Gene Information

Name : A3UG_07145 (A3UG_07145)
Accession : YP_006476872.1
Strain : Enterobacter cloacae SDM
Genome accession: NC_018079
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1562472 - 1563761 bp
Length : 1290 bp
Strand : -
Note : COG1055 Na+/H+ antiporter NhaD and related arsenite permeases

DNA sequence :
ATGTTTCTGGCAGGGGCAATTTTTCTGTTTACGCTGGTACTGGTCATCTGGCAGCCCAAAGGGCTCAGTATCGGCTGGAG
CGCGACAATTGGCGCCGGGCTGGCGCTGGCCAGCGGCGTCATCCACCTTAACGATATTCCGGTGGTATGGAATATCGTCT
GGAATGCCACGGCGACGTTTATCGCCGTTATTATCATCAGCCTGCTGCTGGATGAGTCCGGCTTTTTCGAGTGGGCGGCG
CTGCATGTCGCCCGCTGGGGAAACGGTCGGGGGCGTTTGCTGTTTACTTATATCGTGCTGCTGGGTGCGGCCGTCGCGGC
GCTGTTTGCCAATGACGGTGCAGCGTTGATCCTGACACCTATCGTCATCGCCATGCTGCTGGCGCTGGGGTTCAGCAAGC
AGGCCACACTGGCGTTTGTGATGGCGGCAGGTTTTATCGCCGATACCGCCAGCCTGCCGCTGATTGTGTCGAACCTGGTC
AACATTGTGTCGGCAGACTTCTTTAAACTGGGCTTCGGCGAATACGCCTCGGTGATGATCCCGGTTGATATCGCCGCGAT
TGCTGCCACGCTGGTGATGCTGCATCTGTTCTTTCGCAAGGAAATTCCGCCGGAATATGATCTTGCGAAACTCCGTGAGC
CTGCCCGGGCCATTCACGACCTCCCGACGTTCAGAACGGGCTGGATAGTGCTACTGCTTCTTCTCGTCGGCTTCTTTGTG
CTTGAGCCTCTCGGCATTCCGGTCAGCGCCATTGCAACAGCTGGCGCGCTGATTTTATTCGCCGTTGCAAAACGCGGACA
CGCGATTAATACCGGAAAAGTGCTGCGCGGCGCACCGTGGCAGATCGTCATCTTCTCACTGGGGATGTATCTGGTGGTCT
ACGGTTTGCGTAACGCCGGGTTAACCGAATACCTTTCAGGCGTGCTGAATGCTCTCTCCACCCACGGTTTATGGGTGACT
ACCCTGGGAACCGGGTTCATCACCGCTTTCCTGTCATCCATAATGAACAATATGCCCACGGTGCTGATTGGCGCGCTCTC
TATTGATGGCAGTACGGCAACAGGATTGATCAAGGAAGCGATGATTTATGCCAACGTGATTGGCTGCGATCTGGGGCCGA
AAATCACGCCTATCGGTAGTCTCGCCACCCTGCTCTGGCTCCACGTGCTGGCGCAGAAAAACATGACCATTACCTGGGGT
TACTATTTCCGGACGGGCATCATCATGACGCTGCCGGTTCTGTTTGTGACGCTCGCCGTGCTGGCGTTACGTCTCTCCTT
CACACTGTAA

Protein sequence :
MFLAGAIFLFTLVLVIWQPKGLSIGWSATIGAGLALASGVIHLNDIPVVWNIVWNATATFIAVIIISLLLDESGFFEWAA
LHVARWGNGRGRLLFTYIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKQATLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFKLGFGEYASVMIPVDIAAIAATLVMLHLFFRKEIPPEYDLAKLREPARAIHDLPTFRTGWIVLLLLLVGFFV
LEPLGIPVSAIATAGALILFAVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNALSTHGLWVT
TLGTGFITAFLSSIMNNMPTVLIGALSIDGSTATGLIKEAMIYANVIGCDLGPKITPIGSLATLLWLHVLAQKNMTITWG
YYFRTGIIMTLPVLFVTLAVLALRLSFTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 2e-160 89
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-100 61
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 4e-98 60
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 4e-102 60

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A3UG_07145 YP_006476872.1 arsenical pump membrane protein BAC0576 Protein 2e-161 90
A3UG_07145 YP_006476872.1 arsenical pump membrane protein BAC0578 Protein 8e-163 90
A3UG_07145 YP_006476872.1 arsenical pump membrane protein BAC0031 Protein 2e-161 89
A3UG_07145 YP_006476872.1 arsenical pump membrane protein BAC0577 Protein 4e-154 87
A3UG_07145 YP_006476872.1 arsenical pump membrane protein BAC0574 Protein 1e-100 61
A3UG_07145 YP_006476872.1 arsenical pump membrane protein BAC0575 Protein 7e-103 60