Gene Information

Name : A458_03335 (A458_03335)
Accession : YP_006456344.1
Strain : Pseudomonas stutzeri CCUG 29243
Genome accession: NC_018028
Putative virulence/resistance : Resistance
Product : RND efflux transporter
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 744650 - 747694 bp
Length : 3045 bp
Strand : -
Note : COG0841 Cation/multidrug efflux pump

DNA sequence :
ATGGATTTCGCCCGCTACGCCATCACCCGCCCGGTCAACATCTGGATTCTGATACTGATCTGCCTGCTCGGCGGCACCCT
CGCCTTCTTCGAGATCGGCCGCCTGGAAGACCCGGAATTCACCATCAAGCAGGCCATCGTCAACGTGCAGTATCCCGGCG
CCACGGCGCTGGAGGTCGAACAGCAGGTGACCGAACCGCTGGAAAGCGCGATCCAGCAGATGTCGCAGATCAAGGAGCTC
CGCTCACGCTCGATGCCGGGCATCGCCGAGATTCGCGTGGAGATGCAGGACCGCTACGACGGCGATGCGCTACCGCAGAT
CTGGGACGAGCTGCGCAACAAGATCAACGATGCCCAGGGCGACCTGCCGCCGGGGATCGAACCGCCGCAGGTCAACGATG
ATTTCGGCGACGTCTACGGCATCTTCTACGCGCTGACCGGCGATGGCCTGACGCTAAAGGAGCTCCACGAAACGACCAAG
GATCTGCGCCGCGCGCTGGTGGCCGCCGACGGCGTCGGCAAGGTCGAGATCGCCGGCGTGCAGGAAGAGCGCATCCTCGT
GGAAGTCGACCAGGCGCAGCTGGCCGCGATGGGCATCGCCCCCGACGAGATCGCGGCGGCGCTGGCCGATACCGATGCCG
CGGTAGATGCCGGCGGCGTGCATGCCGGCGAGTACTTCGTGCGCCTGCGCCCGAGCGGCGCCTTCGATTCGCTCGAAGAG
CTGCGCGCATTGCCGGTCGGCCAGGGCGCGCAGCGGGTCGAGCTGGGCGCCATCGCCAAGCTGTCGCGCGACTACGCCGA
GCGGCCGCGGCAGATCATCCGCCACAACGGCCAGGCGGCACTAACCCTGGGCGTCAGCGGGGTCTCGGGAGCGAATATCG
TCGAGGTCGGACACAGCGTCGAAGCGGCGTTGCAGGCCATCGAACACCGCATGCCACTGGGCGCCGAACTGCATCCGCTG
TACGAGCAGCACCAGATCGTCGATGAGTCGGTGAACAGCTTCGCGCTCAACGTGTTCCTCTCGGTGGCCATCGTGGTCGG
CGTGCTGTGCATCGCCATGGGTCTGCGCGCCGGCGTCATCATTGGCGCGGTGCTGTTTCTCACCGTGCTCGGCACGCTGC
TGGTGATGTGGCTGGCGGGCATCGAGTTGGAGCGAATTTCCCTCGGCGCACTGATCATCGCCATGGGCATGCTGGTCGAC
AATGCGGTCGTGGTCTGCGACGGCATGCTGGTGCGCCAGCGCCAGGGCAAGAGCATCCTCGAAGCCTCACAGGAAACGCT
GCATCAGACGCAGTGGCCGCTGCTCGGCGCCACCATCATCGGCATCCTCGCCTTCGCCGGCATTGGTCTATCCCAGGACA
CCACCGGCGAGTTCCTCTTCTCGCTGTTCTTCGTCATCGCCGTGTCGCTGCTGCTCAGCTGGCTGCTGGCGTTGCTGCTG
GTGCCGCTGTTCGGTCATTACCTGCTGCGCAACGCCAAGACCGACGAGGACCCCGACGCCGCCTACGACGGCCCCTGGTA
CAACCGCTACCGCCGACTGGCCGGCGGAGTGCTGCATCGGCCCTGGCTGACGGTCGGCGTGCTAGTAGTGCTGACGGTGG
TCAGTATGGTGCTGTTCACCCGCTTGCCGCAGAGCTTCTTCCCGCCGTCGAGCACGCCGCTTTTCTACGTCAATCTGTTC
CTGCCACAGGGCACGCATATTCGCGAGACCGCAGAGACCGCCTCTGACGTGGAGGCGTATTTGGCGGAGCTGGAGGGGGT
AAGCGAGGTGTCCAGCTTCATCGGCGCCGGAGCCTCGCGCTTCATGCTGACCTATATGCCGGAGCAGCCGAATTCGTCGC
TGATGCACTTTCTCGTGCGCACCGAGGATGCCGAGCTGATCGCCGGGCTGGTGAGGCAGATCAACCAGCAGCTGCCACAA
CGCTATCCCTCGGCCGACGTCTCGGCTGCGCAGTTCATGTTCGGCCCCAATGCCGAGGCCAAGCTGGAAGCGCGCATCAG
CGGCCCGGACATCGAGGTGCTGCGGGCCATTTCCGCCGAAGGCCGCAAGCGCCTGCAGGATGAGGGCAAGGTTTTCAACG
TGCGCGACGACTGGCGCCAGCAGGTACTGGTGCTCCGCCCGCAACTGGCGCTGGATCGCCTCGCCGATGCCGGCCTGACG
CGCCAGGCCGTGGCACGTGCCCTGGCCGCCGGCAGCGAAGGCCAACGGGTCAGCCTGCTGCGCGAGCGCGACGAGCTGAT
CCCGGTATTGCTGCGCGCCGCGCCGGAGGACCGCATCGATAGCGGTGACCTGCTGCAACGCCTGATCTGGAGCCCCGCCG
GCACCGGCTACGTGCCACTGGCGCAGGTCGCCGACAGCATCGAGCCGGTCAGCGAGGACAGCATCATCGTGCGCTACGAC
CGCGAGCGGACGATCTCCATCCGCGCCGACCCGCGCGACGGCGAGAACACCAACGCGGCACACGAGCGCATTCGCCCGCT
GATCGAGGGCATCGAGCTGCCGGTCAACTACAGCCTGAAATGGGGCGGCGACTACGAACAGTCTTCCGAGGCCCAGCAGG
CGCTGGCCAGCACGCTGGCGGTGCCCTACCTGGCAATGGTGCTGGTCACCGTGCTGCTGTTCGCCAGGGTGCGCCAGCCG
CTGATGATCTGGCTGGTGGTGCCCATGGCGATCTGCGGGGTGAGCTTCGGCCTGCTGCTCACCGGTCAGGCGTTCGGCTT
CATGGCACTGCTCGGCCTGCTCAGCCTGACCGGCATGCTGATCAAGAACGCCGTGGTGCTGGTGGACGAGATCGACCGGC
AGATCGACGACGAGGTGCCGCGCCTGACCGCCATCATCGAAGCCTCGGCGTCGCGCCTGCGACCGGTGATGATGGCCGCC
GGCACCACCGTACTGGGCATGGTGCCGCTGCTGTTCGACCCGTTCTTCGCCAACATGGCGGTTACCATCATGGGCGGCCT
GGGCTTCGCCACGTTGCTGACGCTGCTGGCGGTGCCGTGCCTGTACCTGCTGTTCATGAAAGTGCGCCCGGAGGAAACCG
CATGA

Protein sequence :
MDFARYAITRPVNIWILILICLLGGTLAFFEIGRLEDPEFTIKQAIVNVQYPGATALEVEQQVTEPLESAIQQMSQIKEL
RSRSMPGIAEIRVEMQDRYDGDALPQIWDELRNKINDAQGDLPPGIEPPQVNDDFGDVYGIFYALTGDGLTLKELHETTK
DLRRALVAADGVGKVEIAGVQEERILVEVDQAQLAAMGIAPDEIAAALADTDAAVDAGGVHAGEYFVRLRPSGAFDSLEE
LRALPVGQGAQRVELGAIAKLSRDYAERPRQIIRHNGQAALTLGVSGVSGANIVEVGHSVEAALQAIEHRMPLGAELHPL
YEQHQIVDESVNSFALNVFLSVAIVVGVLCIAMGLRAGVIIGAVLFLTVLGTLLVMWLAGIELERISLGALIIAMGMLVD
NAVVVCDGMLVRQRQGKSILEASQETLHQTQWPLLGATIIGILAFAGIGLSQDTTGEFLFSLFFVIAVSLLLSWLLALLL
VPLFGHYLLRNAKTDEDPDAAYDGPWYNRYRRLAGGVLHRPWLTVGVLVVLTVVSMVLFTRLPQSFFPPSSTPLFYVNLF
LPQGTHIRETAETASDVEAYLAELEGVSEVSSFIGAGASRFMLTYMPEQPNSSLMHFLVRTEDAELIAGLVRQINQQLPQ
RYPSADVSAAQFMFGPNAEAKLEARISGPDIEVLRAISAEGRKRLQDEGKVFNVRDDWRQQVLVLRPQLALDRLADAGLT
RQAVARALAAGSEGQRVSLLRERDELIPVLLRAAPEDRIDSGDLLQRLIWSPAGTGYVPLAQVADSIEPVSEDSIIVRYD
RERTISIRADPRDGENTNAAHERIRPLIEGIELPVNYSLKWGGDYEQSSEAQQALASTLAVPYLAMVLVTVLLFARVRQP
LMIWLVVPMAICGVSFGLLLTGQAFGFMALLGLLSLTGMLIKNAVVLVDEIDRQIDDEVPRLTAIIEASASRLRPVMMAA
GTTVLGMVPLLFDPFFANMAVTIMGGLGFATLLTLLAVPCLYLLFMKVRPEETA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 7e-148 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
A458_03335 YP_006456344.1 RND efflux transporter BAC0519 Protein 3e-162 44
A458_03335 YP_006456344.1 RND efflux transporter BAC0428 Protein 3e-159 44
A458_03335 YP_006456344.1 RND efflux transporter BAC0425 Protein 3e-148 41
A458_03335 YP_006456344.1 RND efflux transporter BAC0526 Protein 2e-157 41