Gene Information

Name : pykF (SCIM_1063)
Accession : YP_006469965.1
Strain : Streptococcus intermedius JTH08
Genome accession: NC_018073
Putative virulence/resistance : Virulence
Product : pyruvate kinase I
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1208432 - 1209934 bp
Length : 1503 bp
Strand : -
Note : fructose-stimulated

DNA sequence :
ATGAATAAACGTGTAAAAATCGTTGCAACTTTAGGTCCTGCGGTAGAAATCCGTGGTGGTAAAAAATTTGGTGAAGATGG
ATATTGGAGTGAAAAACTTGATGTTGAATCATCTGCACAAAATATCGCTAAATTGATTGAGGCCGGAGCAAACACTTTCC
GTTTCAACTTCTCACATGGTGACCACGCAGAACAAGGTGACCGTATGGCTACTGTTCATCGTGCCGAAGAAATTGCTGGT
CAAAAAGTTGGTTATCTTCTTGACACAAAAGGTCCTGAAATTCGTACAGAATTATTTGAAAGCGACGCTAAAGAATACTC
TTACAAAACGGGTGAAAAGATTCGTGTTGCAACTAAACAAGGTATTAAATCCACTCGCGAAGTTATCGCTTTGAATGTTG
CAGGTGGGCTTGATATTTATGACGATGTTGAAGTTGGAAAACAAGTTCTTGTTGACGATGGAAAACTTGGCCTTCGTGTT
ATTGCAAAAGATCCTGCTACACGTGAATTTGAAGTAGAAGTTGAAAACGACGGTGTTATCGCTAAACAAAAAGGTGTTAA
TATTCCAAATACAAAAATTCCTTTCCCAGCACTTGCTGAACGTGATAATGACGATATTCGCTTTGGTTTAGAACAAGGAA
TCAACTTCATTGCTATTTCATTTGTACGTACTGCAAAGGATGTCAATGAAGTTCGTGCAATCTGTGAAGAAACTGGTAAT
GGACATGTGAAATTGTTTGCTAAAATCGAAAATCAACAAGGTATCGAAAACTTGGATGAGATCATCGAAGCTGCTGATGG
TATTATGATTGCTCGTGGTGACATGGGTATCGAAGTACCATTTGAAATGGTTCCAGTTTACCAAAAAATGATTATCACAA
AAGTCAATGCTGCTGGTAAAATTGCTATTACAGCAACAAATATGCTTGAAACAATGACTGAAAAACCACGTGCTACTCGT
TCAGAAGTATCAGATGTGTTCAATGCTGTTATTGATGGAACAGATGCGACAATGCTTTCAGGTGAATCTGCAAATGGTAA
ATATCCACTTGAATCTGTAACGACAATGGCAACAATTGATAAAAATGCTCAAACTCTCTTGAATGAATATGGACGTTTGT
CATCAGTTGACTATGCTCGTAGCTCTAAGACAGAGGTTGTTGCTTCAGCTGTTAAAGATGCTACAAACTCAATGGACATC
AAATTGGTTGTGACAATTACTGAAACAGGTAACACTGCACGTTTGATTTCTAAGTATCGTCCTGATACTGATATTTTAGC
AGTAACATTTGATGAATTGACTCAACGTTCATTGATGTTGAATTGGGGTGTCATTCCAGTTGTAACTGAAAAACCTGCAT
CAACTGATGATATGTTTGAAGTTGCTGAAAAAGTTGCTCTTGCAAGTGGTCTTGTGGAATCTGGCGACAATATTGTGATT
GTGGCTGGTGTACCAGTTGGAACTGGTGGAACAAACACTATGCGTATTCGTACAGTACGTTAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWSEKLDVESSAQNIAKLIEAGANTFRFNFSHGDHAEQGDRMATVHRAEEIAG
QKVGYLLDTKGPEIRTELFESDAKEYSYKTGEKIRVATKQGIKSTREVIALNVAGGLDIYDDVEVGKQVLVDDGKLGLRV
IAKDPATREFEVEVENDGVIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGN
GHVKLFAKIENQQGIENLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKIAITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQTLLNEYGRLSSVDYARSSKTEVVASAVKDATNSMDI
KLVVTITETGNTARLISKYRPDTDILAVTFDELTQRSLMLNWGVIPVVTEKPASTDDMFEVAEKVALASGLVESGDNIVI
VAGVPVGTGGTNTMRIRTVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-82 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-82 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-82 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-82 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_006469965.1 pyruvate kinase I VFG0479 Protein 2e-82 44