Gene Information

Name : guaA (A3UG_16805)
Accession : YP_006478787.1
Strain : Enterobacter cloacae SDM
Genome accession: NC_018079
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 3624085 - 3625662 bp
Length : 1578 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGACGGAAAACATTCATAAACATCGCATTCTCATCCTGGACTTTGGTTCTCAGTACACTCAGCTGGTGGCGCGTCGCGT
GCGTGAACTGGGCGTTTACTGTGAACTGTGGGCGTGGGATGTCACGGAAGCACAGATTCGCGAATTCAATCCAAGCGGCA
TCATCCTGTCCGGCGGCCCGGAAAGCACCACCGAAGATAACAGCCCGCGCGCACCACAGTACGTGTTCGAAGCGGGTGTA
CCGGTGTTCGGCGTTTGCTACGGTATGCAGACGATGGCAATGCAGCTGGGCGGCCACGTAGAAGGCTCTAACGAGCGTGA
GTTTGGCTACGCACAGGTCGAAGTGGTGAACGACAGCGCGCTGGTGCGCGGTATCGAAGACTCCCTGACTGCAGACGGCA
AACCGCTGCTGGACGTGTGGATGAGCCACGGCGATAAAGTGACCGCTATCCCGTCCGACTTCGTGACCGTTGCCAGCACC
GAAAGCTGCCCGTTCGCGATTATGGCGAACGAAGAGAAACGCTTCTACGGCGTGCAGTTCCACCCGGAAGTGACTCACAC
CCGTCAGGGTATGCGCATGCTGGAGCGCTTCGTGCGCGATATCTGCCAGTGTGAAGCCCTGTGGACCCCGGCTAAAATCA
TCGACGACGCCGTTGAGCGTATCCGTCAGCAGGTTGGCGATGACAAAGTGATCCTCGGCCTGTCCGGTGGCGTGGACTCC
TCCGTAACCGCGATGCTGCTGCACCGCGCTATCGGTAAAAACCTGACCTGCGTATTCGTGGACAACGGTCTGCTGCGTCT
GAATGAAGCCCAGCAGGTCATGGACATGTTTGGTGACCACTTCGGTCTGAACATCGTTCACGTGGAAGGCGAACAGCGCT
TCCTGGACGCGCTGGCCGGTGTCAACGATCCGGAAGCCAAACGTAAGATCATTGGCCGCGTCTTCGTGGAAGTGTTCGAC
GAAGAAGCGCTGAAGCTGGAAGACGTGAAGTGGCTGGCACAGGGCACAATCTACCCTGACGTGATCGAATCTGCGGCCTC
CGCCACCGGTAAAGCACACGTCATCAAATCTCACCACAACGTGGGCGGCCTGCCGAAAGAGATGAAGATGGGTCTGGTTG
AACCGCTGCGTGAGCTGTTCAAAGACGAAGTGCGTAAGATCGGTCTGGAACTGGGTCTGCCGTACGACATGCTCTACCGT
CACCCGTTCCCGGGTCCGGGTCTGGGCGTGCGCGTGCTGGGCGAAGTGAAGAAAGAGTACTGCGACCTGCTGCGTCGCGC
GGATGCTATCTTCATCGAAGAGCTGCACAAAGCTGACCTGTACAACAAAGTGAGCCAGGCGTTCACCGTGTTCCTGCCGG
TTCGCTCCGTCGGCGTAATGGGCGATGGCCGTAAGTACGACTGGGTTGTTTCCCTGCGTGCGGTGGAAACCATCGACTTC
ATGACCGCGCACTGGGCGCACCTGCCGTATGACTTCTTAGGCCGTGTGTCTAACCGCATCATCAACGAAGTGAACGGTAT
TTCCCGCGTGGTGTATGACATCAGCGGTAAGCCACCGGCTACGATTGAGTGGGAATAA

Protein sequence :
MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIREFNPSGIILSGGPESTTEDNSPRAPQYVFEAGV
PVFGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVVNDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVERIRQQVGDDKVILGLSGGVDS
SVTAMLLHRAIGKNLTCVFVDNGLLRLNEAQQVMDMFGDHFGLNIVHVEGEQRFLDALAGVNDPEAKRKIIGRVFVEVFD
EEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLRELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-128 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-128 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-128 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-112 48