Gene Information

Name : A3UG_14855 (A3UG_14855)
Accession : YP_006478399.1
Strain : Enterobacter cloacae SDM
Genome accession: NC_018079
Putative virulence/resistance : Virulence
Product : Aerobactin siderophore biosynthesis protein iucA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3175708 - 3177450 bp
Length : 1743 bp
Strand : +
Note : COG4264 Siderophore synthetase component

DNA sequence :
ATGCGTACTCTGCCCCGCTCTGCCGGTACAGACGTTGCGGCCCAGTGTTTTTTAAACGCCCTGTTGCGCGAAACGAAGGA
CTGGCGCTATCTCCCCGCTACCGCTGCGGATGAGCTATCGCAGATCCATATCCCGCTCTCGCAAACCCAGGCCATCCGGG
TTTCAGTACACTATTTCTCCCCAACCCAGCATCATCAGTACCGCTTCCCGGCAACGCTCATCCAGACCGACAGCGACCGT
AGTGACGCCGTCACTTTCCCTCAACTGGTTGATTTAATTCTTGAAAAAACCTCTGTAAAAGGCTCGCTGGATGCCGATAC
GCTGGCGCGCTTTAAGCAGCGCGCCCTCGAAAGCCATGCCCATACCTGGCAGGCGATCGACTTGCGTCACAACTGGGCAA
ACCTGCGCGACACACCGCTGACGTTCGCCGAGGCGGAACAGGCGCTGCTGGTCGGCCACGCATTCCATCCGGCCCCGAAG
TCACACGAGCCGTTTAACGAAGCCGAAGCCCGCCGCTATTTGCCCGATTTTGCCTCCCGTTTCCCGCTGCGCTGGTTTGC
TGTTGAGAGCGAACTGATCGCCGGCGAGAGCCTGAACGTCTCCCTGCGTGAACGTCTGCTGCGCTTCGCAGCCCAGAGCG
CCCCTGAACTGCTCGGTCATTTCACCGACACCCGCTGGCTGCTGCCGATGCACCCGTGGCAGGCGGAGTACCTGCTCGGT
CAGGTCTGGTGCCAGCGACTGGTGGCGAAGGGAGCGCTGCAGGATCTGGGCGAAGCGGGCGCGCAGTGGCTACCGACCAG
CTCCTCCCGCTCGCTGTACAGCGAAACCAACAGCGACATGATTAAGTTTTCCCTGAGCGTGCGCCTGACCAACTCGGTGC
GCACGCTGTCGGTGAAAGAGGTTAAGCGCGGGATGCGTCTGGCGCGTCTGGCGAAGACGGCGCGCTGGCAGGAGCTCCAG
GCGCGCTACCCGACCATGCGCGTGATGCAGGAAGACGGCTGGGCCGGTCTGCGCGACGAAAGCGGCTCCATTCAGGAAGA
GAGCCTGATGGCCCTGCGCGTGAACCTGCTGTTTGATACGCCGGATACGCAAACCAACGTGCTGGTGAGCCTGACGCAGG
CCGCGCCGGACGGCGGTGACAGCCTGCTGGCGGCTGCGGTCCGCCGTCTGAGCCAGCGTCTGGCTCTCCCCCTCGCCCAG
GCCGCGCGCTGCTGGCTGGACGCCTATTGCGACCGCGTTCTCCTTCCGCTGTTCAGCGCCGAAGCCGATTACGGTCTGGT
TCTGCTGGCACATCAGCAAAACATCCTCGTGGAGATGCAGCAGGACTTCCCGGTCGGGCTTATCTACCGTGACTGCCAGG
GCAGCGCCTGGACCGAAGGGGCCGACGCATGGCTGAAAGAGGCAGGTGAAAGCGAGGTGGAAAACCGCTTCGGCGAGAGC
CAGCTGCTGCGCTACTTCCCGTATTACCTGCTGCTAAACTCCACCCTTGCCGTCACTGCCGCCCTCGCCGCCGCAGGTTT
CGACAGCGAAGAGAGCCTGATGTCACGGGTGCGTGACGCGCTGACCAGCCTGCGCCAGACCGCGAAGCAGACCCGCTGTC
TCGACTACGTGCTCGACAGCCCGACGTGGAACTGCAAAGGCAACTTTTTCTGCTACCTGCACGATCGCAACGAAAACACG
ATTGTCGATCCGGCAGTGATCTATTTCGACTTTAGCAACCCGTTTTACAAGGAGAAGGCGTGA

Protein sequence :
MRTLPRSAGTDVAAQCFLNALLRETKDWRYLPATAADELSQIHIPLSQTQAIRVSVHYFSPTQHHQYRFPATLIQTDSDR
SDAVTFPQLVDLILEKTSVKGSLDADTLARFKQRALESHAHTWQAIDLRHNWANLRDTPLTFAEAEQALLVGHAFHPAPK
SHEPFNEAEARRYLPDFASRFPLRWFAVESELIAGESLNVSLRERLLRFAAQSAPELLGHFTDTRWLLPMHPWQAEYLLG
QVWCQRLVAKGALQDLGEAGAQWLPTSSSRSLYSETNSDMIKFSLSVRLTNSVRTLSVKEVKRGMRLARLAKTARWQELQ
ARYPTMRVMQEDGWAGLRDESGSIQEESLMALRVNLLFDTPDTQTNVLVSLTQAAPDGGDSLLAAAVRRLSQRLALPLAQ
AARCWLDAYCDRVLLPLFSAEADYGLVLLAHQQNILVEMQQDFPVGLIYRDCQGSAWTEGADAWLKEAGESEVENRFGES
QLLRYFPYYLLLNSTLAVTAALAAAGFDSEESLMSRVRDALTSLRQTAKQTRCLDYVLDSPTWNCKGNFFCYLHDRNENT
IVDPAVIYFDFSNPFYKEKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucA NP_709454.2 siderophore biosynthesis protein Virulence SHI-2 Protein 3e-166 65
iucA AAD44746.1 IucA Virulence SHI-2 Protein 2e-166 65
iucA NP_839223.1 siderophore biosynthesis protein Virulence SHI-2 Protein 3e-166 65
iucA YP_002414046.1 aerobactin siderophore biosynthesis protein Virulence Not named Protein 1e-166 65
iucA AAK71631.1 IucA Virulence SHI-3 Protein 5e-151 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A3UG_14855 YP_006478399.1 Aerobactin siderophore biosynthesis protein iucA VFG0615 Protein 1e-166 65
A3UG_14855 YP_006478399.1 Aerobactin siderophore biosynthesis protein iucA VFG0940 Protein 4e-167 65
A3UG_14855 YP_006478399.1 Aerobactin siderophore biosynthesis protein iucA VFG1081 Protein 3e-151 62