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Name : TBXG_002335 (TBXG_002335) Accession : YP_006473821.1 Strain : Mycobacterium tuberculosis KZN 605 Genome accession: NC_018078 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase 2 lysX Function : - COG functional category : - COG ID : - EC number : - Position : 2570553 - 2574077 bp Length : 3525 bp Strand : + Note : - DNA sequence : GTGGGAGTGGGACTCCACTTAACTGTCCCTGGCCTTCGCCGGGATGGTCGCGGCGTCCAGTCTAACAGCCATGACACGTC ATCTAAGACAACGGCCGACATCAGCCGGTGCCCTCAGCACACCGATGCGGGGCTACAAAGGGCTGCAACGCCGGGCATTT CCCGGCTTTTGGGAATATCCTCGCGGTCTGTGACACTCACCAAACCTCGCTCGGCCACCAGGGGAAACTCCCGGTATCAC TGGGTTCCCGCGGCAGCCGGCTGGACCGTCGGCGTGATCGCGACCCTGTCACTACTGGCCAGTGTGTCGCCGTTGATTCG GTGGATCATCAAGGTTCCGCGCGAATTCATCAACGATTATCTGTTCAACTTCCCCGACACCAACTTCGCGTGGTCCTTCG TGCTGGCATTGCTGGCCGCCGCGTTAACGGCACGCAAACGCATTGCCTGGTTGGTCTTGCTGGCAAATATGGTCCTGGCC GCCGTGGTCAACGCCGCCGAGATCGCAGCGGGCGGCAACACCGCCGCCGAGAGCTTCGGGGAGAATCTCGGATTCGCCGT GCATGTTGTGGCAATCGTCGTTCTGGTGCTGGGCTATCGGGAGTTCTGGGCCAAGGTCCGCAGGGGCGCGCTGTTTCGGG CGGCTGCGGTGTGGCTTGCCGGCGCGGTGGTCGGAATCGTGGCGTCTTGGGGTCTGGTCGAACTGTTTCCGGGATCACTA GCGCCGGACGAGCGGTTGGGTTACGCGGCCAACCGGGTGGTCGGATTCGCCCTCGCCGATCCCGATCTGTTCACCGGCAG ACCGCACGTCTTCCTCAACGCGATCTTCGGGTTGTTCGGCGCGTTCGCGTTGATCGGGGCTGCGATCGTCTTGTTCCTAT CTCAGCGCGCTGACAATGCGCTGACCGGAGAGGACGAATCCGCTATCCGCGGGTTATTGGATTTGTATGGGAAGGACGAC TCACTGGGCTACTTCGCCACCCGTCGCGACAAGTCGGTGGTATTCGCATCCAGCGGCCGCGCCTGTATCACCTACCGTGT CGAGGTCGGTGTCTGCCTAGCCAGCGGCGACCCGGTAGGCGACCACAGAGCATGGCCGCAGGCCGTCGACGCGTGGCTGC GGCTGTGCCAGACCTACGGCTGGGCACCCGGCGTGATGGGCGCCAGTTCACAAGGGGCTCAGACATATCGCGAAGCGGGC CTAACCGCGCTCGAGCTGGGCGATGAGGCCATCCTGCGGCCAGCCGATTTCAAGTTGTCCGGCCCGGAGATGCGCGGGGT GCGCCAGGCCGTGACGCGGGCCCGGCGGGCGGGGTTGACGGTGCGCATCCGGCGGCATCGCGACATTGCCGAAGACGAGA TGGCGCAGACCATCACACGGGCGGATTCCTGGCGCGACACCGAGACCGAGCGCGGCTTCTCGATGGCGCTGGGCCGCCTC GGCGACCCCGCGGACTCCGACTGCCTGCTGGTGGAGGCGATTGATCCGCACAACCAGGTGCTGGCAATGCTGTCGCTGGT GCCGTGGGGAACCACCGGTGTCTCCCTGGATTTGATGCGTCGTTCTCCACAATCCCCGAACGGCACTATCGAACTTATGG TCAGCGAACTCGCCTTGCACGCTGAAAGCCTTGGTATCACTCGTATTTCGTTGAACTTCGCGGTGTTTCGCGCGGCCTTC GAGCAGGGCGCCCAACTCGGCGCCGGCCCGGTTGCCCGGTTGTGGCGGGGGCTGCTGGTCTTCTTCTCACGGTGGTGGCA GCTCGAGACGCTCTACCGCTCCAACATGAAGTACCAACCCGAATGGGTACCGCGCTACGCCTGCTACGAAGACGCCCGAG TGATTCCCCGAGTGGGCGTCGCCTCGGTGATCGCAGAGGGGTTCCTCGTGCTGCCGTTCAGCCGGCGCAACCGAGTACAC ACGGGGCATCATCCGGCAGTGCCCGAGCGGTTGGCGGCCACCGGCCTATTGCATCACGACGGCTCGGCACCGGACGTGAG CGGGCTGCGGCAAGTAGGCCTCACCAATGGCGACGGGGTCGAGCGGCGGCTACCCGAGCAGGTGCGAGTTCGGTTCGACA AGCTAGAGAAGCTGCGGAGCAGCGGCATTGACGCCTTTCCCGTGGGCCGGCCGCCCAGTCACACGGTGGCACAGGCGCTG GCCGCAGACCACCAGGCTAGCGTGTCGGTGTCCGGACGCATCATGCGAATACGTAACTACGGTGGTGTGTTGTTCGCCCA GCTGCGCGACTGGTCGGGCGAAATGCAAGTGCTGCTGGATAATTCACGCCTGGACCAGGGCTGCGCGGCCGACTTCAACG CGGCGACCGATCTGGGTGATCTGGTGGAGATGACCGGACACATGGGCGCCAGCAAGACCGGAACTCCATCGTTGATCGTC AGCGGCTGGCGCCTGATCGGTAAGTGTTTGCGACCGTTGCCGAATAAGTGGAAGGGGCTACTGGATCCCGAAGCCCGAGT CCGGACCCGTTACCTCGACCTGGCGGTCAACGCTGAGTCCCGTGCGCTGATCACCGCTCGCAGCAGCGTGCTGCGCGCTG TGCGCGAGACGCTGTTCGCAAAGGGATTCGTCGAGGTCGAAACGCCGATCCTACAGCAGCTGCACGGCGGCGCCACCGCC CGACCGTTCGTCACGCACATCAACACGTATTCCATGGATCTGTTCCTGCGCATCGCACCAGAGCTCTACCTCAAGCGCCT GTGCGTCGGCGGCGTGGAACGGGTATTCGAGCTCGGCCGTGCCTTTCGCAACGAGGGCGTCGACTTCAGCCACAACCCGG AGTTCACCCTACTGGAGGCCTATCAAGCACACGCCGACTACCTTGAGTGGATTGACGGCTGCCGCGAACTCATCCAGAAC GCCGCCCAGGCCGCCAACGGGGCGCCCATCGCCATGCGGCCCCGGACGGACAAGGGTTCCGACGGCACCCGCCACCACCT CGAACCGGTCGACATCTCCGGGATATGGCCGGTGCGGACGGTGCATGATGCGATCTCGGAAGCACTCGGTGAACGCATCG ACGCCGATACCGGCTTGACCACTCTCCGCAAGCTGTGCGACGCCGCCGGTGTCCCCTATCGGACCCAATGGGATGCCGGC GCGGTCGTGCTCGAGCTATACGAGCACCTGGTGGAGTGCCGCACCGAGCAACCGACGTTCTACATCGACTTTCCGACATC GGTGTCACCGTTGACCCGACCGCATCGCAGCAAGCGCGGTGTCGCCGAGCGTTGGGACCTGGTGGCGTGGGGTATCGAGC TGGGCACCGCCTACAGCGAGCTGACCGACCCGGTGGAGCAACGGCGCCGCCTGCAGGAGCAGTCCCTGCTGGCCGCCGGC GGAGACCCCGAGGCGATGGAACTCGACGAAGACTTCCTGCAAGCGATGGAGTACGCCATGCCGCCCACCGGCGGCTTGGG CATGGGCATTGACCGGGTGGTCATGCTGATCACTGGGCGCAGCATTCGCGAAACACTGCCCTTTCCGTTGGCAAAACCGC ATTAG Protein sequence : MGVGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYH WVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLA AVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSL APDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDD SLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAG LTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRL GDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAF EQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVH TGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQAL AADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIV SGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATA RPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLEWIDGCRELIQN AAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAG AVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAG GDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 3e-155 | 43 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-155 | 43 |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-155 | 43 |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-155 | 43 |
