCAGGTGGCGCACCGCATGAAGGTGCAGCGCGGCGCACTGCCGGAAGAGACCGGCGATAACGACAACTTTCGCGTG
AAGCGCTACGTCGCCAAATACACCATTAACCCGGCACTTACCCACGGTATCGCCCACGAAGTGGGCTCCATCGAGGCGGG
CAAGCTGGCGGATTTAGTGGTCTGGTCCCCGGCGTTCTTTGGCGTGAAACCCGCCACCATCGTCAAGGGCGGGATGATCG
CCTGCGCGCCGATGGGCGATATCAACGCCTCGATTCCCACGCCGCAACCGGTCCACTACCGCCCGATGTTTGGTGCGCTG
GGTGCCGCACGCCACGCCACCCGGCTGACGTTTGTCTCGCAGGCTGCTGACGCGCTGGGAATGGCACAACAGCTCAACCT
GCAGAGCGCCACAGCGGTGGTCAAAGGCTGCCGGACGGTGAAAAAAGCCGACATGATCCACAACGGCCTGCAGCCAAATA
TCACCGTCGATTCGCAAACCTATGAAGTGCGCGTCGACGGCGAACTGATAACCAGCGAACCGGCTGACGTTCTGCCGATG
GCGCAACGCTATTTCCTGTTTTGA

Protein sequence :
MAEISRQAYADMFGPTTGDKVRLADSELWIEVEDDLTVYGEEVKFGGGKVIRDGMGQGQMTAQDCVDLVLTNALIVDHWG
IVKADIGVKNGRIFAVGKAGNPDIQPGVTIPIGAATEVIAAEGKIVTAGGIDTHIHWICPQQAEEALVSGVTTMIGGGTG
PAAGTNATTCTPGPWYIARMLQAADTLPVNIGLLGKGNGSNPDALREQIVAGAIGLKIHEDWGATPAAINCSLEVAEEMD
IQVALHSDTLNESGFVEDTLAAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTLPYTVNTIDEHLDMLMVCH
HLDPDIAEDVAFAESRIRRETIAAEDVLHDIGAFSLTSSDSQAMGRVGEVIIRTWQVAHRMKVQRGALPEETGDNDNFRV
KRYVAKYTINPALTHGIAHEVGSIEAGKLADLVVWSPAFFGVKPATIVKGGMIACAPMGDINASIPTPQPVHYRPMFGAL
GAARHATRLTFVSQAADALGMAQQLNLQSATAVVKGCRTVKKADMIHNGLQPNITVDSQTYEVRVDGELITSEPADVLPM
AQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 0.0 88
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 0.0 88
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-163 63
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-163 63
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-163 63
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-163 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_006479307.1 urease subunit alpha VFG0270 Protein 8e-156 63