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Name : TBXG_000458 (TBXG_000458) Accession : YP_006471919.1 Strain : Mycobacterium tuberculosis KZN 605 Genome accession: NC_018078 Putative virulence/resistance : Virulence Product : aldehyde dehydrogenase Function : - COG functional category : - COG ID : - EC number : - Position : 549935 - 551458 bp Length : 1524 bp Strand : + Note : - DNA sequence : ATGACTGTCTTTTCCCGTCCCGGTTCCGCCGGGGCGCTGATGTCCTATGAATCCCGGTACCAAAACTTCATCGGGGGCCA GTGGGTCGCGCCGGTCCATGGGCGCTACTTCGAGAACCCGACGCCGGTGACCGGCCAGCCGTTCTGCGAGGTGCCGCGCT CCGACGCGGCCGACATCGACAAGGCGCTCGACGCCGCGCACGCGGCGGCGCCGGGGTGGGGCAAGACCGCACCGGCCGAA CGGGCGGCGATCCTCAACATGATTGCCGACCGCATCGACAAGAACGCCGCCGCGCTGGCGGTGGCCGAGGTCTGGGACAA CGGGAAACCGGTCCGGGAAGCGCTGGCCGCCGATATCCCGTTGGCGGTCGATCACTTCCGGTACTTCGCCGCGGCGATTC GCGCCCAGGAGGGCGCGCTGAGCCAGATCGACGAGGACACCGTGGCCTACCACTTCCACGAGCCGCTCGGCGTGGTGGGC CAGATCATTCCGTGGAACTTCCCCATCCTGATGGCGGCCTGGAAGCTGGCGCCGGCGTTGGCGGCCGGCAACACGGCGGT GCTCAAACCCGCCGAGCAGACACCCGCTTCGGTGCTCTACCTGATGTCGCTGATCGGTGATCTGTTGCCGCCCGGGGTGG TCAACGTGGTCAACGGATTCGGCGCCGAGGCCGGCAAGCCGTTGGCCTCCAGCGACCGCATCGCCAAGGTCGCGTTCACC GGGGAAACCACCACGGGGCGGCTGATCATGCAATACGCCTCGCACAACCTGATCCCGGTCACCCTGGAACTCGGCGGCAA GAGCCCCAACATCTTCTTCGCCGACGTGCTGGCCGCCCACGACGACTTCTGCGACAAGGCGCTGGAAGGCTTCACCATGT TCGCCCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGCAGTCTGATCCAGGCCGACATCTACGACGAGTTCCTGGAG CTGGCGGCGATCCGGACCAAGGCGGTCCGGCAGGGCGACCCGCTGGACACCGAAACCATGCTGGGTTCCCAGGCCTCCAA CGACCAGCTGGAAAAGGTGTTGTCCTACATCGAAATCGGCAAGCAAGAGGGTGCGGTGATTATCGCCGGAGGCGAGCGCG CCGAACTAGGCGGCGACCTGTCCGGCGGTTATTACATGCAGCCGACGATCTTCACCGGCACCAACAACATGCGGATTTTC AAGGAGGAGATCTTCGGGCCGGTGGTCGCGGTGACGTCGTTCACCGATTACGACGACGCGATCGGCATCGCCAACGACAC CCTCTACGGCTTGGGTGCCGGTGTGTGGAGCCGCGACGGCAACACTGCCTATCGGGCCGGGCGGGACATCCAGGCCGGCC GGGTGTGGGTCAACTGCTACCACCTCTACCCCGCGCACGCGGCGTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGGGAG GGCCACCAGATGATGCTGCAGCACTACCAGCACACCAAGAACCTGCTGGTGTCCTACTCGGATAAGGCGCTGGGGTTCTT CTGA Protein sequence : MTVFSRPGSAGALMSYESRYQNFIGGQWVAPVHGRYFENPTPVTGQPFCEVPRSDAADIDKALDAAHAAAPGWGKTAPAE RAAILNMIADRIDKNAAALAVAEVWDNGKPVREALAADIPLAVDHFRYFAAAIRAQEGALSQIDEDTVAYHFHEPLGVVG QIIPWNFPILMAAWKLAPALAAGNTAVLKPAEQTPASVLYLMSLIGDLLPPGVVNVVNGFGAEAGKPLASSDRIAKVAFT GETTTGRLIMQYASHNLIPVTLELGGKSPNIFFADVLAAHDDFCDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLE LAAIRTKAVRQGDPLDTETMLGSQASNDQLEKVLSYIEIGKQEGAVIIAGGERAELGGDLSGGYYMQPTIFTGTNNMRIF KEEIFGPVVAVTSFTDYDDAIGIANDTLYGLGAGVWSRDGNTAYRAGRDIQAGRVWVNCYHLYPAHAAFGGYKQSGIGRE GHQMMLQHYQHTKNLLVSYSDKALGFF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 5e-128 | 60 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 7e-135 | 59 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 7e-135 | 59 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 7e-135 | 59 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 3e-134 | 59 |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 9e-58 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| TBXG_000458 | YP_006471919.1 | aldehyde dehydrogenase | VFG0082 | Protein | 2e-128 | 60 |
