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Name : TBXG_001209 (TBXG_001209) Accession : YP_006472682.1 Strain : Mycobacterium tuberculosis KZN 605 Genome accession: NC_018078 Putative virulence/resistance : Unknown Product : type I restriction/modification system DNA methylase hsdM Function : - COG functional category : - COG ID : - EC number : - Position : 1345045 - 1346667 bp Length : 1623 bp Strand : + Note : - DNA sequence : ATGCCGCCCAGGAAGAAGCAGGCGCCGCAGGCGCCGTCGACGATGAAGGAGCTCAAAGACACGCTCTGGAAGGCCGCCGA CAAGCTGCGCGGGTCGCTGTCGGCCAGCCAATACAAGGACGTGATCCTCGGCCTGGTGTTCCTTAAGTACGTGTCCGACG CGTATGACGAACGGCGCGAGGCAATCCGTGCCGAGTTGGCGGCCGAAGGAATGGAGGAGTCTCAGATAGAAGACCTGATC GACGATCCCGAGCAGTACCAGGGTTACGGCGTATTCGTCGTGCCGGTGAGTGCGCGCTGGAAGTTCTTGGCAGAGAACAC AAAAGGCAAGCCAGCCGTTGGTGGTGAGCCGGCGAAGAACATCGGTCAGCTGATCGACGAGGCGATGGACGCGGTAATGA AGGCCAATCCAACACTCGGTGGGACGCTGCCGAGGCTGTATAACAAGGACAACATCGACCAGCGCCGGCTCGGTGAGCTG ATCGACCTATTTAACAGTGCGCGCTTCAGCCGGCAGGGCGAGCACCGCGCCCGGGATCTGATGGGTGAGGTCTACGAATA CTTCCTCGGCAATTTCGCTCGCGCGGAAGGGAAGCGGGGTGGCGAGTTCTTTACCCCGCCCAGCGTGGTCAAGGTGATCG TGGAGGTGCTGGAGCCGTCGAGTGGGCGGGTGTATGACCCGTGCTGCGGTTCCGGAGGCATGTTTGTGCAGACCGAGAAG TTCATCTACGAACACGACGGCGATCCGAAGGATGTCTCGATCTATGGCCAGGAAAGCATTGAGGAGACCTGGCGGATGGC GAAGATGAACCTCGCCATCCACGGCATCGACAACAAGGGGCTCGGCGCCCGATGGAGTGATACCTTCGCCCGCGACCAGC ACCCGGACGTGCAGATGGACTACGTGATGGCCAATCTGCCGTTCAACATCAAAGACTGGGCCCGCAACGAGGAAGACCCA CGCTGGCGCTTCGGTGTTCCGCCCGCCAATAACGCCAACTACGCATGGATTCAGCACATCCTGTACAAGTTGGCGCCGGG AGGTCGGGCGGGCGTGGTGATGGCCAACGGGTCGATGTCGTCGAACTCCAACGGCGAGGGGGATATTCGCGCGCAGATCG TGGAGGCGGATTTGGTTTCCTGCATGGTCGCGTTACCCACCCAGCTGTTCCGCAGCACCGGAATCCCGGTGTGCCTGTGG TTTTTCGCCAAAGACAAGGCGGCAGGTAAGCAAGGGTCTATCGACCGGTGCGGGCAGGTGCTGTTCATCGACGCTCGTGA ACTGGGCGACCTAGTGGACCGGGCCGAGCGGGCGCTGACCAACGAGGAGATCGTCCGCATCGGGGATACCTTCCACGCGT GGCGCGGGTCGAAGTCGGCTGCCGTCAAAGGGATTATGTACGAGGATGTTCCGGGGTTCTGTAAGTCGGCGACGTTGGCG GAGATCAAGGCGACCGACTATGCGCTCACGCCGGGGCGGTATGTGGGTACGCCCGCGGTCGAGGACGACGGAGAGCCGAT CGACGAGAAGATGGCCCGGTTGTCGAAGGCGTTGCTGGAGGCGTTCGATGAGTCGGCGCGGCTGGAAAGGGTCGTGCGGG AGCAACTGGGGCGGCTTAGATGA Protein sequence : MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEESQIEDLI DDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGEL IDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKDWARNEEDP RWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLW FFAKDKAAGKQGSIDRCGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdM | YP_251979.1 | type I restriction-modification system DNA methylase | Not tested | SCCmec | Protein | 6e-122 | 49 |
| hsdM | BAH57701.1 | type I restriction-modification system DNA methylase | Not tested | Type-VII SCCmec | Protein | 3e-122 | 49 |
| hsdM | BAD24842.1 | HsdM protein | Not tested | Type-V SCCmec | Protein | 3e-121 | 48 |
| api49 | CAF28523.1 | putative HsdM-like N-methyl transferase | Not tested | YAPI | Protein | 7e-107 | 45 |
