Gene Information

Name : clpC (SCIM_0107)
Accession : YP_006469009.1
Strain : Streptococcus intermedius JTH08
Genome accession: NC_018073
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 135861 - 138290 bp
Length : 2430 bp
Strand : +
Note : -

DNA sequence :
ATGAAATATTCAAAAGCTTTGACAGAAAGTATTGAATCAGCACAGTTATTAGCAAGTCATTTTGAAACGGATTATTTAGA
GTCTTGGCAGCTGTTGATTGCTATGGCAAATAATCCTTATAGTGTTGCTGGTTCAGTTTTAAATGATTACCCACTTGAAA
TTGATGATTTTGAAAAGGCAGCTTTTCATATCACGGGGAAAGTCTATCAACAAGAGGGAGACTTTACTATTTGGCCGTTT
TCTTATCGCATGAAAGTGCTATTTTTGACTGCTGAACAAATTGCAGGGGCGGTTCATGCTAATAATCTTGGGACAGAGCA
TATATTGCTAGCTATGTTATTTGACCAAGGAAGCTTGGCAGCGCGTATTCTTGAATTTATTGGTTTTAGTTACGAAGATA
AAGAAGGCGTTTTGCGCATGACAGATCTGCGGAAAAATTTAGAGCATAAGGCCAGCTGGAATAAAGAGGATTTAAAGGCT
ATTCGTCACCTAAATAAAAGTGCTGCAGCAACAAGACAAACGATGGCTAATATGATGGGAATGCCTCCTGCAACCAGTGG
CGGACTAGAAGATTATACTCGTGATCTAACTGAAATGGCTCATATGGGCCTTTTAGAACCGATCATTGGGCGGGATAAAG
AGATTTCTCGCATACTTCAGATTTTAAGTCGTAAGACAAAAAACAATCCGGTTTTGGTAGGAGATGCAGGAGTTGGGAAG
ACAGCATTAGCTCTGGGTTTGGCGCAACGTGTGGCAGATGGTCAAGTTCCAAATGAGCTTGCAAAGATGAGAGTTTTAGA
GCTAGATTTAATGAATGTGGTGGCTGGAACTCGTTTTCGTGGTGATTTTGAAGAACGGATGAACAATATTATCAATGATA
TTGAAGCAGATGGGCATGTTATTCTCTTCATTGATGAGCTTCATACCATTATGGGTTCTGGCAGCGGGATTGACTCGACA
TTAGATGCAGCAAATATTCTCAAGCCGGCTTTGGCTAAAGGAACGCTCAGAACGATCGGTGCAACAACACAAGAAGAGTA
CCAAAAATATATCGAAAAAGATGCAGCTCTTTCACGAAGATTTGCCAAGGTTACTATTGAAGAAGCAACGGTAGCTGACA
GCATTGCTATTTTACAGGGACTCAAGAAAAGTTATGAAGATCACCACAAGGTCGTGATTACGGATTCGGCAATTGAGACG
GCTGTTAAGTATGCGCATCGTTACCTGACTAGTAAACATCTACCTGACTCAGCGATTGACTTGCTAGACGAAGCTGCTGC
AAGGGTACAAAATAAAAGCCCGCAAAATCACGTAAAAGCAGAATTGAGTGCAGCAGATGAGGCTTTAATGGCAGGCGATT
GGAACAAAGTTGATACGTTGTTGGAGAAAGAGAGTCAGCCAATTGTTTATAAATTAAGGGTGAAAGACGAGGATGTTTTA
GCAACACTCAGCAGTTTATCAGGTATTCCTGTGCAAAAGTTGACACAAACAGATGCGAAGAAATACCTCAATTTAGAAAA
GGAGTTACACAAACGAGTTATCGGGCAGAATGAAGCAATTTCTGCTATTAGTCGAGCGATTCGGCGCAATCAATCTGGTA
TCCGCACTAGCAAGCGCCCAATTGGCTCCTTTATGTTCTTAGGGCCAACCGGGGTCGGAAAAACTGAGCTAGCTAAGGCT
TTGGCAGAAGTTCTCTTTGATGACGAAACAGCGTTAATTCGTTTTGATATGTCCGAATACATGGAGAAATTTGCTGCTAG
TCGTCTCAATGGAGCACCTCCAGGCTATGTTGGTTATGAAGAAGGGGGAGAATTAACTGAAAAGGTGCGTAATCGTCCTT
ACTCTGTGCTCCTCTTTGACGAAGTGGAAAAAGCTCATCCTGATATTTTCAATGTGCTGCTCCAAGTCCTAGATGACGGG
GTTCTGACGGATAGCAAGGGCCGTAAGGTAGATTTTTCCAATACTATTATCATTATGACCAGCAATCTTGGTGCGACAAG
TTTACGGGACGATAAGACGGTTGGGTTCGGAGCAAGAGATGTTCGCTTTGATCATGAAAATATGGAAAAACGAATGATGG
AAGAGCTAAAGAAAGCTTATCGTCCAGAATTTATTAACCGAATTGATGAAAAGGTTGTTTTTCACAGTTTGACTAGCGAA
GACATGCAGGAAGTGGTGAAAATTATGGTGCAACCGCTCATTTCTAGTCTTGCAGAAAAAGGAATTAAACTCAAATTCCA
ACCGAGTGCTTTGAAGCTTCTAGCTCAAGAGGGCTATGATCCTGAAATGGGAGCTCGTCCATTGCGTCGAATTCTACAAA
CTCGAGTGGAAGACCATTTATCAGAATTACTTTTAGCAGGTGAGCTAAAAACGGGGCAAAGCTTGAAAGTCGGTGTCAAG
GCTGGAAAATTGAAGTTTGAAGTGCTCTGA

Protein sequence :
MKYSKALTESIESAQLLASHFETDYLESWQLLIAMANNPYSVAGSVLNDYPLEIDDFEKAAFHITGKVYQQEGDFTIWPF
SYRMKVLFLTAEQIAGAVHANNLGTEHILLAMLFDQGSLAARILEFIGFSYEDKEGVLRMTDLRKNLEHKASWNKEDLKA
IRHLNKSAAATRQTMANMMGMPPATSGGLEDYTRDLTEMAHMGLLEPIIGRDKEISRILQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVADGQVPNELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEADGHVILFIDELHTIMGSGSGIDST
LDAANILKPALAKGTLRTIGATTQEEYQKYIEKDAALSRRFAKVTIEEATVADSIAILQGLKKSYEDHHKVVITDSAIET
AVKYAHRYLTSKHLPDSAIDLLDEAAARVQNKSPQNHVKAELSAADEALMAGDWNKVDTLLEKESQPIVYKLRVKDEDVL
ATLSSLSGIPVQKLTQTDAKKYLNLEKELHKRVIGQNEAISAISRAIRRNQSGIRTSKRPIGSFMFLGPTGVGKTELAKA
LAEVLFDDETALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDVRFDHENMEKRMMEELKKAYRPEFINRIDEKVVFHSLTSE
DMQEVVKIMVQPLISSLAEKGIKLKFQPSALKLLAQEGYDPEMGARPLRRILQTRVEDHLSELLLAGELKTGQSLKVGVK
AGKLKFEVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 8e-141 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_006469009.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 5e-165 47
clpC YP_006469009.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 3e-124 44