Gene Information

Name : guaA (SCIM_0865)
Accession : YP_006469767.1
Strain : Streptococcus intermedius JTH08
Genome accession: NC_018073
Putative virulence/resistance : Unknown
Product : bifunctional GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 995677 - 997236 bp
Length : 1560 bp
Strand : -
Note : glutamine amidotransferase protein

DNA sequence :
ATGACAATTACAACTGAATTGCAAGATGTTGAAAGAATCATTGTATTGGATTATGGCAGTCAATATAATCAACTCATCTC
ACGCCGTATACGCGAGATTGGTGTTTTTTCTGAACTAAAAAGTAATAAAATTACAGCTGCTGAAGTTCGTGAAATAAATC
CAGTCGGAATTATCCTGTCTGGTGGGCCAAATTCTGTTTATGAAGAAGGTTCATTTGATCTTGACCCTGAAATTTTGGAA
TTGGGCATTCCGATTTTAGGGATTTGTTATGGCATGCAGCTTTTAACTCACAAATTAGGCGGAAAAGTTGTACCCGCAAG
AAACGCTGGAAATCGTGAGTACGGTCAGTCAGAACTCATTCATACGGATTCACAACTGTTTGCAAGCACTCCTGAACAAC
AAATTGTTCTTATGAGTCATGGAGACGCTGTTACAGAAATTCCTCAAGGGTTTGTACGAACCGGAACTTCTGCCGACTGT
CCATTTGCAGCTATTGAAAATACCTCCAAGAAAATCTACGGCATTCAGTTCCACCCTGAGGTTCGTCATTCAGAATTTGG
CTACGATATTCTTCGCAACTTTGCTCTTGATATTTGTGGAGCCAAAGGCGACTGGTCTATGGATAATTTTATTGATATGC
AAATTAAGCAAATTCGAGAAACTGTTGGAGATAAACGCGTTCTTCTGGGTCTATCGGGTGGTGTCGATTCATCAGTTGTT
GGTGTTCTCCTTCAAAAAGCTATTGGAGACCAGCTTATCTGTATTTTTGTAGATCATGGCTTACTCCGTAAGGGAGAGGC
GGAGCAAGTTATGGATTCTCTTGGCGGGAAATTTGGTCTTAATATTATTAAAGCAGATGCTGCCAAGCGTTTCCTTGGTA
AATTAGCTGGTGTATCTGATCCAGAACAAAAGCGTAAAATCATTGGTAATGAGTTTGTTTATGTTTTTGACGATGAAGCT
AGCAAGTTAAAAGATGTAAAATTCCTCGCACAAGGAACGCTTTATACTGACGTTATCGAATCTGGTACAGATACTGCTCA
AACTATCAAGTCTCACCATAATGTTGGTGGTCTGCCAGAAGACATGCAGTTTGAGTTGATTGAGCCTCTCAATACACTTT
ATAAAGACGAAGTTCGTGCGCTTGGTACAGAACTTGGTATGCCAGATGAAATTGTTTGGCGTCAGCCATTCCCAGGCCCA
GGACTTGCCATTCGTATTATGGGCGAGATTACTGAAGAAAAACTCACAACTGTTCGTGAATCTGATGCCATTCTTCGCGA
AGAAATCGTGAAAGCTGGACTCGATCGTGATATTTGGCAATACTTCACTGTGAATACTGGTGTTCGTTCGGTAGGTGTCA
TGGGAGATGGTCGAACTTATGACTATACTATTGCAATTCGTGCTATTACTTCTATTGATGGAATGACTGCAGATTTTGCT
AAAATTCCTTGGGAAGTATTGCAAAAAATCTCTGTTCGTATCGTCAATGAAGTAGCTCATGTTAATCGTATTGTCTACGA
TATTACTAGCAAGCCACCAGCAACGGTTGAGTGGGAATGA

Protein sequence :
MTITTELQDVERIIVLDYGSQYNQLISRRIREIGVFSELKSNKITAAEVREINPVGIILSGGPNSVYEEGSFDLDPEILE
LGIPILGICYGMQLLTHKLGGKVVPARNAGNREYGQSELIHTDSQLFASTPEQQIVLMSHGDAVTEIPQGFVRTGTSADC
PFAAIENTSKKIYGIQFHPEVRHSEFGYDILRNFALDICGAKGDWSMDNFIDMQIKQIRETVGDKRVLLGLSGGVDSSVV
GVLLQKAIGDQLICIFVDHGLLRKGEAEQVMDSLGGKFGLNIIKADAAKRFLGKLAGVSDPEQKRKIIGNEFVYVFDDEA
SKLKDVKFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDEIVWRQPFPGP
GLAIRIMGEITEEKLTTVRESDAILREEIVKAGLDRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFA
KIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-164 69
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-164 69
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-164 69
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-115 52