Gene Information

Name : A3UG_14945 (A3UG_14945)
Accession : YP_006478417.1
Strain : Enterobacter cloacae SDM
Genome accession: NC_018079
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3195035 - 3198097 bp
Length : 3063 bp
Strand : +
Note : COG0841 Cation/multidrug efflux pump

DNA sequence :
ATGGATATCTCTCGCCAGTTTATCAATAACCCCATTCGCGTCTGGCTGACGATCCTGCTGCTGGGCGTGGGCGGCATTTT
CGCCCTGCTGAACATTGGCAGGCTGGAAGATCCCGCCTTTACCATAAAAACCGCGGTGGTGATCACCCACTATCCCGGCG
CCTCCGCTCAGCAGGTTGAAGAGGAGGTCACGCTACCGCTAGAGAATGCCCTTCAGCAGCTGCCCTATCTGGACAACGTG
AGCTCCATCTCTTCCAACGGCCTGTCGCAAATCACCGTGAACATCGCCTCACGTTATCATTCGAACGAACTGCCGCAGAT
CTGGGACGAACTGCGCCGTCGCGTGGGCGATGCTTCGCGCCAGTTCCCGCCCGGCGTCGTGACGCCCTTCGTGAATGATG
ATTTTGGCGATGTGTTCGGCTTTTTCTTCGCGATTTCCGGGGATGAATTCAGCAATCCTGAACTGGTGAGATATGCCGAG
CAGCTGCGGCGCGAACTGATTCTGGTCCCCGGCGTCGGTAAGGTTGCCATCGGCGGGGCCATCAGCCAGCAGGTCAATAT
CGATATATCCCTGACCAAAATGGCGGCCCGCGGCATCACGCTGAACCAGCTTTCCGCCCTGCTCAGCAGGCTTAACGTCG
TTTCCAGCGCCGGAGAAATCACCTCGGGAACGGAATCCATTCGCCTGCATCCAACCGGTGAGTTCGAAAATCTTGATGAA
CTGGCGGATCTCATCATTACCCCTTCCGGCACCGGGGCGGCGACGCGTCTGCGGGATATCGCCACGCTGTCGCGCGGGCT
GAACGAATCGCCCGCCAGTATCTATCATGCCAACGGCAGGAAAGCCGTTACCATGGGCGTCTCGTTTATTCCCGGCGTGA
ACGTGATCGACGTGGGACACGCGCTGGAGGCAAAGCTCAACCAGATGTCAGCGGAAAAACCGGCAGGGATACACATCGAC
CTGTTCTACGATCAGGCCGCCGAAGTGGGGCACTCTGTAAATGGTTTTATCATTAACTTCCTGATGGCGCTGGCGATTGT
TATCGGCGTGCTGCTGATCTTTATGGGTGTCCGCAGCGGGATCATCATCGCGTTTTCCCTCGCACTTAACGTGCTGGGCA
CGCTGCTCATCATGTATCTGTGGGGTATTGAGCTGCAGCGCATCTCGCTCGGCGCGCTGATTATCGCCCTCAGTATGCTG
GTGGATAATGCCATCGTGATCGTTGAAGGGGTGCTGATTGCGCGTCAGCAAGGTTCCCCGCTGTTAACCGCCATTAACTA
CATCATCCGTCGTTCCGCCCTGCCGCTGCTGGGGGCGACGGTGATCGCCATCCTCGCGTTTGCGCCTATCGGGCTGTCCC
AGGACTCTACCGGGGAATACTGTAAATCCCTGTTCCAGGTACTGCTGATTTCCCTGATGCTGAGCTGGTTCTCGGCGCTC
ACCATCACGCCGGTGCTGATCACATGGTGGTTGTTTAAAAATGACAGCGCGCCGGAAAAAAGTGACGAGGCAGACCCTTA
CGACAAACGCCTCTATCGACTTTACCGGCGCCTGCTTAACGCGCTGCTGCACCGGAAAGCGCCGACGCTCATCGTGATGG
CTGCGCTGCTGGCAGCGTCAGTCTGGGGTTTTGGTGCCGTGCGGCAAAACTTCTTCCCGTCGTCAAATACGCCCATTTTC
TTTGTCGACCTCTGGCTACCCTACGGCACCGATATCAAATGGACCGAGAAGATGACCGGCGATATCGAGAAAACCATCAA
CGGCCAGCCCGGCGTGGAAACCACCGTCTCAACCATCGGTCAGGGCAGCATGCGGTTTATTCTGACCTACAGCGGACAGC
GGCAGTACAGCAACTATGCCCAAATCATGGTAAGAATGGATGACCAGCGCAACATCTCCGCATTGACGCGCCACGTCGAT
GAGTACATTGCGCGAAACTATCCGCAGGTAAACGCCAGCACCAAACGCGTGATGTTTGGTCCCTCTGGCGACAGCGCCAT
TGAGGTGCGCATCAAGGGCCCCGATCCTGACAGGTTGCGTCTGATTGCCAGCCAGGTGGACGAGATCCTGGCGCGCGACC
CGGCCACGGCAAGCGTGAGAAACGACTGGCAAAACCGCAGCAAGGTGCTCCGTCCGCAGTACGTCGCCGCACTGGGGCGC
GAGCTTGGCGTGGATAAGCAGGACGTCGACAACGCGCTGGAGATGAATTTCTCCGGCAGCCGGGCGGGATTATATCGGGA
AGGCAGTGACCTGCTTCCGGTCGTGGTACGCCCGCCGGAACGCGAACGGCTGGACGCGAATCACCTGAACAACGTGCTGG
TATGGAGTCAGACCCGGCAGCAGTATATCCCGCTGAGTAATGTCGTCAGCCGCTTCTCGCTGGAATGGGAAGATCCGCTG
ATTTTGCGACGCGACCGCTCGCGGGTGCTGACCGTTCAGACCGACCCCGATCCGCTTAGCCAGCAAACGTCAGGCGATAT
TCTCGCCCGGGTGAAGCCGCGCATTGACGCCCTCGCCCTGCCCCACGGATACAGCATTGAGTGGGGAGGCGATGCGGAAA
ACTCCAGCGAAGCACAACAGGGGATCTTTACCACGCTGCCGATCGGGTTCCTGGTGATGTTTGTCATCACCGTTTTGATG
TTCAGCTCGGTGAAAAACGCCGTTGCCATCTGGCTGACCGTGCCGCTGGCGCTGATTGGCGTCACGCCGGGATTCTTAAT
CACTGGTATTCCGTTCGGCTTTATGGCGCTGATTGGCCTGCTGAGCCTGAGCGGGATGCTGATCCGCAACGGCATTGTGC
TGGTGGAAGAGATCGAGCAGCAGAAGGCGCATAAAGGTCAGCACGAGGCGATTGTTTATGCTGCCACCTCGCGCCTGCGC
CCCATTCTGCTCACCGCATTTACCACCGTACTGGGCCTGGCACCGCTGCTGCTGGACGTTTTCTTCCAGAGCATGGCCGT
TGTGATTATGTTTGGACTGGGGTTTGCTACAATCCTGACGCTGCTGGTACTTCCCGTAATTTACGCGTGCTTCCATCGTA
AGGACAAAGCGGAACAACAATGA

Protein sequence :
MDISRQFINNPIRVWLTILLLGVGGIFALLNIGRLEDPAFTIKTAVVITHYPGASAQQVEEEVTLPLENALQQLPYLDNV
SSISSNGLSQITVNIASRYHSNELPQIWDELRRRVGDASRQFPPGVVTPFVNDDFGDVFGFFFAISGDEFSNPELVRYAE
QLRRELILVPGVGKVAIGGAISQQVNIDISLTKMAARGITLNQLSALLSRLNVVSSAGEITSGTESIRLHPTGEFENLDE
LADLIITPSGTGAATRLRDIATLSRGLNESPASIYHANGRKAVTMGVSFIPGVNVIDVGHALEAKLNQMSAEKPAGIHID
LFYDQAAEVGHSVNGFIINFLMALAIVIGVLLIFMGVRSGIIIAFSLALNVLGTLLIMYLWGIELQRISLGALIIALSML
VDNAIVIVEGVLIARQQGSPLLTAINYIIRRSALPLLGATVIAILAFAPIGLSQDSTGEYCKSLFQVLLISLMLSWFSAL
TITPVLITWWLFKNDSAPEKSDEADPYDKRLYRLYRRLLNALLHRKAPTLIVMAALLAASVWGFGAVRQNFFPSSNTPIF
FVDLWLPYGTDIKWTEKMTGDIEKTINGQPGVETTVSTIGQGSMRFILTYSGQRQYSNYAQIMVRMDDQRNISALTRHVD
EYIARNYPQVNASTKRVMFGPSGDSAIEVRIKGPDPDRLRLIASQVDEILARDPATASVRNDWQNRSKVLRPQYVAALGR
ELGVDKQDVDNALEMNFSGSRAGLYREGSDLLPVVVRPPERERLDANHLNNVLVWSQTRQQYIPLSNVVSRFSLEWEDPL
ILRRDRSRVLTVQTDPDPLSQQTSGDILARVKPRIDALALPHGYSIEWGGDAENSSEAQQGIFTTLPIGFLVMFVITVLM
FSSVKNAVAIWLTVPLALIGVTPGFLITGIPFGFMALIGLLSLSGMLIRNGIVLVEEIEQQKAHKGQHEAIVYAATSRLR
PILLTAFTTVLGLAPLLLDVFFQSMAVVIMFGLGFATILTLLVLPVIYACFHRKDKAEQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 6e-170 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A3UG_14945 YP_006478417.1 acriflavin resistance protein BAC0519 Protein 0.0 50
A3UG_14945 YP_006478417.1 acriflavin resistance protein BAC0428 Protein 0.0 50
A3UG_14945 YP_006478417.1 acriflavin resistance protein BAC0526 Protein 0.0 48
A3UG_14945 YP_006478417.1 acriflavin resistance protein BAC0425 Protein 3e-170 41