Gene Information

Name : Desaci_3957 (Desaci_3957)
Accession : YP_006468159.1
Strain : Desulfosporosinus acidiphilus SJ4
Genome accession: NC_018068
Putative virulence/resistance : Resistance
Product : heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4111223 - 4113097 bp
Length : 1875 bp
Strand : +
Note : PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-transloc

DNA sequence :
ATGAGAACATCTTGGGATATCCTTTGGTCGCGACATAAAGGGTTGATTGTTACAGCCCTCAGCTTTGGATTAATTATCCT
GGCTTGGTATTCTGGCAGATATGGTCATACTCAGCTAGAAATTCCATTCTACGTATTGACCTATGCAATAGGTGGATATC
AAAAAGCCTGGGAAGGTCTGCAAACCCTGATTAAAGAAAATGATTTCGATGTCGATTTGCTCATGGTCGTAGCGGCTATT
GGTGCAGCCAGTATCGGATTTTGGAGAGACGGGGCTATTTTAATTCTAATCTTTTCACTGAGTGGTGCTTTAGAAGGATA
TACTTTGGAGCGAACGAATGATGAAATTAAGGCCATAATGAAACTACGCCCGGAAGAGGCGATTGTGTTACAAGGAAACG
TGGAAAAGCGAGTTCGAGTCGAGGAATTGCAGCAAGGCGACCGTTTGCTGGTGAGACCGGGAGAAAGGATTGCGGCGGAT
GGGCTTGTGCATGAGGGATATTCTTCTGTGAATCAGGCATCTATTACTGGAGAATCGATGCCCATGGACAAAATTCCAGG
TGATGAGGTTTTTGCCGGAACCATGAACGGACAGGGAGCTTTAGTCATCGAAATGACCAAACCCGCAGAGGCAACGTTGC
TTGCTAAAATAATTCATCTTGTTCAGGAGGCTCAAAGTGAAAGACCCCCCAGTCAATTATACATGGAGCGTTTTGAACGT
ATTTATGCAAAAATTGTGGTCACTGGTGCAGTTTTGATTTCAATCGTGCCACCCTTTGTCTTAGGGTGGTCATGGAGTGA
GACAATTTACAAAGCGATGATCTTTCTCGTCGTAGCCTCTCCTTGTGCTTTGGTTTCCTCCATCATGCCTGCTATTTTAT
CTGGGATATCCAATGGAGCACGAAATGGCATATTATTTAAAGGAGGCGCCTATCTAGAAGCTATCGGTGACGTAAGCGTA
GTAGCTTTTGACAAAACCGGAACTCTCACGGAGGGAATACCGAGAATCACTCAAGTGGTACCTTATGGAAGCTATACTGA
AAATGAGGTATTATGCATCGCGGCCTCCCTGGAAACTTGGTCAGAACACCCCATTGCTAAGGCAATAATCCGTAAGGCAA
AGGAGGAAAATATCCAACTTTGCTCGACTTCAAAACTAGAAGCTGTGCCAGGGCTTGGGGTTCGTGGCATAGTGGACGGT
CAGGAACATAGAATTGGAAAACTAGATTTGACCGAAGGACAAAAATTGTCGAAAGAGGAAATGAAGGCTGTCCAGAAACT
GGAGAAGCAAGGGAATACAGTGATCTTTGTTCAGGTGGAAAAAGAACGAATCGGTGTTTTAGCGGTACAAGATACCCTAC
GACCACAAGCAAAAGAATCGATCAAAAGACTAAAGAAAATGGGTATTAAGGTTGTGATGCTGACCGGCGACAGTGCTTCA
ACCGCGCAAATCATAGGTGAGCAGGTAGGCGTCGATCAAGTATATTCAGAACTGCTGCCGGAAGATAAAGTAGACATTAT
TAGAAAATTAGGGGAATATGGAAAAGTAGCCATGGTCGGCGATGGTGTTAACGATGCACCGGCCTTGGCGGTTTCTGCTG
TGGGTATCGCTATGGGTGCTGCCGGAACCGATGTCGCGTTGGAAACTGCTAATGTTGTTTTGATGGCTGATGATATTTCT
AAGGTTGCTTACGCCATTACCTTAGGACGTCGCACGACTAGGGTGGTTAAACAAAATGTGGCTTTTGCCATTGCCGTCAT
TCTCGTGCTGGTCCTGTCTAATTTTTTCGGGAATATTATTCTACCTGTAGGAGTCATCGGACACGAAGGGAGTACTATCC
TTGTCATCATCAGTGGTCTACGTTTACTACGGTAA

Protein sequence :
MRTSWDILWSRHKGLIVTALSFGLIILAWYSGRYGHTQLEIPFYVLTYAIGGYQKAWEGLQTLIKENDFDVDLLMVVAAI
GAASIGFWRDGAILILIFSLSGALEGYTLERTNDEIKAIMKLRPEEAIVLQGNVEKRVRVEELQQGDRLLVRPGERIAAD
GLVHEGYSSVNQASITGESMPMDKIPGDEVFAGTMNGQGALVIEMTKPAEATLLAKIIHLVQEAQSERPPSQLYMERFER
IYAKIVVTGAVLISIVPPFVLGWSWSETIYKAMIFLVVASPCALVSSIMPAILSGISNGARNGILFKGGAYLEAIGDVSV
VAFDKTGTLTEGIPRITQVVPYGSYTENEVLCIAASLETWSEHPIAKAIIRKAKEENIQLCSTSKLEAVPGLGVRGIVDG
QEHRIGKLDLTEGQKLSKEEMKAVQKLEKQGNTVIFVQVEKERIGVLAVQDTLRPQAKESIKRLKKMGIKVVMLTGDSAS
TAQIIGEQVGVDQVYSELLPEDKVDIIRKLGEYGKVAMVGDGVNDAPALAVSAVGIAMGAAGTDVALETANVVLMADDIS
KVAYAITLGRRTTRVVKQNVAFAIAVILVLVLSNFFGNIILPVGVIGHEGSTILVIISGLRLLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 6e-113 43
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-110 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-110 42
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 5e-86 41
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 4e-86 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desaci_3957 YP_006468159.1 heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0092 Protein 1e-146 54
Desaci_3957 YP_006468159.1 heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0099 Protein 8e-98 42
Desaci_3957 YP_006468159.1 heavy metal-translocating P-type ATPase, Cd/Co/Hg/Pb/Zn-transporting BAC0124 Protein 6e-91 41