Gene Information

Name : A3UG_11440 (A3UG_11440)
Accession : YP_006477724.1
Strain : Enterobacter cloacae SDM
Genome accession: NC_018079
Putative virulence/resistance : Virulence
Product : DNA-binding transcriptional activator CusR
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2474351 - 2475034 bp
Length : 684 bp
Strand : +
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
ATGAAAATATTGATTGTTGAAGACGAAATTAAAACCGGTGAGTACCTCAGCAAAGGGCTTACGGAAGCGGGCTTTGTGGT
GGATCGCGCTGACAACGGCCTGACCGGCTACCATCTCGCCATGACCGCCGATTATGACCTGTTGATTCTGGATATCATGC
TTCCCGATGTGAACGGCTGGGATATCATCCGCATGCTCCGCTCTGCCGGAAAGGGAATGCCGGTCCTGTTGCTGTCGGCT
CTCGGCACCATTGAACACCGGGTGAAAGGTCTGGAACTGGGGGCGGATGATTACCTGGTTAAGCCCTTTGCCTTTGCTGA
GCTGCTCGCCCGGGTCAGAACGCTGTTACGACGCGGCAATACGGTGATCGCCGAGAGCCAGTTTACGGTGGCAGATCTGA
GCATCGACCTCGTATCACGAAAGGTAAACCGCGCCGGAAACCGCATTCTGCTCACCAGCAAAGAGTTCAGCCTGCTGGAG
TTTTTTGTTCGCCATCAGGGCGAAGTGCTGCCCCGCTCGCTGATTGCTGCGCAGGTCTGGGACATGAATTTCGACAGCGA
CACCAACGCGATTGACGTTGCGGTGAAGCGGTTACGCGCCAAAATCGACAACGATTATGAACCGAAGCTGATCCAGACGG
TGCGCGGCGTGGGCTATATGCTGGAGGTTCCGGATGCACAGTAA

Protein sequence : 
MKILIVEDEIKTGEYLSKGLTEAGFVVDRADNGLTGYHLAMTADYDLLILDIMLPDVNGWDIIRMLRSAGKGMPVLLLSA
LGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGNTVIAESQFTVADLSIDLVSRKVNRAGNRILLTSKEFSLLE
FFVRHQGEVLPRSLIAAQVWDMNFDSDTNAIDVAVKRLRAKIDNDYEPKLIQTVRGVGYMLEVPDAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 9e-55 53
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 2e-54 52

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR BAC0111 Protein 1e-95 89
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR BAC0347 Protein 2e-91 89
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR BAC0638 Protein 1e-64 62
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR BAC0083 Protein 2e-70 61
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR BAC0197 Protein 7e-66 60
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR BAC0308 Protein 2e-62 59
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR BAC0125 Protein 2e-62 56
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR AE000516.2.gene3505. Protein 3e-27 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR VFG0596 Protein 3e-55 53
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR VFG1390 Protein 2e-43 44
A3UG_11440 YP_006477724.1 DNA-binding transcriptional activator CusR VFG1389 Protein 3e-34 42