Gene Information

Name : Desaci_3824 (Desaci_3824)
Accession : YP_006468037.1
Strain : Desulfosporosinus acidiphilus SJ4
Genome accession: NC_018068
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase, FliI/YscN
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.15
Position : 3981306 - 3982613 bp
Length : 1308 bp
Strand : -
Note : PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family; flagellar protein export ATPase FliI

DNA sequence :
ATGGGAGTTTGGGAATTAATGCTTCAGAAGGCGGAGGAGATTGACCCTGTCTCTGCCCAAGGAAGGGTTTCCAAAATTGT
AGGACTGATGATTGAATCTGCCGGTCCGAGAGTGAGTGTGGGTGAGTACTGTCATATTCTTACTCGCGCCGGAAATGAAC
TTCCCGCAGAGGTAGTTGGCTTTCGTGATTCCACGGCTCTCTTAATGCCTTTAGGGGAACTTGAAGGAATTGCTCCCGGC
GACCGCGTGATCCCTCAAAGGCAGAAGTTAACCGTTTCAGTAGGGTCCGGACTTTTGGGGCGAATTCTCAATGGTTTGGG
ACATCCCATCGATGGGCGTCCGCTTAAGACCGAAAACTCTTACCCTTTGCAAAATAAGCCGCCTAACGCCCTCTTACGTC
CACGAATAACGGACGTTCTCAGTGTAGGAGTAAGAACGATTGATGGGCTGCTAACCCTTGGCCGCGGGCAACGGATGGGA
ATCTTTGCCGGTTCCGGTGTAGGTAAAAGCACCTTATTGGGAATGATGGCCAGAAATACCGTGGCTGATGTCAACGTTAT
TGCTCTGGTAGGGGAACGGGGGCGGGAATTGAGGGACTTTATTGAGAAAGATCTTGGACCCGCAGGATTAGCACGTTCTG
TAATTGTTGTGGCGACATCGGATCAACCGGCATTAGTTCGCTTAAAAGCTGCTTTTACCGCTACTGCAGTGGCTGAGTTT
TTTCGAGATCAAGGTAAGGATGTACTGTTAATGATGGACTCTGTAACACGCTTTGCCATGGCTCAGCGAGAAGTGGGGCT
TACGGTGGGCGAACCTCCTGCAACCCGAGGATATCCGCCTTCTGTATTTGCACTTTTACCAAAACTTTTAGAGCGTTCCG
GAATGGCGGAGAAGGGAAGCATCACCGGAATTTATACAGTGTTGGTGGATGGCGATGATCACAATGAGCCAATTGCCGAT
ACTGTGCGCGGGATTCTGGATGGACATATTGTTTTAACACGGGACCTTGCCATGCAGAATCATTACCCAGCGATTGATAT
TTTACAGTCCGTGAGTCGGGTGATGAATGATGTTGTTAGTCCAGTTCATAAAGACTTGGCTTCAAAATTTCGGGAACATC
TTGCGGTTTACCGTGATGCCAAAGATCTGATTGACATTGGAGCCTATACTTCGGGAAGCAATCCCAGGATTGATTCCGCT
ATTGCGTATATAGAACGGATTCAGGAGTTTACTAGGCAAGGAGTCTCAGAAAGTTCGGGATTCGAAGAGACGCTTCAGCA
GCTTAACGGAATCTATGCTCTAGAGTGA

Protein sequence :
MGVWELMLQKAEEIDPVSAQGRVSKIVGLMIESAGPRVSVGEYCHILTRAGNELPAEVVGFRDSTALLMPLGELEGIAPG
DRVIPQRQKLTVSVGSGLLGRILNGLGHPIDGRPLKTENSYPLQNKPPNALLRPRITDVLSVGVRTIDGLLTLGRGQRMG
IFAGSGVGKSTLLGMMARNTVADVNVIALVGERGRELRDFIEKDLGPAGLARSVIVVATSDQPALVRLKAAFTATAVAEF
FRDQGKDVLLMMDSVTRFAMAQREVGLTVGEPPATRGYPPSVFALLPKLLERSGMAEKGSITGIYTVLVDGDDHNEPIAD
TVRGILDGHIVLTRDLAMQNHYPAIDILQSVSRVMNDVVSPVHKDLASKFREHLAVYRDAKDLIDIGAYTSGSNPRIDSA
IAYIERIQEFTRQGVSESSGFEETLQQLNGIYALE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 6e-99 54
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-98 54
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-99 54
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-99 54
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-98 54
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-99 54
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-99 54
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-99 54
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-100 54
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-100 54
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 7e-85 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 4e-83 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-83 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-83 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-83 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-84 49
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-83 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-83 49
escN AAL57542.1 EscN Virulence LEE Protein 1e-84 49
escN AAC31513.1 L0034 Virulence LEE Protein 9e-85 49
escN YP_003223475.1 translocator EscN Virulence LEE Protein 6e-85 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 9e-85 49
escN CAC81862.1 EscN protein Virulence LEE II Protein 7e-85 49
escN CAI43874.1 EscN protein Virulence LEE Protein 5e-85 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-84 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-84 49
escN AAK26715.1 EscN Virulence LEE Protein 1e-84 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-84 49
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-82 49
escN AAC38383.1 EscN Virulence LEE Protein 7e-85 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-86 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-78 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-83 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-83 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-85 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 9e-84 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-85 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-75 45
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-65 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-80 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 8e-81 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-81 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-75 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-75 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-64 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-64 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-64 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-64 42
invC AAS66861.1 InvC Not tested SSR-2 Protein 6e-64 41
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 4e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG0192 Protein 6e-100 53
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG0048 Protein 2e-102 53
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG0390 Protein 2e-96 53
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG2144 Protein 5e-105 52
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG1254 Protein 7e-99 51
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG2499 Protein 1e-95 51
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG2331 Protein 8e-94 49
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG0515 Protein 7e-84 49
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG0812 Protein 5e-85 49
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG0730 Protein 4e-85 49
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG1778 Protein 3e-68 44
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG0555 Protein 5e-65 42
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG1008 Protein 9e-65 42
Desaci_3824 YP_006468037.1 type III secretion system ATPase, FliI/YscN VFG2459 Protein 6e-75 41